1. Infection

Infection

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Infection Related Products (1556):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-12320
    Cycloheximide 66-81-9 99.86%
    Cycloheximide (Naramycin A) is an eukaryote protein synthesis inhibitor, with IC50s of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively.
    Cycloheximide
  • HY-100558
    Bafilomycin A1 88899-55-2 >99.0%
    Bafilomycin A1, a macrolide antibiotic isolated from the Streptomyces species, is a specific inhibitor of vacuolar-type H+ ATPase (V-ATPase). Bafilomycin A1 inhibits autophagy.
    Bafilomycin A1
  • HY-B1743A
    Puromycin Dihydrochloride 58-58-2 99.87%
    Puromycin Dihydrochloride (CL13900 dihydrochloride) is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibitsprotein synthesis.
    Puromycin Dihydrochloride
  • HY-N0565B
    Doxycycline (hyclate) 24390-14-5 99.19%
    Doxycycline (hyclate) (Doxycycline hydrochloride hemiethanolate hemihydrate), an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor.
    Doxycycline (hyclate)
  • HY-B0490
    Hygromycin B 31282-04-9 >98.00%
    Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.
    Hygromycin B
  • HY-17362
    Vancomycin hydrochloride 1404-93-9 98.83%
    Vancomycin hydrochloride is an antibiotic for the treatment of bacterial infections. It acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria. Vancomycin also alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis.
    Vancomycin hydrochloride
  • HY-B0221
    Amphotericin B 1397-89-3 >98.00%
    Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
    Amphotericin B
  • HY-13318
    Oseltamivir (acid) 187227-45-8 99.54%
    Oseltamivir acid (GS 4071), the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses.
    Oseltamivir (acid)
  • HY-B1370
    Hydroxychloroquine sulfate 747-36-4 99.99%
    Hydroxychloroquine sulfate is a synthetic antimalarial drug which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling.
    Hydroxychloroquine sulfate
  • HY-109025A
    Baloxavir 1985605-59-1 99.71%
    Baloxavir is an anti-influenza agent extracted from patent WO 2017104691 A1.
    Baloxavir
  • HY-B0470
    Neomycin sulfate 1405-10-3 >98.0%
    Neomycin sulfate is an aminoglycoside antibiotic used for preventing or treating bacterial infections.
    Neomycin sulfate
  • HY-B0522A
    Ampicillin sodium 69-52-3 >98.0%
    Ampicillin sodium is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.
    Ampicillin sodium
  • HY-16589
    Oligomycin A 579-13-5 99.94%
    Oligomycin A, created by Streptomyces, acts as a mitochondrial F0F1-ATPase inhibitor, with a Ki of 1 μM; Oligomycin A shows anti-fungal activity.
    Oligomycin A
  • HY-14879A
    Avibactam sodium 1192491-61-4 99.99%
    Avibactam sodium (NXL-104) is a covalent and reversible β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively.
    Avibactam sodium
  • HY-17409
    Nystatin 1400-61-9 98.29%
    Nystatin is a polyene antifungal antibiotic effective against yeast and mycoplasma.
    Nystatin
  • HY-13434
    Ionomycin 56092-81-0 >99.0%
    Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC).
    Ionomycin
  • HY-19930
    Vaborbactam 1360457-46-0 99.85%
    Vaborbactam is a cyclic boronic acid pharmacophore β-lactamase inhibitor.
    Vaborbactam
  • HY-B0272
    Rifampicin 13292-46-1 98.07%
    Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens.
    Rifampicin
  • HY-14434
    Asunaprevir 630420-16-5 99.74%
    Asunaprevir is a potent hepatitis C virus (HCV) NS3 protease inhibitor, with IC50 of 0.2 nM-3.5 nM.
    Asunaprevir
  • HY-13238
    Dolutegravir 1051375-16-6 99.95%
    Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM).
    Dolutegravir