1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. PPAR
  4. PPAR Isoform

PPAR

 

PPAR Related Products (83):

Cat. No. Product Name Effect Purity
  • HY-N0182
    Fisetin
    Inhibitor 98.87%
    Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects.
  • HY-15721
    FH535
    Inhibitor 99.87%
    FH535 is an inhibitor of Wnt/β-catenin and PPAR, with anti-tumor activities.
  • HY-14166
    MK-886
    Antagonist 99.74%
    MK-886 (L 663536) is a potent, cell-permeable and orally active FLAP (IC50 of 30 nM) and leukotriene biosynthesis (IC50s of 3 nM and 1.1 μM in intact leukocytes and human whole blood, respectively) inhibitor.
  • HY-12377
    GSK0660
    Antagonist 99.55%
    GSK0660 is a potent antagonist of PPARβ and PPARδ, with IC50s of both 155 nM, and is nearly inactive on PPARα and PPARγ with IC50s of both >10 μM.
  • HY-145804
    AZD-9574
    Inhibitor 99.11%
    AZD-9574 is a potent and brain penetrant PARP1 inhibitor and shows >8000-fold selectivity for PARP1 compared to PARP2/3/5a/6.
  • HY-139040
    2-(Tetradecylthio)acetic acid
    Activator ≥98.0%
    2-Tetradecylthio acetic acid is a pan-peroxisome proliferator activated receptor (pan-PPAR) activator.
  • HY-100348
    EPI-001
    Modulator 98.87%
    EPI-001, a selective inhibitor of Androgen Receptor (AR), targets transactivation unit 5 (Tau-5) of the AR.
  • HY-50665
    LY518674
    Antagonist 98.75%
    LY518674 is a potent, selective PPARα antagonist, with an EC50 of 42 nM for human PPARα.
  • HY-17444
    Tesaglitazar
    Agonist 98.09%
    Tesaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist that is more potent on PPARγ than on PPARα, with EC50s of 13.4 μM and 3.6 μM for rat PPARα and human PPARα, respectively, and approximately 0.2 μM for both rat and human PPARγ.
  • HY-B1415
    Clofibric acid
    Agonist 99.77%
    Clofibric acid (Chlorofibrinic acid), the pharmaceutically active metabolite of lipid regulators Clofibrate, Etofibrate and Etofyllinclofibrate, is a PPARα agonist which exhibits hypolipidemic effects.
  • HY-Y0078
    Cinnamyl Alcohol
    Inhibitor ≥98.0%
    Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, with anti-obesity activity.
  • HY-122716
    PTGR2-IN-1
    99.93%
    PTGR2-IN-1 is a potent PTGR2 inhibitor with an IC50 of ~0.7 μM.
  • HY-W011220
    Ciglitazone
    Agonist 98.89%
    Ciglitazone is a potent and selective PPARγ agonist (EC50=3 μM).
  • HY-N3026
    Soyasaponin Ab
    Inhibitor 99.20%
    Soyasaponin Ab is a soyasaponin that exerts an anti-obesity effect in 3T3-L1 adipocytes through downregulation of peroxisome proliferator-activated receptor γ (PPARγ).
  • HY-134377
    Bocidelpar
    Modulator 98.09%
    Bocidelpar is a modulator of peroxisome proliferator-activated receptor delta (PPAR-δ).
  • HY-N6642
    Ankaflavin
    Agonist
    Ankaflavin, isolated from Monascus-Fermented red rice, is an orally active PPARγ agonist.
  • HY-N2453
    Convallatoxin
    Activator 98.66%
    Convallatoxin is a cardiac glycoside isolated from Adonis amurensis Regel et Radde.
  • HY-101676
    RG-12525
    Agonist 98.39%
    RG-12525 is a a specific, competitive and orally effective antagonist of the peptidoleukotrienes, LTC4, LTD4 and LTE4, inhibiting LTC4-, LTD4- and LTE4-inducd guinea pig parenchymal strips contractions, with IC50s of 2.6 nM, 2.5 nM and 7 nM, respectively; RG-12525 is also a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist with IC50 of appr 60 nM and a potent inhibitor of CYP3A4, with a Ki value of 0.5 µM.
  • HY-117727
    Leriglitazone
    Antagonist
    Leriglitazone (Hydroxypioglitazone), a metabolite of pioglitazone.
  • HY-14739
    Choline Fenofibrate
    Agonist 99.93%
    Choline Fenofibrate (ABT-335), a choline salt of Fenofibric acid (HY-B0760), releases free Fenofibric acid in the gastrointestinal tract.