1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. CSF & Receptors
  4. multi-CSF/IL-3

Multi-colony-stimulating factor (multi-CSF; IL-3) is one of the hematopoietic bone marrow cell's growth factor produced primarily by the bone marrow cells and by antigen or mitogen-activated T cells. It is capable to stimulate the proliferation of early haemopoietic progenitor cells in the bone marrow. Multi-CSF signal through heterodimeric cell-surface receptors (IL-3Rs) that consist of two subunits, the α subunit specific to each and the β common chain (βc). The β subunit is common to GM-CSF, IL-3 and IL-5 receptors. Activation of the IL-3R is thought to involve sequential assembly of a receptor signaling complex whereby the critical step is the initial binding of IL-3 to IL3Rα, followed by recruitment of βc and the assembly of a high order complex which, by analogy with the GM-CSF receptor, would bring JAK2 molecules together to trigger downstream signaling. Multi-CSF is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. It has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.

Cat. No. Product Name / Synonyms Species Source
  • HY-P70576
    IL-3 Protein, Human (His)

    Interleukin-3; IL-3; Hematopoietic Growth Factor; Mast Cell Growth Factor; MCGF; Multipotential Colony-Stimulating Factor; P-Cell-Stimulating Factor; IL3

    Human E. coli
  • HY-P70685
    IL-3 Protein, Mouse (HEK293, His)

    Interleukin-3; IL-3; Hematopoietic growth factor; Multipotential colony-stimulating factor; P-cell-stimulating factor; Il3; Il-3; Mast cell growth factor; MCGF

    Mouse HEK293
    IL-3 Protein, Mouse (HEK293, His) is a multilineage hematopoietic cytokine with promising effects on platelet and neutrophil counts and special usefulness in patients with secondary hematopoietic failure.
  • HY-P70765
    IL-3 Protein, Human (133a.a, HEK293, His)

    Interleukin-3; IL-3; Hematopoietic Growth Factor; Mast Cell Growth Factor; MCGF; Multipotential Colony-Stimulating Factor; P-Cell-Stimulating Factor; IL3

    Human HEK293
    IL-3 Protein, Human (133a.a, HEK293, His) is a multipotent hematopoietic growth factor that can control blood formation. IL-3 Protein, Human (HEK293, His) is a recombinant human interleukin-3 (rhIL-3) expressed in HEK 293 cells with a His tag. rhIL-3 is also a weak inflammatory mediator. rhIL-3 can be used to improve states of hematopoietic failure.
  • HY-P7040A
    IL-3 Protein, Human (CHO)

    rHuIL-3; Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor

    Human CHO
    IL-3 Protein, Human (CHO) is a multilineage hematopoietic cytokine with promising effects on platelet and neutrophil counts and special usefulness in patients with secondary hematopoietic failure.
  • HY-P73207
    IL-3 Protein, Mouse (HEK293)

    Interleukin-3; IL-3; MCGF

    Mouse HEK293
  • HY-P70576G
    GMP IL-3 Protein, Human (His)

    Interleukin-3; IL-3; Hematopoietic Growth Factor; Mast Cell Growth Factor; MCGF; Multipotential Colony-Stimulating Factor; P-Cell-Stimulating Factor; IL3

    Human E. coli
  • HY-P73205
    IL-3 Protein, Human (152a.a, HEK293, His)

    Interleukin-3; IL-3; MCGF

    Human HEK293
  • HY-P73206
    IL-3 Protein, Human (sf9, His)

    Interleukin-3; IL-3; MCGF

    Human Sf9 insect cells
  • HY-P73208
    IL-3 Protein, Rat (sf9, His)

    Interleukin-3; IL-3; MCGF

    Rat Sf9 insect cells
  • HY-P78465
    IL-3 Protein, Human (His-Avi)

    IL3; IL-3; IL-3MGC79398; interleukin-3; MULTI-CSF; MCGF

    Human E. coli
  • HY-P7062
    IL-3 Protein, Mouse

    rMuIL-3; Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor

    Mouse E. coli
    IL-3 Protein, Mouse is a pleiotropic cytokine containing 135 amino acids, which functions via specific cell surface receptors to stimulate the proliferation, differentiation and survival of haematopoietic cell lines.
  • HY-P7040
    IL-3 Protein, Human

    rHuIL-3; Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor

    Human E. coli
    IL-3 Protein, Human is a multilineage hematopoietic cytokine with promising effects on platelet and neutrophil counts and special usefulness in patients with secondary hematopoietic failure.
  • HY-P7375
    IL-3 Protein, Rat (CHO, His)

    rRtIL-3, His; MCGF; Hematopoietic growth factor; P-cell stimulation factor

    Rat CHO
    IL-3 Protein, Rat (CHO, His) is a growth factor for a variety of hematopoietic progenitor cells.
  • HY-P78313
    IL-3 Protein, Mouse (HEK293, Fc)

    IL3; IL-3; IL-3MGC79398; interleukin-3; MULTI-CSF; MCGF

    Mouse HEK293
  • HY-P7216
    IL-3 Protein, Canine

    rCaIL-3; Mast cell growth factor; MCGF; Hematopoietic growth factor

    Canine E. coli
    IL-3 Protein, Canine is a hemopoietic growth factor involved in the survival, proliferation and differentiation of multipotent hemopoietic cells.
  • HY-P700205AF
    Animal-Free IL-3 Protein, Mouse (His)

    rMuIL-3; Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor

    Mouse E. coli
  • HY-P70576AF
    Animal-Free IL-3 Protein, Human (His)

    rHuIL-3; Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor

    Human E. coli
Cat. No. Product Name Effect Purity