1. Oligonucleotides
  2. Nucleoside Phosphoramidites

Nucleoside Phosphoramidites

Nucleoside phosphoramidites are derivatives of natural or synthetic nucleosides and are used to synthesize oligonucleotides, relatively short fragments of nucleic acid and their analogs. Nucleoside phosphoramidites were first introduced in 1981 by Beaucage and Caruthers. These nucleoside phosphoramidites permit the sequential addition of new bases to the DNA chain in an exquisitely simple and exceptionally efficient cyclic reaction. A standard phosphoramidite molecule contains a phosphite instead of the typical phosphate in nucleotides, as well as four specific protecting groups. These groups provide stable protection, but can be easily removed when necessary.

Nucleoside Phosphoramidites (30):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W013059
    DMT-dA(bz) Phosphoramidite 98796-53-3 99.00%
    DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA.
    DMT-dA(bz) Phosphoramidite
  • HY-W008848
    DMT-dG(ib) Phosphoramidite 93183-15-4 99.71%
    DMT-dG(ib) Phosphoramidite is typically used in the synthesis of DNA.
    DMT-dG(ib) Phosphoramidite
  • HY-W006102
    Bz-rA Phosphoramidite 104992-55-4
    Bz-rA Phosphoramidite is used for ribonucleotides modification.
    Bz-rA Phosphoramidite
  • HY-W013068
    DMT-dT Phosphoramidite 98796-51-1 98.74%
    DMT-dT Phosphoramidite is typically used in the synthesis of DNA.
    DMT-dT Phosphoramidite
  • HY-45492
    DMT-2'Fluoro-DG(IB) Amidite 144089-97-4 99.45%
    DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be used in the preparation of 4'-modified 2'-deoxy-2'-fluorouridine.
    DMT-2'Fluoro-DG(IB) Amidite
  • HY-D1411
    DMTr-4'-CF3-5-Me-U-CED phosphoramidite
    DMTr-4'-CF3-5-Me-U-CED phosphoramidite (DMTr-4'-CF3-5-Methyluridine-CED phosphoramidite), the modified oligodeoxynucleotide (ODN), is a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics.
    DMTr-4'-CF3-5-Me-U-CED phosphoramidite
  • HY-D1409
    DMTr-4'-F-U-CED-TBDMS phosphoramidite
    DMTr-4'-F-U-CED-TBDMS phosphoramidite (DMTr-4'-F-uridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-F-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure.
    DMTr-4'-F-U-CED-TBDMS phosphoramidite
  • HY-D1408
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite 1260508-74-4
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite (DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-Me-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure.
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite
  • HY-W008849
    DMT-dC(bz) Phosphoramidite 102212-98-6 99.70%
    DMT-dC(bz) Phosphoramidite is typically used in the synthesis of DNA.
    DMT-dC(bz) Phosphoramidite
  • HY-138580
    2'-OMe-A(Bz) Phosphoramidite 110782-31-5 98.59%
    2'-OMe-A(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.
    2'-OMe-A(Bz) Phosphoramidite
  • HY-W006103
    I-bu-rG Phosphoramidite 147201-04-5 ≥98.0%
    I-bu-rG Phosphoramidite is a phosphinamide monomer which can be used in the synthesis of nucleotides and nucleic acids.
    I-bu-rG Phosphoramidite
  • HY-21997
    Dmt-2'fluoro-da(bz) amidite 136834-22-5
    Dmt-2'fluoro-da(bz) amidite, an uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotide, is a nuclease-resistant antisense compound with high affinity and specificity for RNA targets. Dmt-2'fluoro-da(bz) amidite is also an intermediate for 5’-DMT-3’-phosphoramidite synthesis.
    Dmt-2'fluoro-da(bz) amidite
  • HY-138584
    IBU-DC Phosphoramidite 110522-84-4
    IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.
    IBU-DC Phosphoramidite
  • HY-111531
    DMTr-LNA-5MeU-3-CED-phosphoramidite 206055-75-6
    DMTr-LNA-5MeU-3-CED-phosphoramidite is a nucleoside derivative.
    DMTr-LNA-5MeU-3-CED-phosphoramidite
  • HY-138582
    N6-Methyl-dA phosphoramidite 105931-58-6
    N6-Methyl-dA phosphoramidite can be used in the synthesis of oligodeoxyribonucleotides.
    N6-Methyl-dA phosphoramidite
  • HY-138583
    Ac-dA Phosphoramidite 1027734-01-5
    Ac-dA Phosphoramidite is a phosphinamide monomer that can be used in the preparation of oligonucleotides.
    Ac-dA Phosphoramidite
  • HY-138579
    2'-OMe-G(ibu) Phosphoramidite 150780-67-9 98.89%
    2'-OMe-G(ibu) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.
    2'-OMe-G(ibu) Phosphoramidite
  • HY-137576
    DMT-dI Phosphoramidite 141684-35-7 98.15%
    Phosphoramidite is a modified phosphoramidite monomer used for the oligonucleotide synthesis.
    DMT-dI Phosphoramidite
  • HY-138586
    DMT-dC(ac) Phosphoramidite 154110-40-4 98.16%
    DMT-dC(ac) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.
    DMT-dC(ac) Phosphoramidite
  • HY-138578
    2'-O-Me-C(Bz) Phosphoramidite 110764-78-8 99.05%
    2'-O-Me-C(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.
    2'-O-Me-C(Bz) Phosphoramidite