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  4. Cucurbitaceae

Cucurbitaceae

 

Cucurbitaceae (208):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0890
    Tubeimoside I 102040-03-9 99.96%
    Tubeimoside I is an orally active HSPD1 inhibitor. Tubeimoside I inhibits NF-κB, MAPK, as well as regulates eNOS-VEGF. Tubeimoside I induces cytoprotective Autophagy via an Akt-mediated pathway. Tubeimoside I inhibits proinflammatory cytokine (IL-6 and IL-1β) production. Tubeimoside I exhibits anti-inflammatory activities. Tubeimoside I promotes angiogenesis and improves sepsis symptoms. Tubeimoside I is used in the research of inflammatory diseases, various cancers, sepsis and ischemic diseases.
    Tubeimoside I
  • HY-N0416
    Cucurbitacin B 6199-67-3 99.81%
    Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity.
    Cucurbitacin B
  • HY-N1405
    Cucurbitacin I 2222-07-3 99.56%
    Cucurbitacin I is a natural selective inhibitor of JAK2/STAT3, with potent anti-cancer activity.
    Cucurbitacin I
  • HY-N0502
    Mogroside V 88901-36-4 99.76%
    Mogroside V is a the major active constituent of a traditional Chinese medicine Siraitiae Fructus. Mogroside V reduces the intracellular reactive oxygen species (ROS) levels and enhances mitochondrial function. Mogroside V has anti-oxidative, anti-diabetic and anti-carcinogenic effects. Mogroside V can be used for diabetic diseases research.
    Mogroside V
  • HY-W017782
    2,5-Furandimethanol 1883-75-6 99.71%
    2,5-Furandimethanol (2,5-Bis(hydroxymethyl)furan) is a building block for the enzymatic synthesis of bio-based polyesters. 2,5-Furandimethanol is also a metabolite of Phellinus linteus. 2,5-Furandimethanol affects leukemia. 2,5-Furandimethanol can be used in fungal infection research.
    2,5-Furandimethanol
  • HY-N15682
    13-cis-β-Carotene 6811-73-0
    13-cis-β-Carotene ((7Z)-Provitamin A; (7Z)-beta-Carotene) is a provitamin A carotenoid isomer found in leaves, flowers, stems, and fruit of Momordica charantia. 13-cis-β-Carotene undergoes nonenzymatic isomerization to other β-carotene isomers during aerobic incubation, extraction, and analysis. 13-cis-β-Carotene can be used for the research of chronic diseases.
    13-cis-β-Carotene
  • HY-N19707
    7β-Hydroxykaurenolide 5691-63-4
    7β-Hydroxykaurenolide is a kaurenolide and by-product of Gibberellin biosynthesis, can be found in Gibberella fujikuroi cultures. 7β-Hydroxykaurenolide is a drug intermediate.
    7β-Hydroxykaurenolide
  • HY-N17993
    GypenosideZ-1 862286-49-5
    GypenosideZ-1 is a triterpenoid saponin found in Gynostemma pentaphyllum.
    GypenosideZ-1
  • HY-N8211
    Gypenoside L 94987-09-4 99.89%
    Gypenoside L is a saponin that can be found in Gynostemma pentaphyllum. Gypenoside L increases the SA-β-galactosidase activity, promotes the production of senescence-associated secretory cytokines. Gypenoside L also can activate p38 and ERK MAPK pathways and NF-κB pathway to induce senescence. Gypenoside L exhibits anti-tumor and anti-inflammatory activities.
    Gypenoside L
  • HY-N0417
    Cucurbitacin E 18444-66-1 99.92%
    Cucurbitacin E is a CDK1 inhibitor that significantly inhibits the activity of the cyclin B1/CDC2 complex. Cucurbitacin E also induces PANoptosis in adrenocortical carcinoma cells in a ZBP1-dependent manner. Cucurbitacin E exhibits synergistic effects with Mitotane (HY-13690); when used in combination, they effectively eliminate tumors.
    Cucurbitacin E
  • HY-N1990
    Gypenoside XLIX 94987-08-3 99.88%
    Gypenoside XLIX is a multifunctional bioactive compound that can be isolated from Gynostemma pentaphyllum, with a Ka value of 1.58 μM for its binding to SIRT1. Gypenoside XLIX acts as a PPAR-α agonist. It inhibits the activation of TLR4-mediated NF-κB signaling pathway by activating the Sirt1/Nrf2 signaling pathway, reduces ROS accumulation, and alleviates hepatic inflammatory injury in mice with sepsis-induced liver disease. Gypenoside XLIX targets SIRT1 to block YAP-NLRP3 activation and improve sepsis-induced cardiomyopathy. Gypenoside XLIX inhibits apoptosis (Apoptosis), pyroptosis (Pyroptosis), autophagy (Autophagy), lipid peroxidation, pro-inflammatory cytokines and anti-inflammatory cytokines. Gypenoside XLIX alleviates sepsis-induced splenic injury by inhibiting inflammation and oxidative stress, and mitigates sepsis-associated encephalopathy by targeting PPAR-α. Gypenoside XLIX prevents acute kidney injury by inhibiting IGFBP7/IGF1R-mediated programmed cell death and inflammation. Gypenoside XLIX inhibits the expression and activity of vascular cell adhesion molecule-1 in cytokine-induced human endothelial cells. Gypenoside XLIX is applicable to research related to acute liver injury, lung injury, cardiomyopathy, acute splenic injury, sepsis-associated encephalopathy, acute kidney injury, atherosclerosis and chronic inflammation.
    Gypenoside XLIX
  • HY-N2312
    Mogrol 88930-15-8 99.76%
    Mogrol is a biometabolite of mogrosides, and acts via inhibition of the ERK1/2 and STAT3 pathways, or reducing CREB activation and activating AMPK signaling.
    Mogrol
  • HY-N0553
    Gypenoside XVII 80321-69-3 99.69%
    Gypenoside XVII, a novel phytoestrogen belonging to the gypenosides, can activate estrogen receptors.
    Gypenoside XVII
  • HY-N1986
    Cucurbitacin D 3877-86-9 99.93%
    Cucurbitacin D is the active ingredient in Trichosanthes kirilowii and can disrupt the interaction between Hsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D is an inflammasome activator. Cucurbitacin D induces cell cycle arrest and cell apoptosis, exhibiting anti-tumor and anti-inflammatory effects.
    Cucurbitacin D
  • HY-N2440
    Gypenoside A 157752-01-7 99.79%
    Gypenoside A is an orally active triterpenoid compound that can be isolated from Gynostemma pentaphyllum. Gypenoside A has anti-inflammatory and antioxidant activities. Gypenoside A also has a certain protective effect on cardiomyocytes and can inhibit apoptosis. Gypenoside A can be used in the research of cardiovascular diseases and inflammation-related diseases.
    Gypenoside A
  • HY-N2542
    Tubeimoside III 115810-13-4 99.91%
    Tubeimoside III is a triterpenoid saponin. Tubeimoside III has anti-inflammatory and antitumor effects. Tubeimoside III has an LD50 of 15 mg/kg by intraperitoneal injection in ICR mice. Tubeimoside III can be used for the research of tumors and inflammatory diseases.
    Tubeimoside III
  • HY-N2456
    Mogroside IV-E 88915-64-4 99.71%
    Mogroside IV-E, a triterpenoid glycoside, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities.
    Mogroside IV-E
  • HY-N6942
    Mogroside IV-A 88901-41-1 99.9%
    Mogroside IV-A, a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities.
    Mogroside IV-A
  • HY-N1932
    Bayogenin 6989-24-8 99.90%
    Bayogenin is a triterpenoid saponin and one of the main components of Medicago sativa saponins. Bayogenin is an inhibitor of glycogen phosphorylase.
    Bayogenin
  • HY-N6814
    Mogroside IIe 88901-38-6 99.95%
    Mogroside IIe is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities.
    Mogroside IIe