1. Signaling Pathways
  2. MAPK/ERK Pathway
  3. MEK
  4. MEK1 Inhibitors

MEK1 Inhibitors

MEK1

MEK2

MEK5

MEK

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform MEK1 together.

Please try each isoform separately.

MEK1 Specific Inhibitors & Antagonists
Product Name MEK1 MEK2 MEK MEK1 Selectivity Purity
PD0325901
MEK1, IC50: 0.33 nM
    Selective Inhibitor 99.95%
CHMFL-EGFR-202
MEK1, IC50: 161 nM
    Selective Inhibitor
Cobimetinib
MEK1, IC50: 4.2 nM
    Selective Inhibitor 99.38%
CI-1040
MEK1, IC50: 17 nM
    Selective Inhibitor 98.54%
Isorhamnetin
MEK1
    Selective Inhibitor 99.95%
GDC-0623
MEK1, Ki: 0.13 nM (+ATP)
    Selective Inhibitor 99.15%
APS-2-79
MEK1
    Selective Antagonist 99.31%
Cobimetinib hemifumarate
MEK1, IC50: 4.2 nM
    Selective Inhibitor 99.27%
PD98059
MEK1, IC50: 2-7 μM
MEK2, IC50: 50 μM
  Pan Inhibitor 99.33%
Trametinib
MEK1, IC50: 2 nM
MEK2, IC50: 2 nM
  Pan Inhibitor 99.44%
Trametinib DMSO solvate
MEK1, IC50: 2 nM
MEK2, IC50: 2 nM
  Pan Inhibitor 99.77%
Selumetinib
MEK1, IC50: 14 nM
 
MEK, IC50: 12 nM
Pan Inhibitor 99.87%
Pimasertib
MEK1
MEK2
  Pan Inhibitor 99.95%
Refametinib
MEK1, IC50: 19 nM
MEK2, IC50: 47 nM
  Pan Inhibitor 99.82%
SL327
MEK1, IC50: 180 nM
MEK2, IC50: 220 nM
  Pan Inhibitor >98.0%
RO4987655
MEK1, IC50: 5.2 nM
MEK2, IC50: 5.2 nM
  Pan Inhibitor 98.22%
AZD8330
MEK1, IC50: 7 nM
MEK2, IC50: 7 nM
  Pan Inhibitor 98.75%
Theaflavin 3,3'-digallate
MEK1
MEK2
  Pan Inhibitor