1. Signaling Pathways
  2. Anti-infection
  3. HSV

HSV

HSV (Herpes simplex virus) can be spread when an infected person is producing and shedding the virus. Herpes simplex can be spread through contact with saliva, such as sharing drinks. Symptoms of herpes simplex virus infection include watery blisters in the skin or mucous membranes of the mouth, lips or genitals. Lesions heal with ascab characteristic of herpetic disease. As neurotropic and neuroinvasive viruses, HSV-1 and -2 persist in the body by becoming latent and hiding from the immune system in the cell bodies of neurons. After the initial or primary infection, some infected people experience sporadic episodes of viral reactivation or outbreaks.

HSV Related Products (39):

Cat. No. Product Name Effect Purity
  • HY-13966
    2-Deoxy-D-glucose Inhibitor >99.0%
    2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.
  • HY-16592
    Brefeldin A Inhibitor 99.79%
    Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. Brefeldin A is also an autophagy inhibitor. Brefeldin A has anti-cancer activity. Autophagy Inhibitor.
  • HY-B0180
    Imiquimod Inhibitor 99.96%
    Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist.
  • HY-13637
    Ganciclovir Inhibitor 99.77%
    Ganciclovir is a potent herpes simplex virus (HSV)inhibitor, including cytomegalovirus (CMV), with an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1).
  • HY-17422
    Acyclovir Inhibitor >98.0%
    Acyclovir, a molecule tailored to inactivate the thymidine kinase of the herpesvirus, is a guanosine analogue antiviral drug.
  • HY-19333
    OG-L002 Inhibitor 99.71%
    OG-L002 is a potent and highly selective LSD1 inhibitor with an IC50 of 0.02 μM. OG-L002 is a potent monoamine oxidases (MAO) inhibitor with IC50s of 1.38 μM and 0.72 μM for MAO-A and MAO-B, respectively. OG-L002 potently inhibits the expression of HSV IE genes.
  • HY-129555
    Surfactin Inhibitor
    Surfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. Surfactin can act as an antimicrobial adjuvant with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects. Surfactin also has antiviral activity against a variety of enveloped viruses.
  • HY-135117
    Glyceryl monocaprate Inhibitor >98.0%
    Glyceryl monocaprate (Monolaurin) is a 1-monoglyceride of capric acid against gram-positive bacterial infections. Glyceryl monocaprate (Monolaurin) has inhibitory effect on Herpes Simplex Virus (HSV) and offers an effective treatment for herpes labialiss.
  • HY-B0277
    Vidarabine Inhibitor >98.0%
    Vidarabine (Ara-A) an antiviral drug which is active against herpes simplex and varicella zoster viruses.
  • HY-N0039
    Ginsenoside Rb1 Inhibitor >98.0%
    Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with an IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65 .
  • HY-A0061
    Trifluridine Inhibitor 99.72%
    Trifluridine (Trifluorothymidine; 5-Trifluorothymidine; TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral drug for herpes simplex virus (HSV) infection.
  • HY-12653
    LDC4297 Inhibitor 99.14%
    LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.
  • HY-B0307
    Idoxuridine Inhibitor 99.88%
    Idoxuridine is an antiviral agent for feline herpesvirus type-1 with IC50 of 4.3 μM.
  • HY-15303
    Pritelivir Inhibitor 98.47%
    Pritelivir (BAY 57-1293; AIC316) represents a new class of potent inhibitors of herpes simplex virus (HSV) that target the virus helicase primase complex.
  • HY-12725
    ML324 Inhibitor >98.0%
    ML324 is a potent JMJD2 demethylase inhibitor with demonstrated antiviral activity.
  • HY-N0021
    Verbascoside Inhibitor 99.61%
    Verbascoside is isolated from Lantana camara, acts as an ATP-competitive inhibitor of PKC, with an IC50 of 25 µM, and has antitumor, anti-inflammatory and antineuropathic pain activity.
  • HY-17424
    Penciclovir Inhibitor >98.0%
    Penciclovir is reported to be potent against HSV types 1 and 2 with IC50 of 0.04-1.8 μg/mL and 0.06-4.4 μg/mL, respectively.
  • HY-17425A
    Valacyclovir hydrochloride Inhibitor 99.85%
    Valacyclovir hydrochloride is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B.
  • HY-N1430
    Oxyresveratrol Inhibitor 99.91%
    Oxyresveratrol is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia.
  • HY-14809
    Amenamevir Inhibitor 99.81%
    Amenamevir is a helicase-primase inhibitor which has potent antiviral activity against HSVs with an EC50 of 14 ng/mL.
Isoform Specific Products

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