1. Signaling Pathways
  2. Anti-infection
  3. HSV

HSV

HSV (Herpes simplex virus) can be spread when an infected person is producing and shedding the virus. Herpes simplex can be spread through contact with saliva, such as sharing drinks. Symptoms of herpes simplex virus infection include watery blisters in the skin or mucous membranes of the mouth, lips or genitals. Lesions heal with ascab characteristic of herpetic disease. As neurotropic and neuroinvasive viruses, HSV-1 and -2 persist in the body by becoming latent and hiding from the immune system in the cell bodies of neurons. After the initial or primary infection, some infected people experience sporadic episodes of viral reactivation or outbreaks.

HSV Related Products (36):

Cat. No. Product Name Effect Purity
  • HY-13966
    2-Deoxy-D-glucose Inhibitor >99.0%
    2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.
  • HY-16592
    Brefeldin A Inhibitor 99.79%
    Brefeldin A (BFA) is a specific inhibitor of protein trafficking which blocks the protein transport from the endoplasmic reticulum to the Golgi complex.
  • HY-B0180
    Imiquimod Inhibitor 99.96%
    Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist.
  • HY-13637
    Ganciclovir Inhibitor 99.77%
    Ganciclovir is a potent herpes simplex virus (HSV)inhibitor, including cytomegalovirus (CMV), with an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1).
  • HY-17422
    Acyclovir Inhibitor >98.0%
    Acyclovir, a molecule tailored to inactivate the thymidine kinase of the herpesvirus, is a guanosine analogue antiviral drug.
  • HY-N6733
    Aphidicolin Inhibitor >99.0%
    Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering with the activity of DNA polymerase. Aphidicolin is an antibiotic produced by the mold Cephalosporium aphidicola. Aphidicolin is a potent inhibitor of cellular deoxyribonucleic acid synthesis and inhibits the growth of herpes simplex virus. Aphidicolin potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.
  • HY-N7041
    11-Oxomogroside IIa Inhibitor
    11-Oxomogroside IIa (11-oxomogroside II A1) is a cucurbitane glycoside extracted from the fruits of Siraitia grosVenorii. 11-Oxomogroside IIa has inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), shows weak inhibitory effects on activation of (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor.
  • HY-129555
    Surfactin Inhibitor
    Surfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. Surfactin can act as an antimicrobial adjuvant with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects. Surfactin also has antiviral activity against a variety of enveloped viruses.
  • HY-B0277
    Vidarabine Inhibitor >98.0%
    Vidarabine (Ara-A) an antiviral drug which is active against herpes simplex and varicella zoster viruses.
  • HY-12653
    LDC4297 Inhibitor 99.14%
    LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.
  • HY-A0061
    Trifluridine Inhibitor 99.69%
    Trifluridine (Trifluorothymidine; 5-Trifluorothymidine; TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral drug for herpes simplex virus (HSV) infection.
  • HY-N0039
    Ginsenoside Rb1 Inhibitor >98.0%
    Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with an IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65 .
  • HY-12725
    ML324 Inhibitor >98.0%
    ML324 is a potent JMJD2 demethylase inhibitor with demonstrated antiviral activity.
  • HY-B0307
    Idoxuridine Inhibitor 99.88%
    Idoxuridine is an antiviral agent for feline herpesvirus type-1 with IC50 of 4.3 μM.
  • HY-15303
    Pritelivir Inhibitor 98.47%
    Pritelivir (BAY 57-1293; AIC316) represents a new class of potent inhibitors of herpes simplex virus (HSV) that target the virus helicase primase complex.
  • HY-N0021
    Verbascoside Inhibitor 99.61%
    Verbascoside is isolated from Lantana camara, acts as an ATP-competitive inhibitor of PKC, with an IC50 of 25 µM, and has antitumor, anti-inflammatory and antineuropathic pain activity.
  • HY-N1430
    Oxyresveratrol Inhibitor 99.91%
    Oxyresveratrol is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia.
  • HY-17425A
    Valacyclovir hydrochloride Inhibitor 99.85%
    Valacyclovir hydrochloride is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B.
  • HY-17424
    Penciclovir Inhibitor >98.0%
    Penciclovir is reported to be potent against HSV types 1 and 2 with IC50 of 0.04-1.8 μg/mL and 0.06-4.4 μg/mL, respectively.
  • HY-B1268
    Docusate Sodium Inhibitor >98.0%
    Docusate Sodium is a laxative used to treat constipation, for constipation due to the use of opiates it maybe used with a stimulant laxative, can be taken by mouth or rectally.
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