1. Recombinant Proteins
  2. Enzymes & Regulators
  3. Transferases (EC 2)

Enzymes can be classified systematically according to the difference between reaction and substrate specificity, and the mechanism of action. Transferases (EC 2.x.x.x) are a large class of enzymes that catalyse the transfer of a functional group, such as amine, carboxyl, carbonyl, methyl, acyl, glycosyl, and phosphoryl from a donor molecule to an acceptor molecule. Transferases are involved in hundreds of different biochemical pathways throughout biology, and are integral to some of life’s most important processes. Transferases includes: EC 2.1 (e.g. methyltransferase), EC 2.2 (e.g. transketolase), EC 2.3 (e.g. acyltransferase), EC 2.4 (e.g. glycosyltransferase), EC 2.5 (e.g. riboflavin synthase), EC 2.6 (e.g. transaminase), EC 2.7 (e.g. kinases), EC 2.8 (e.g. sulfurtransferase), EC 2.9 (e.g. selenotransferase), and EC 2.10 (e.g. molybdenumtransferase).

Cat. No. Product Name / Synonyms Species Source
  • HY-P74652
    PARP Protein, Human (sf9, His)

    ADPRT 1; ADPRT; PARP apoptosis; PARP; PPOL

    Human Sf9 insect cells
    The PARP1 protein is a polyADP-ribosyltransferase that crucially mediates polyADP-ribosylation (PARsylation) in DNA repair, including base excision and double-strand breaks. By interacting with factors such as HPF1 and NMNAT1, the specificity of PARP1 extends to various amino acids. PARP Protein, Human (sf9, His) is the recombinant human-derived PARP protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of PARP Protein, Human (sf9, His) is 1014 a.a., with molecular weight of 100-110 kDa.
  • HY-P73255
    IRAK4 Protein, Human (sf9, His)

    Interleukin-1 receptor-associated kinase 4; IPD1; IRAK4; NY-REN-64; REN64

    Human Sf9 insect cells
    IRAK4 Protein, a serine/threonine-protein kinase, is pivotal in initiating innate immune responses via Toll-like receptor (TLR) and IL-1R signaling pathways. Upon TLR activation, it rapidly forms the Myddosome with IRAK2. IRAK4 phosphorylates IRAK1, promoting its autophosphorylation, and phosphorylates Pellino proteins to facilitate IRAK1 polyubiquitination. This leads to NF-kappa-B activation and regulates immune responses during microbial infections. Additionally, it phosphorylates TIRAP, influencing its ubiquitination and degradation. IRAK4 Protein, Human (sf9, His) is the recombinant human-derived IRAK4 protein, expressed by Sf9 insect cells , with N-10*His labeled tag. The total length of IRAK4 Protein, Human (sf9, His) is 460 a.a., with molecular weight of ~48 kDa.
  • HY-P73678
    RET Protein, Human (sf9, His-GST)

    Proto-oncogene tyrosine-protein kinase receptor Ret; RET; CDHF12; CDHR16

    Human Sf9 insect cells
    RET protein is a receptor tyrosine protein kinase that plays a key role in cell proliferation, neuronal navigation, and differentiation upon binding to glial cell-derived neurotrophic factor family ligands. It regulates the delicate balance between cell death and survival, influences positional information, and is critical for intestinal organogenesis, enteric nervous system development, renal organogenesis, and Peyer's patch formation. RET Protein, Human (sf9, His-GST) is the recombinant human-derived RET protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of RET Protein, Human (sf9, His-GST) is 457 a.a., with molecular weight of ~70 kDa.
  • HY-P75181
    FUT8 Protein, Human (sf9, His)

    Alpha-(1,6)-fucosyltransferase; Alpha1-6FucT; FUT8; Fucosyltransferase 8

    Human Sf9 insect cells
    FUT8 protein serves as a catalyst in the glycosylation process, specifically adding fucose in an alpha 1-6 linkage to the first GlcNAc residue located adjacent to peptide chains in N-glycans. This enzymatic activity plays a crucial role in modifying glycoproteins, contributing to the structural diversity and functional properties of N-glycans. By facilitating the addition of fucose in a specific linkage, FUT8 participates in the intricate molecular landscape of glycosylation, influencing various cellular processes and interactions involving glycoproteins. FUT8 Protein, Human (sf9, His) is the recombinant human-derived FUT8 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of FUT8 Protein, Human (sf9, His) is 508 a.a., with molecular weight of ~55 kDa.
  • HY-P7803
    PKM2 Protein, Human (420 a.a, His)

    rHuPyruvate Kinase M2/PKM2, His; Pyruvate Kinase M2; PKM2; CTHBP; OIP-3; THBP1

    Human E. coli
    PKM2 Protein, Human (420 a.a, His) is a multifunctional protein, is exclusively expressed in embryonic and adult dividing/tumor cells. PKM2 can catabolize glucose and involved in many nonglycolytic pathways.
  • HY-P76263
    CK2 alpha/CSNK2A1 Protein, Human (sf9, GST)

    Casein kinase II subunit alpha; CK II alpha; CSNK2A1; CK2A1

    Human Sf9 insect cells
    CK2α/CSNK2A1 protein can phosphorylate serine or threonine. It is involved in the regulation of cell cycle, apoptosis, transcription and viral infection, and has protective effects on the spindle assembly checkpoint and p53/TP53-mediated apoptosis. CK2α/CSNK2A1 can also participate in signal transduction by phosphorylating various factors, affecting circadian clock function and virus life cycle. CK2 alpha/CSNK2A1 Protein, Human (sf9, GST) is the recombinant human-derived CK2 alpha/CSNK2A1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of CK2 alpha/CSNK2A1 Protein, Human (sf9, GST) is 391 a.a., with molecular weight of ~65 KDa.
  • HY-P7308
    TrkA Protein, Human (HEK293)

    rHuTrkA; NTRK1; MTC; TRK

    Human HEK293
    TrkA Protein, Human (HEK293) is the high affinity catalytic receptor for the neurotrophin, nerve growth factor (NGF), and mediates the multiple effects of NGF, which include neuronal differentiation and avoidance of programmed cell death.
  • HY-P74114
    GSK-3 beta Protein, Human (sf9, His)

    Glycogen synthase kinase-3 beta; GSK-3 beta; Gsk3b

    Human Sf9 insect cells
    The TrkA protein is a receptor protein that binds to the neurotrophin nerve growth factor (NGF). It plays a crucial role in the development and survival of neurons. GSK-3 beta Protein, Human (sf9, His) is the recombinant human-derived GSK-3 beta protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of GSK-3 beta Protein, Human (sf9, His) is 433 a.a., with molecular weight of 44-48 kDa.
  • HY-P75927
    MGAT5 Protein, Human (HEK293, His)

    Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; GNT-V; Secreted GNT-V; MGAT5; GGNT5

    Human HEK293
    MGAT5 protein is a key enzyme that catalyzes the addition of N-acetylglucosamine (GlcNAc) in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. This catalytic activity is crucial for the biosynthesis of branched, complex-type N-glycans found on various proteins, including EGFR, TGFR (TGF-beta receptor), and CDH2. Through its involvement in complex N-glycan biosynthesis, MGAT5 plays a pivotal role in cellular signaling pathways, actin cytoskeleton reorganization, cell-cell adhesion, and cell migration. Notably, MGAT5-dependent EGFR N-glycosylation prolongs EGFR signaling by preventing rapid endocytosis. MGAT5 is also essential for efficient interactions between TGFB1 and its receptor, enhancing intracellular signaling pathways activated by growth factors like FGF2, PDGF, IGF, TGFB1, and EGF. Additionally, MGAT5-mediated CDH2 N-glycosylation inhibits homotypic cell-cell adhesion, influencing downstream signaling pathways and promoting cell migration. In the immune response, MGAT5-dependent TCR N-glycosylation limits TCR clustering and dampens TCR-mediated responses to antigens, contributing to normal leukocyte evasion and accumulation at inflammatory sites. Moreover, MGAT5 inhibits monocyte attachment to vascular endothelium and subsequent diapedesis, while also promoting proliferation of endothelial cells and angiogenesis by facilitating the release of FGF2 from the extracellular matrix. In summary, MGAT5 emerges as a multifaceted regulator with significant implications in cellular processes, immune responses, and angiogenesis. MGAT5 Protein, Human (HEK293, His) is the recombinant human-derived MGAT5 protein, expressed by HEK293 , with C-His labeled tag. The total length of MGAT5 Protein, Human (HEK293, His) is 553 a.a., with molecular weight of 75 kDa.
  • HY-P76094
    ST6GAL1 Protein, Mouse (HEK293, His)

    Beta-Galactoside Alpha-2; 6-Sialyltransferase 1; Sialyltransferase 1; ST6GAL1; SIAT1

    Mouse HEK293
    ST6GAL1 Protein catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. ST6GAL1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ST6GAL1 protein, expressed by HEK293 , with N-His labeled tag. The total length of ST6GAL1 Protein, Mouse (HEK293, His) is 377 a.a., with molecular weight of 50-55 kDa.
  • HY-P70014
    CDK2 Protein, Human (His)

    rHuCyclin-dependent kinase 2/CDK2, His; Cyclin-Dependent Kinase 2; Cell Division Protein Kinase 2; p33 Protein Kinase; CDK2; CDKN2

    Human E. coli
    CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2 Protein, Human (His) is the recombinant human-derived CDK2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of CDK2 Protein, Human (His) is 298 a.a., with molecular weight of 32-35 kDa.
  • HY-P71090
    PFKM Protein, Human (HEK293, His)

    6-phosphofructokinase; muscle type; Phosphofructo-1-kinase isozyme A; Phosphofructokinase 1; Phosphohexokinase; PFKM; PFKX

    Human HEK293
    PFKM protein, a key regulator in cellular metabolism, catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, initiating glycolysis. This fundamental enzymatic step controls glucose entry into glycolysis, influencing downstream energy production and cellular metabolism. PFKM's pivotal role highlights its significance in orchestrating metabolic flux and maintaining cellular energy balance. PFKM Protein, Human (HEK293, His) is the recombinant human-derived PFKM protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P76761
    CaMKII alpha/CAMK2A Protein, Human (sf9, GST)

    Calcium/calmodulin-dependent protein kinase type II subunit alpha; CAMKA

    Human Sf9 insect cells
    CaMKII α/CAMK2A protein functions autonomously upon Ca(2+)/calmodulin binding and autophosphorylation. CaMKII alpha/CAMK2A Protein, Human (sf9, GST) is the recombinant human-derived CaMKII alpha/CAMK2A protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of CaMKII alpha/CAMK2A Protein, Human (sf9, GST) is 478 a.a., with molecular weight of ~80 kDa.
  • HY-P70599
    PKM2 Protein, Human (530a.a, His)

    Pyruvate kinase PKM; CTHBP; OIP-3; THBP1

    Human E. coli
    PKM2 Protein, Human (530a.a, His) is a recombinant PKM2 protein with a His-Flag. PKM2 Protein is one of the rate-limiting enzymes in glycolysis.
  • HY-P73679
    RET Protein, Human (HEK293, His)

    Proto-oncogene tyrosine-protein kinase receptor Ret; RET; CDHF12; CDHR16

    Human HEK293
    RET protein is a receptor tyrosine protein kinase that plays a key role in cell proliferation, neuronal navigation, and differentiation upon binding to glial cell-derived neurotrophic factor family ligands. It regulates the delicate balance between cell death and survival, influences positional information, and is critical for intestinal organogenesis, enteric nervous system development, renal organogenesis, and Peyer's patch formation. RET Protein, Human (HEK293, His) is the recombinant human-derived RET protein, expressed by HEK293 , with N-His labeled tag. The total length of RET Protein, Human (HEK293, His) is 607 a.a., with molecular weight of 110-120 kDa.
  • HY-P74251
    Citrate Synthase/CS Protein, Human (sf9, His)

    Citrate synthase, mitochondrial; Citrate (Si)-synthase; CS

    Human Sf9 insect cells
    Citrate Synthase (CS) is a key enzyme in carbohydrate metabolism, specifically in the tricarboxylic acid (TCA) cycle, where it catalyzes the conversion of oxaloacetate and acetyl-CoA to form citrate. This enzymatic process represents the first and crucial step in the TCA cycle, which is fundamental to cellular energy production. By initiating the cycle and facilitating the condensation of acetyl-CoA with oxaloacetate, CS plays a central role in channeling metabolic intermediates towards the production of energy-rich molecules. This step not only generates citrate but also sets the stage for subsequent reactions in the TCA cycle, ultimately contributing to the efficient extraction of energy from carbohydrates and other metabolic substrates. The activity of CS is pivotal in maintaining cellular energy homeostasis and ensuring the proper functioning of aerobic metabolism. Citrate Synthase/CS Protein, Human (sf9, His) is the recombinant human-derived Citrate Synthase/CS protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Citrate Synthase/CS Protein, Human (sf9, His) is 439 a.a., with molecular weight of ~46 kDa.
  • HY-P71049
    PGK1 Protein, Human (HEK293, His)

    Phosphoglycerate kinase 1; Cell migration-inducing gene 10 protein; Primer recognition protein 2; PGK1; PGKA

    Human HEK293
    The PGK1 protein plays a key role in the glycolysis pathway by catalyzing one of two ATP-generating reactions, promoting the reversible conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate. In addition to its glycolytic function, PGK1 appears to act as a cofactor protein for polymerase α, playing a role in primer recognition. PGK1 Protein, Human (HEK293, His) is the recombinant human-derived PGK1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PGK1 Protein, Human (HEK293, His) is 416 a.a., with molecular weight of 46-50 kDa.
  • HY-P71132
    TGM2/Transglutaminase 2 Protein, Mouse (HEK293, His)

    Protein-glutamine gamma-glutamyltransferase 2; Tgm2; Tissue transglutaminase; Transglutaminase C; TGase-2

    Mouse HEK293
    The TGM2/transglutaminase 2 protein is a calcium-dependent acyltransferase involved in bone development, angiogenesis, wound healing, and apoptosis. TGM2 is also involved in neurotransmission-independent actions and serves as a signal transducer in α-1 adrenergic receptor-mediated pathways. TGM2/Transglutaminase 2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived TGM2/Transglutaminase 2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TGM2/Transglutaminase 2 Protein, Mouse (HEK293, His) is 685 a.a., with molecular weight of 70-90 kDa.
  • HY-P70012
    Thymidylate Protein, Human (HEK293, His)

    rHuThymidylate /kinaseDTYMK, His; Thymidylate kinase; dTMP kinase; DTYMK; CDC8; TMPK; TYMK

    Human HEK293
    Thymidylate proteins play a key role in DNA synthesis by catalyzing the phosphorylation of thymidine monophosphate (dTMP) to thymidine diphosphate (dTDP). This enzymatic process is critical for the production of dTDP, the direct precursor of the DNA building block dTTP. Thymidylate Protein, Human (HEK293, His) is the recombinant human-derived Thymidylate protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Thymidylate Protein, Human (HEK293, His) is 212 a.a., with molecular weight of ~26.0 kDa.
  • HY-P70146
    Ketohexokinase/KHK Protein, Human (HEK293, His)

    rHuKetohexokinase/KHK, His; Ketohexokinase; Hepatic fructokinase; KHK

    Human HEK293
    Ketohexokinase (KHK) proteins play a key role in carbohydrate metabolism by catalyzing the phosphorylation of ketoglycosides into fructose-1-phosphate. This enzyme activity is a key step in the utilization and processing of fructose within cells. Ketohexokinase/KHK Protein, Human (HEK293, His) is the recombinant human-derived Ketohexokinase/KHK protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Ketohexokinase/KHK Protein, Human (HEK293, His) is 298 a.a., with molecular weight of ~30.0 kDa.
Cat. No. Product Name Effect Purity