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CX3C chemokine family (δ-chemokines) has the two N-terminal cysteine residues separated by three variable amino acids in the conserved position. This family contains only one ligand, called CX3CL1, also known as fractalkine or neurotactin, which is unique in possessing a mucin-like glycosylated stalk that allows it to exist as a soluble or membrane-bound chemokine. CX3CR1 is a 7-transmembrane receptor for CX3CL1 and mediates both its adhesive and migratory functions. In addition, it is shown that CX3CL1 and CX3CR1 are involved in the pathogenesis of various clinical disease states, such as atherosclerosis, glomerulonephritis, cardiac allograft rejection, and rheumatoid arthritis.
The Fractalkine/CX3CL1 protein is a multifunctional chemokine that binds to CX3CR1 and the integrins ITGAV:ITGB3 and ITGA4:ITGB1. It regulates immune responses, inflammation, cell adhesion, and chemotaxis. Fractalkine/CX3CL1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Fractalkine/CX3CL1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Fractalkine/CX3CL1 Protein, Mouse (HEK293, His) is 313 a.a., with molecular weight of ~55-85 kDa.
Fractalkine/CX3CL1 protein, a chemokine, binds CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. It regulates immune response, inflammation, adhesion, chemotaxis, and leukocyte migration. It activates integrins via CX3CR1-dependent and -independent pathways, binding to site 1 with CX3CR1 and site 2 without CX3CR1. Soluble Fractalkine/CX3CL1 attracts T-cells and monocytes, not neutrophils. Fractalkine/CX3CL1 Protein, Human (315a.a, HEK293, His) is the recombinant human-derived Fractalkine/CX3CL1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Fractalkine/CX3CL1 Protein, Human (315a.a, HEK293, His) is 315 a.a., with molecular weight of 50-90 kDa.
The Fractalkine/CX3CL1 protein is a multifunctional chemokine that binds to CX3CR1 and the integrins ITGAV:ITGB3 and ITGA4:ITGB1. It regulates immune responses, inflammation, cell adhesion, and chemotaxis. Fractalkine/CX3CL1 Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived Fractalkine/CX3CL1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Fractalkine/CX3CL1 Protein, Mouse (Biotinylated, HEK293, His-Avi) is 312 a.a., with molecular weight of 70-83 kDa.
Fractalkine/CX3CL1 is a chemokine that acts as a ligand to CX3CR1 and the integrins ITGAV: ITGB3 and ITGA4: ITGB1. CX3CL1 promotes lung cancer cell migration and invasion through the Src/FAK signaling pathway. CX3CL1 plays an important role in immune response, inflammation, cell adhesion and chemotaxis. Fractalkine/CX3CL1 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived Fractalkine/CX3CL1 protein, expressed by HEK293 , with C-Avi, C-10*His labeled tag. The total length of Fractalkine/CX3CL1 Protein, Human (Biotinylated, HEK293, His) is 317 a.a., with molecular weight of 50-90 kDa.
Fractalkine/CX3CL1 protein is a versatile chemokine that acts as a ligand for CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. It regulates immune response, inflammation, adhesion, and chemotaxis. It activates integrins via CX3CR1-dependent and -independent pathways, binding to site 1 with CX3CR1 and site 2 without CX3CR1. Soluble Fractalkine/CX3CL1 attracts T-cells and monocytes, not neutrophils. Fractalkine/CX3CL1 Protein, Rat is the recombinant rat-derived Fractalkine/CX3CL1 protein, expressed by E. coli , with tag free. The total length of Fractalkine/CX3CL1 Protein, Rat is 79 a.a., with molecular weight of ~11 kDa.
Fractalkine/CX3CL1 protein, a chemokine, binds CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. It regulates immune response, inflammation, adhesion, chemotaxis, and leukocyte migration. It activates integrins via CX3CR1-dependent and -independent pathways, binding to site 1 with CX3CR1 and site 2 without CX3CR1. Soluble Fractalkine/CX3CL1 attracts T-cells and monocytes, not neutrophils. Fractalkine/CX3CL1 Protein, Human (339a.a, HEK293, His) is the recombinant human-derived Fractalkine/CX3CL1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Fractalkine/CX3CL1 Protein, Human (339a.a, HEK293, His) is 315 a.a., with molecular weight of ~35 kDa.
Fractalkine/CX3CL1 protein, a chemokine, binds CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. It regulates immune response, inflammation, adhesion, chemotaxis, and leukocyte migration. It activates integrins via CX3CR1-dependent and -independent pathways, binding to site 1 with CX3CR1 and site 2 without CX3CR1. Soluble Fractalkine/CX3CL1 attracts T-cells and monocytes, not neutrophils. Fractalkine/CX3CL1 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived Fractalkine/CX3CL1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Fractalkine/CX3CL1 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is 100 a.a., with molecular weight of ~40.8 & 35.2 kDa, respectively.
Fractalkine/CX3CL1 protein, a chemokine, binds CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. It regulates immune response, inflammation, adhesion, chemotaxis, and leukocyte migration. It activates integrins via CX3CR1-dependent and -independent pathways, binding to site 1 with CX3CR1 and site 2 without CX3CR1. Soluble Fractalkine/CX3CL1 attracts T-cells and monocytes, not neutrophils. Fractalkine/CX3CL1 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived Fractalkine/CX3CL1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Fractalkine/CX3CL1 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is 100 a.a., with molecular weight of ~10.1 KDa.
Fractalkine/CX3CL1 Protein, a member of the intercrine beta family, plays a pivotal role in chemokines crucial for intercellular communication and immune responses. Within this family, Fractalkine/CX3CL1 likely modulates inflammatory processes and cellular interactions significantly. Further exploration is essential to unveil its specific functions and implications within the broader chemokine CC family, emphasizing its importance in mediating immune responses and contributing to the intricate network of intercellular signaling. Fractalkine/CX3CL1 Protein, Canine (HEK293) is the recombinant canine-derived Fractalkine/CX3CL1 protein, expressed by HEK293, with tag free. The total length of Fractalkine/CX3CL1 Protein, Canine (HEK293) is 355 a.a., with molecular weight of 64-69 kDa.
Fractalkine/CX3CL1 Protein, a member of the intercrine beta family, plays a pivotal role in chemokines crucial for intercellular communication and immune responses. Within this family, Fractalkine/CX3CL1 likely modulates inflammatory processes and cellular interactions significantly. Further exploration is essential to unveil its specific functions and implications within the broader chemokine CC family, emphasizing its importance in mediating immune responses and contributing to the intricate network of intercellular signaling. Fractalkine/CX3CL1 Protein, Canine (HEK293, Fc) is the recombinant canine-derived Fractalkine/CX3CL1 protein, expressed by HEK293, with C-hFc labeled tag. The total length of Fractalkine/CX3CL1 Protein, Canine (HEK293, Fc) is 379 a.a., with molecular weight of 70-100 kDa.
Fractalkine/CX3CL1 Protein, a member of the intercrine beta family, plays a pivotal role in chemokines crucial for intercellular communication and immune responses. Within this family, Fractalkine/CX3CL1 likely modulates inflammatory processes and cellular interactions significantly. Further exploration is essential to unveil its specific functions and implications within the broader chemokine CC family, emphasizing its importance in mediating immune responses and contributing to the intricate network of intercellular signaling. Fractalkine/CX3CL1 Protein, Canine (HEK293, His) is the recombinant canine-derived Fractalkine/CX3CL1 protein, expressed by HEK293, with C-His labeled tag. The total length of Fractalkine/CX3CL1 Protein, Canine (HEK293, His) is 100 a.a., with molecular weight of ~38.9 kDa.
The Fractalkine/CX3CL1 protein is a member of the intercrine beta family and plays a key role in chemokines that are critical for intercellular communication and immune responses. In this family, Fractalkine/CX3CL1 may significantly regulate inflammatory processes and cellular interactions. Fractalkine/CX3CL1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Fractalkine/CX3CL1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Fractalkine/CX3CL1 Protein, Cynomolgus (HEK293, His) is 317 a.a., with molecular weight of 50-70 kDa.
