1. Infection

Infection

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Infection Related Products (5534):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-17589A
    Chloroquine 54-05-7 99.98%
    Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis.
    Chloroquine
  • HY-10108
    LY294002 154447-36-6 ≥98.0%
    LY294002 is a broad-spectrum inhibitor of PI3K with IC50s of 0.5, 0.57, and 0.97 μM for PI3Kα, PI3Kδ and PI3Kβ, respectively[1].
    LY294002
  • HY-15142
    Doxorubicin hydrochloride 25316-40-9 ≥99.0%
    Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent.
    Doxorubicin hydrochloride
  • HY-100558
    Bafilomycin A1 88899-55-2 ≥99.0%
    Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H+-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg.
    Bafilomycin A1
  • HY-B1743A
    Puromycin dihydrochloride 58-58-2 ≥98.0%
    Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis[1].
    Puromycin dihydrochloride
  • HY-B0215
    Acetylcysteine 616-91-1 ≥98.0%
    Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus.
    Acetylcysteine
  • HY-14648
    Dexamethasone 50-02-2 99.86%
    Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist.
    Dexamethasone
  • HY-B0988
    Deferoxamine mesylate 138-14-7 ≥98.0%
    Deferoxamine mesylate (Deferoxamine B mesylate) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues.
    Deferoxamine mesylate
  • HY-15141
    Staurosporine 62996-74-1 ≥98.0%
    Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively.
    Staurosporine
  • HY-17561
    G-418 disulfate 108321-42-2 ≥98.0%
    G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes.
    G-418 disulfate
  • HY-10586
    5-Azacytidine 320-67-2 ≥98.0%
    5-Azacytidine (Azacitidine; 5-AzaC; Ladakamycin) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation.
    5-Azacytidine
  • HY-13629
    Etoposide 33419-42-0 ≥98.0%
    Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent.
    Etoposide
  • HY-100381
    Nigericin sodium salt 28643-80-3 ≥98.0%
    Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus that works by acting as an H+, K+, and Pb2+ ionophore, a NLRP3 activator[1].
    Nigericin sodium salt
  • HY-N0565B
    Doxycycline (hyclate) 24390-14-5 ≥98.0%
    Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor[1].
    Doxycycline (hyclate)
  • HY-16592
    Brefeldin A 20350-15-6
    Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking.
    Brefeldin A
  • HY-Y0320
    Dimethyl sulfoxide 67-68-5 ≥99.0%
    Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves both polar and nonpolar compounds.
    Dimethyl sulfoxide
  • HY-16561
    Resveratrol 501-36-0 ≥98.0%
    Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties.
    Resveratrol
  • HY-A0098
    Tunicamycin 11089-65-9 ≥99.0%
    Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT).
    Tunicamycin
  • HY-A0281
    4-Phenylbutyric acid 1821-12-1 ≥98.0%
    4-Phenylbutyric acid (4-PBA) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research.
    4-Phenylbutyric acid
  • HY-B0490
    Hygromycin B 31282-04-9 ≥98.0%
    Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.
    Hygromycin B