FGFR-4
FGFR4 is the principal receptor for the endocrine growth factor FGF19 and signals through the FGFR4-Klotho beta co-receptor complex on hepatocytes. The FGF19-FGFR4 axis suppresses bile acid synthesis by downregulating CYP7A1, and it also modulates glucose and lipid metabolism, making this pair a focus in metabolic liver disease. Constitutive pathway activation occurs in hepatocellular carcinoma, and FGFR4 overexpression or FGF19 amplification correlates with aggressive tumors; FGFR4 is additionally implicated in rhabdomyosarcoma, where the Gly388Arg polymorphism has been studied. Liver-selective FGFR4 inhibitors such as fisogatinib have entered clinical trials for HCC, and recombinant FGFR4 supports these drug-discovery efforts.
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FGFR-4 Recombinant Proteins (18)
FGFR-4 Protein, Human (HEK293, Fc)
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Art. -Nr.: HY-P73057
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Recept
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FGFR-4 Protein, Human (HEK293, His)
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Art. -Nr.: HY-P73059
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Recept
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FGFR-4 Protein, Mouse (HEK293, His-Fc)
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Art. -Nr.: HY-P73060
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Receptor; CD334 Antigen; Fibroblast Growth Factor Receptor; FGFR-4
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FGFR-4 Protein, Rat (HEK293, Fc, Solution)
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Art. -Nr.: HY-P73061
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Receptor; CD334 Antigen; Fibroblast Growth Factor Receptor; FGFR-4
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FGFR-4 Protein, Rat (HEK293, hFc)
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Art. -Nr.: HY-P73061A
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Receptor; CD334 Antigen; Fibroblast Growth Factor Receptor; FGFR-4
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FGFR-4 Protein, Human (Biotinylated, HEK293, His-Avi)
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Art. -Nr.: HY-P78127
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Recept
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FGFR-4 Protein, Human (Biotinylated, sf9, Avi)
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Art. -Nr.: HY-P702761
Reinheit: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Recept
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FGFR-4 Protein, Mouse (HEK293, His)
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Art. -Nr.: HY-P75191
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Recept
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FGFR-4 Protein, Rhesus Macaque (HEK293, His)
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Art. -Nr.: HY-P76929
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Recept
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FGFR-4 Protein, Rhesus Macaque (HEK293, Fc)
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Art. -Nr.: HY-P76928
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Receptor; CD334 Antigen; Fibroblast Growth Factor Receptor; FGFR-4
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FGFR-4 Protein, Human (Biotinylated, HEK293, His)
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Art. -Nr.: HY-P77549
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Recept
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FGFR-4 Protein, Human (HEK293, His-Avi)
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Art. -Nr.: HY-P78441
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Recept
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FGFR-4 Protein, Rat (HEK293, His)
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Art. -Nr.: HY-P75190
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Recept
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FGFR-4 Protein, Human (Active, V550L, sf9, His-GST)
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Art. -Nr.: HY-P705569
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Recept
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FGFR-4 Protein, Human (Active, V550M, sf9, His-GST)
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Art. -Nr.: HY-P705836
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Recept
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FGFR-4 Protein, Human (Active, sf9)
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Art. -Nr.: HY-P705837
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Recept
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FGFR-4 Protein, Human (Active, C552S, sf9, His-GST)
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Art. -Nr.: HY-P706055
Reinheit: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Receptor; CD334 Antigen; Fibroblast Growth Factor Receptor; FGFR-4
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FGFR-4 Protein, Human (Active, V550E, sf9, His-GST)
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Art. -Nr.: HY-P706056
Reinheit: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: FGFR4; Receptor Protein-Tyrosine Kinase; Fibroblast Growth Factor Receptor 4; Hydroxyaryl-Protein Kinase; JTK2; Protein-Tyrosine Kinase; TKF; Soluble FGFR4 Variant 1; CD334; Tyrosylprotein Kinase; Tyrosine Kinase Related To Fibroblast Growth Factor Receptor; CD334 Antigen; Fibroblast Growth Factor Receptor; FGFR-4
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
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Capetin (28-54), human
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Synonyms: Serpin B6; Cytoplasmic Antiproteinase; cap; Peptidase Inhibitor
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
