1. Cell Cycle/DNA Damage
  2. PPAR
  3. Gypenoside XLIX

Gypenoside XLIX 

Cat. No.: HY-N1990 Purity: 99.35%
Handling Instructions

Gypenoside XLIX, a dammarane-type glycoside, is a prominent component of G. pentaphyllum. Gypenoside XLIX is a selective peroxisome proliferator-activated receptor (PPAR)-alpha activator and inhibits cytokine-induced vascular cell adhesion molecule-1 (VCAM-1) overexpression and hyperactivity in human endothelial cells.

For research use only. We do not sell to patients.

Gypenoside XLIX Chemical Structure

Gypenoside XLIX Chemical Structure

CAS No. : 94987-08-3

Size Price Stock Quantity
5 mg USD 80 In-stock
Estimated Time of Arrival: December 31
10 mg USD 140 In-stock
Estimated Time of Arrival: December 31
20 mg USD 230 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Gypenoside XLIX, a dammarane-type glycoside, is a prominent component of G. pentaphyllum. Gypenoside XLIX is a selective peroxisome proliferator-activated receptor (PPAR)-alpha activator and inhibits cytokine-induced vascular cell adhesion molecule-1 (VCAM-1) overexpression and hyperactivity in human endothelial cells[1].

IC50 & Target[1]

PPAR-α

 

Molecular Weight

1047.23

Formula

C₅₂H₈₆O₂₁

CAS No.

94987-08-3

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (119.36 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9549 mL 4.7745 mL 9.5490 mL
5 mM 0.1910 mL 0.9549 mL 1.9098 mL
10 mM 0.0955 mL 0.4775 mL 0.9549 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 6.25 mg/mL (5.97 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 6.25 mg/mL (5.97 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 6.25 mg/mL (5.97 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.35%

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Keywords:

Gypenoside XLIXPPARPeroxisome proliferator-activated receptorsInhibitorinhibitorinhibit

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Product Name:
Gypenoside XLIX
Cat. No.:
HY-N1990
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