1. Signaling Pathways
  2. Immunology/Inflammation
  3. COX
  4. COX-1 Isoform

COX-1

 

COX-1 Related Products (111):

Cat. No. Product Name Effect Purity
  • HY-66005
    Acetaminophen
    Inhibitor 99.98%
    Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent.
  • HY-14397
    Indomethacin
    Inhibitor 99.97%
    Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively.
  • HY-14398
    Celecoxib
    Inhibitor 99.59%
    Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC50 of 40 nM.
  • HY-14654
    Aspirin
    Inhibitor 99.66%
    Aspirin (Acetylsalicylic Acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively.
  • HY-15036
    Diclofenac
    Inhibitor 99.97%
    Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively.
  • HY-78131C
    Ibuprofen sodium
    Inhibitor 99.89%
    Ibuprofen ((±)-Ibuprofen) sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM.
  • HY-B0227A
    Ketoprofen (lysinate)
    Inhibitor
    Ketoprofen (RP-19583) lysinate is a non-steroidal anti-inflammatory agent.
  • HY-14654A
    Aspirin lithium
    Inhibitor
    Aspirin (Acetylsalicylic Acid) lithium is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively.
  • HY-78131
    Ibuprofen
    Inhibitor 99.93%
    Ibuprofen ((±)-Ibuprofen) is a potent, orally active, selective COX-1 inhibitor with an IC50 value of 13 μM.
  • HY-B1227
    Carprofen
    Inhibitor 99.96%
    Carprofen is a nonsteroid anti-inflammatory agent, acts as a multi-target FAAH/COX inhibitor, with IC50s of 3.9 μM, 22.3 μM and 78.6 μM for COX-2, COX-1 and FAAH, respectively.
  • HY-N0898
    Catechin
    Inhibitor 99.57%
    Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
  • HY-N0001
    (-)-Epicatechin
    Inhibitor 99.0%
    (-)-Epicatechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM.
  • HY-N1067
    Xanthohumol
    Inhibitor 99.84%
    Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities.
  • HY-15037
    Diclofenac Sodium
    Inhibitor 99.92%
    Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively.
  • HY-59105
    SC-560
    Inhibitor 99.80%
    SC-560 is a potent and selective COX-1 inhibitor with an IC50 of 9 nM.
  • HY-B0261
    Meloxicam
    Inhibitor 99.88%
    Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively.
  • HY-15030
    Naproxen
    Inhibitor 99.99%
    Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay.
  • HY-B0227
    Ketoprofen
    Inhibitor 99.93%
    Ketoprofen (RP-19583) is a non-steroidal anti-inflammatory agent.
  • HY-N0002
    (-)-Epicatechin gallate
    Inhibitor 98.57%
    (-)-Epicatechin gallate (Epicatechin gallate) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 7.5 μM.
  • HY-N0147
    Rutaecarpine
    Inhibitor 99.00%
    Rutaecarpine, an alkaloid of Evodia rutaecarpa, is an inhibitor of COX-2 with an IC50 value of 0.28 μM.