1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. PARP
  4. PARP1 Inhibitors

PARP1 Inhibitors

PARP

PARP1

PARP2

PARP3

PARP4

TNKS1/PARP5A

TNKS2/PARP5B

PARP10

PARP14

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform PARP1 together.

Please try each isoform separately.

PARP1 Specific Inhibitors
Product Name PARP1 PARP PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP10 PARP1 Selectivity Purity
Rucaparib phosphate
PARP-1, Ki: 1.4 nM
              Selective Inhibitor 99.89%
Rucaparib Camsylate
PARP-1, Ki: 1.4 nM
              Selective Inhibitor 99.92%
NMS-P118
PARP-1, Kd: 9 nM
 
PARP-2, Kd: 1390 nM
          Selective Inhibitor 99.08%
AG14361
PARP-1, Ki: 0.5 nM
              Selective Inhibitor 98.54%
Iniparib
PARP1
              Selective Inhibitor 99.65%
Talazoparib 8R,9S
PARP-1, IC50: 144 nM
              Selective Inhibitor 95.08%
Niraparib R-enantiomer
PARP-1, IC50: 2.4 nM
              Selective Inhibitor 99.37%
Rucaparib
PARP-1, Ki: 1.4 nM
              Selective Inhibitor
NMS-P515
PARP-1, Kd: 16 nM
PARP-1, IC50: 27 nM (in Hela cells)
              Selective Inhibitor
WD2000-012547
PARP-1, pKi: 8.221
              Selective Inhibitor
Olaparib
PARP-1, IC50: 5 nM
 
PARP-2, IC50: 1 nM
   
tankyrase-1, IC50: 1.5 μM
    Pan Inhibitor 99.98%
Talazoparib
PARP1, Ki: 1.2 nM
 
PARP2, Ki: 0.87 nM
          Pan Inhibitor 99.83%
XAV-939
ARTD1, IC50: 5500 nM
 
ARTD2, IC50: 479 nM
   
TNKS1, IC50: 5 nM
TNKS2, IC50: 2 nM
  Pan Inhibitor 98.04%
Niraparib
PARP-1, IC50: 3.8 nM
 
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
    Pan Inhibitor 99.93%
Veliparib
PARP-1, Ki: 5.2 nM
 
PARP-2, Ki: 2.9 nM
          Pan Inhibitor >98.0%
Niraparib tosylate
PARP-1, IC50: 3.8 nM
 
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
    Pan Inhibitor 99.52%
PJ34
PARP-1, IC50: 110 nM
PARP, IC50: 110 nM
PARP-2, IC50: 86 nM
          Pan Inhibitor >98.0%
AZD-2461
PARP1, IC50: 5 nM
 
PARP2, IC50: 2 nM
PARP3, IC50: 200 nM
        Pan Inhibitor 98.39%
A-966492
PARP-1, Ki: 1 nM
 
PARP-2, Ki: 1.5 nM
          Pan Inhibitor 98.59%
MN-64
ARTD1, IC50: 19.1 μM
 
ARTD2, IC50: 39.4 μM
   
TNKS1, IC50: 6 nM
TNKS2, IC50: 72 nM
  Pan Inhibitor 98.22%
ME0328
ARTD1/PARP1, IC50: 6.3 μM
 
ARTD2/PARP2, IC50: 10.8 μM
ARTD3/PARP3, IC50: 0.89 μM
 
ARTD5/TNKS1, IC50: 47.3 μM
ARTD6/TNKS2, IC50: 34.3 μM
ARTD10/PARP10, IC50: 71.3 μM
Pan Inhibitor 99.34%
UPF 1069
PARP-1, IC50: 8 μM
 
PARP-2, IC50: 0.3 μM
          Pan Inhibitor 98.88%
Niraparib hydrochloride
PARP-1, IC50: 3.8 nM
 
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
    Pan Inhibitor 99.80%
Paris saponin VII
PARP-1
              Pan Inhibitor