2. Signaling Pathways
  3. Immunology/Inflammation
  4. BCL6

BCL6

B-cell lymphoma 6 protein; B-cell lymphoma 5 protein (BCL-5); Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51

 

BCL6 Related Products (2):

Cat. No. Product Name Effect Purity
  • HY-156531
    TCIP 1
    		Inhibitor
    TCIP 1 is a transcriptional/epigenetic CIPs (TCIP) small molecule consisting of covalent links to small molecules capable of binding to BCL6 and capable of binding to BRD4, respectively. TCIPs aids cell death gene expression by recruiting endogenous cancer drivers or downstream transcription factors to the promoters of cell death genes. TCIP 1 also plays a gain-of-function mechanism with shows cell specificity and tissue specificity. TCIP 1 forms a gain-of-function ternary complex with BCL6 and BRD4, Inhibits the blocking effect of BCL6 on apoptosis gene, and generates transcriptional extension of pro-apoptotic genes, thus activates apoptosis. TCIP 1 also significantly inhibits the expression of the oncogene MYC and inhibits the growth of diffuse large B-cell lymphoma (DLBCL).
  • HY-153521
    CCT374705
    		Inhibitor 99.30%
    CCT374705 is an orally active BCL6 inhibitor with potent antiproliferative effects in vitro. CCT374705 effectively inhibits tumor growth in a lymphoma xenograft mouse model.