1. Signaling Pathways
  2. PROTAC
  3. Target Protein Ligand-Linker Conjugate

Target Protein Ligand-Linker Conjugate

Target Protein Ligand-Linker Conjugate incorporates a ligand for the target protein, a linker, which bring together E3 ubiquitin ligase and ubiquitinating machinery.

Target Protein Ligand-Linker Conjugate Related Products (2):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-44148
    FAK ligand-Linker Conjugate 1 2307461-45-4 98.28%
    FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation.
    FAK ligand-Linker Conjugate 1
  • HY-130499
    ERRα Ligand-Linker Conjugates 1
    ERRα Ligand-Linker Conjugates 1 incorporates a ligand for estrogen-related receptor alpha (ERRα), and a PROTAC linker, which recruit E3 ligases MDM2. ERRα Ligand-Linker Conjugates 1 can be used in the synthesis of a series of PROTACs, such as PROTAC ERRalpha Degrader-1 (HY-128838). PROTAC ERRalpha Degrader-1 is an ERRα degrader.
    ERRα Ligand-Linker Conjugates 1
Isoform Specific Products

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