1. Infection

Infection

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Infection Related Products (1040):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-12320
    Cycloheximide 66-81-9 99.45%
    Cycloheximide (Naramycin A) is an eukaryote protein synthesis inhibitor, with IC50s of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively.
    Cycloheximide
  • HY-100558
    Bafilomycin A1 88899-55-2 >99.0%
    Bafilomycin A1, a macrolide antibiotic isolated from the Streptomyces species, is a specific inhibitor of vacuolar-type H+ ATPase.
    Bafilomycin A1
  • HY-B1743A
    Puromycin Dihydrochloride 58-58-2 99.86%
    Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.
    Puromycin Dihydrochloride
  • HY-N0565B
    Doxycycline hyclate 24390-14-5 98.42%
    Doxycycline (hyclate) is a tetracycline antibiotic and broad-spectrum metalloproteinase (MMP) inhibitor.
    Doxycycline hyclate
  • HY-B0490
    Hygromycin B 31282-04-9 >98.00%
    Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.
    Hygromycin B
  • HY-13318
    Oseltamivir acid 187227-45-8 98.60%
    GS 4104, the ethyl ester prodrug of GS 4071, is an inhibitor of influenza virus neuraminidase with an IC50 of approximately 100 nM.
    Oseltamivir acid
  • HY-B0221
    Amphotericin B 1397-89-3 >98.00%
    Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
    Amphotericin B
  • HY-17362
    Vancomycin hydrochloride 1404-93-9 98.83%
    Vancomycin hydrochloride is an antibiotic for the treatment of bacterial infections. It acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria. Vancomycin also alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis.
    Vancomycin hydrochloride
  • HY-14879A
    Avibactam sodium 1192491-61-4 99.99%
    Avibactam sodium is a covalent and reversible β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively.
    Avibactam sodium
  • HY-14434
    Asunaprevir 630420-16-5 99.27%
    Asunaprevir is a potent hepatitis C virus (HCV) NS3 protease inhibitor, with IC50 of 0.2 nM-3.5 nM.
    Asunaprevir
  • HY-B0522A
    Ampicillin sodium 69-52-3 >98.0%
    Ampicillin sodium is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.
    Ampicillin sodium
  • HY-15005
    PSI-7977 1190307-88-0 99.95%
    PSI-7977 is an HCV RNA replication inhibitor with an EC50 of 92 nM.
    PSI-7977
  • HY-B0470
    Neomycin sulfate 1405-10-3 >98.0%
    Neomycin sulfate is an aminoglycoside antibiotic used for preventing or treating bacterial infections.
    Neomycin sulfate
  • HY-B0356
    Ciprofloxacin 85721-33-1 98.74%
    Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
    Ciprofloxacin
  • HY-17412
    Minocycline hydrochloride 13614-98-7 99.38%
    Minocycline hydrochloride is a broad-spectrum tetracycline antibiotic, acting by binding to the bacterial 30S ribosomal subunit and inhibiting protein synthesis.
    Minocycline hydrochloride
  • HY-17409
    Nystatin 1400-61-9
    Nystatin is a polyene antifungal antibiotic effective against yeast and mycoplasma.
    Nystatin
  • HY-13238
    Dolutegravir 1051375-16-6 99.54%
    Dolutegravir is a second-generation HIV integrase strand transfer inhibitor (INSTI) with an IC50 of 2.7 nM.
    Dolutegravir
  • HY-14881
    Bedaquiline 843663-66-1 99.93%
    Bedaquiline, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
    Bedaquiline
  • HY-B0974
    Methicillin sodium salt 132-92-3
    Meticillin sodium salt is a narrow-spectrum β-lactam antibiotic of the penicillin class, used to treat infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus.
    Methicillin sodium salt
  • HY-13637
    Ganciclovir 82410-32-0 >98.0%
    Ganciclovir is a potent inhibitor of viruses of the herpes family, including cytomegalovirus (CMV), with an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1).
    Ganciclovir