CSNK1E/CK1e
Twin to CK1δ, casein kinase 1 epsilon (CK1ε, gene CSNK1E) shares the δ/ε branch of the CK1 family and phosphorylates circadian PER proteins, setting clock period and phase. Genetic studies link CSNK1E variation to diurnal preference and to bipolar or affective disorders, and CK1ε, like CK1δ, phosphorylates tau and α-synuclein, implicating it in neurodegeneration. The kinase is broadly expressed, associates with microtubules and the cytoskeleton, and participates in Wnt signaling and vesicular trafficking. CK1ε can be regulated by autophosphorylation of its C-terminal tail, which distinguishes its control from that of the constitutively active CK1α isoforms.
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CSNK1E/CK1e Recombinant Proteins (3)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
