1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. PARP
  4. PARP1 Inhibitors

PARP1 Inhibitors

PARP

PARP1

PARP2

PARP3

PARP4

TNKS1/PARP5A

TNKS2/PARP5B

PARP10

PARP14

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform PARP1 together.

Please try each isoform separately.

PARP1 Specific Inhibitors & Activators
Product Name PARP1 PARP PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP10 PARP1 Selectivity Purity
Rucaparib phosphate
PARP-1, Ki: 1.4 nM
              Selective Inhibitor 99.89%
Rucaparib Camsylate
PARP-1, Ki: 1.4 nM
              Selective Inhibitor 99.92%
NMS-P118
PARP-1, Kd: 9 nM
 
PARP-2, Kd: 1390 nM
          Selective Inhibitor 99.80%
AG14361
PARP-1, Ki: 0.5 nM
              Selective Inhibitor 98.54%
Iniparib
PARP1
              Selective Inhibitor 99.87%
(8R,9S)-Talazoparib
PARP-1, IC50: 144 nM
              Selective Inhibitor 95.08%
Niraparib R-enantiomer
PARP-1, IC50: 2.4 nM
              Selective Inhibitor 99.37%
Rucaparib
PARP-1, Ki: 1.4 nM
              Selective Inhibitor
NMS-P515
PARP-1, Kd: 16 nM
PARP-1, IC50: 27 nM (in Hela cells)
              Selective Inhibitor
PROTAC PARP1 degrader
PARP1
              Selective Inhibitor
WD2000-012547
PARP-1, pKi: 8.221
              Selective Inhibitor
Olaparib
PARP-1, IC50: 5 nM
 
PARP-2, IC50: 1 nM
   
tankyrase-1, IC50: 1.5 μM
    Pan Inhibitor 99.98%
Talazoparib
PARP1, Ki: 1.2 nM
 
PARP2, Ki: 0.87 nM
          Pan Inhibitor 99.89%
Niraparib
PARP-1, IC50: 3.8 nM
 
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
    Pan Inhibitor 99.97%
XAV-939
ARTD1, IC50: 5500 nM
 
ARTD2, IC50: 479 nM
   
TNKS1, IC50: 5 nM
TNKS2, IC50: 2 nM
  Pan Inhibitor 98.71%
Veliparib
PARP-1, Ki: 5.2 nM
 
PARP-2, Ki: 2.9 nM
          Pan Inhibitor >98.0%
Niraparib tosylate
PARP-1, IC50: 3.8 nM
 
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
    Pan Inhibitor 99.52%
PJ34 hydrochloride
PARP-1, IC50: 110 nM
PARP, IC50: 110 nM
PARP-2, IC50: 86 nM
          Pan Inhibitor 97.68%
PJ34
PARP-1, IC50: 110 nM
PARP, IC50: 110 nM
PARP-2, IC50: 86 nM
          Pan Inhibitor >98.0%
A-966492
PARP-1, Ki: 1 nM
 
PARP-2, Ki: 1.5 nM
          Pan Inhibitor 98.59%
AZD-2461
PARP1, IC50: 5 nM
 
PARP2, IC50: 2 nM
PARP3, IC50: 200 nM
        Pan Inhibitor 98.39%
MN-64
ARTD1, IC50: 19.1 μM
 
ARTD2, IC50: 39.4 μM
   
TNKS1, IC50: 6 nM
TNKS2, IC50: 72 nM
  Pan Inhibitor 98.22%
ME0328
ARTD1/PARP1, IC50: 6.3 μM
 
ARTD2/PARP2, IC50: 10.8 μM
ARTD3/PARP3, IC50: 0.89 μM
 
ARTD5/TNKS1, IC50: 47.3 μM
ARTD6/TNKS2, IC50: 34.3 μM
ARTD10/PARP10, IC50: 71.3 μM
Pan Inhibitor 99.34%
Niraparib hydrochloride
PARP-1, IC50: 3.8 nM
 
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
    Pan Inhibitor 99.80%
UPF 1069
PARP-1, IC50: 8 μM
 
PARP-2, IC50: 0.3 μM
          Pan Inhibitor 98.88%
Paris saponin VII
PARP-1
              Pan Inhibitor
Verminoside
PARP-1
              default Activator