Nucleoside Phosphoramidites

Nucleoside phosphoramidites are derivatives of natural or synthetic nucleosides and are used to synthesize oligonucleotides, relatively short fragments of nucleic acid and their analogs. Nucleoside phosphoramidites were first introduced in 1981 by Beaucage and Caruthers. These nucleoside phosphoramidites permit the sequential addition of new bases to the DNA chain in an exquisitely simple and exceptionally efficient cyclic reaction. A standard phosphoramidite molecule contains a phosphite instead of the typical phosphate in nucleotides, as well as four specific protecting groups. These groups provide stable protection, but can be easily removed when necessary.

Nucleoside Phosphoramidites (192):

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

HY-W008662

2'-Deoxy-5'-O-DMT-2'-fluorouridine	146954-74-7	99.94%
2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity.

HY-21242

MMT-Hexylaminolinker Phosphoramidite	114616-27-2	≥98.0%
MMT-Hexylaminolinker Phosphoramidite is a cleavable linker. MMT-Hexylaminolinker Phosphoramidite can be used to syntheses oligonucleotide gapmers or other nucleic acid molecules.

HY-45409

DMT-2′Fluoro-dU Phosphoramidite 146954-75-8 98.83%

DMT-2′Fluoro-dU Phosphoramidite could be used for nucleoside modification.
HY-W570886

2'-O-MOE-U 163759-97-5

2'-O-MOE-U is a phosphoramidite, can be used for oligonucleotide synthesis.
HY-138610

5'-O-DMT-Bz-rC 81246-76-6 99.69%

5'-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.
HY-W013059

DMT-dA(bz) Phosphoramidite 98796-53-3 99.78%

DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA.
HY-W013068

DMT-dT Phosphoramidite 98796-51-1 98.74%

DMT-dT Phosphoramidite is typically used in the synthesis of DNA.
HY-138586

DMT-dC(ac) Phosphoramidite 154110-40-4 99.76%

DMT-dC(ac) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.

DMT-2′Fluoro-dU Phosphoramidite	146954-75-8	98.83%
DMT-2′Fluoro-dU Phosphoramidite could be used for nucleoside modification.

2'-O-MOE-U	163759-97-5
2'-O-MOE-U is a phosphoramidite, can be used for oligonucleotide synthesis.

5'-O-DMT-Bz-rC	81246-76-6	99.69%
5'-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.

DMT-dA(bz) Phosphoramidite	98796-53-3	99.78%
DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA.

DMT-dT Phosphoramidite	98796-51-1	98.74%
DMT-dT Phosphoramidite is typically used in the synthesis of DNA.

DMT-dC(ac) Phosphoramidite	154110-40-4	99.76%
DMT-dC(ac) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.

HY-21997

DMT-2'fluoro-da(bz) amidite	136834-22-5	99.15%
Dmt-2'fluoro-da(bz) amidite, an uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotide, is a nuclease-resistant antisense compound with high affinity and specificity for RNA targets. Dmt-2'fluoro-da(bz) amidite is also an intermediate for 5’-DMT-3’-phosphoramidite synthesis.

HY-21545

5'-O-DMT-Bz-rA 81246-82-4 ≥98.0%

5'-O-DMT-Bz-rA is an intermediate for cyclic di-nucleotide compounds synthesis.

5'-O-DMT-Bz-rA	81246-82-4	≥98.0%
5'-O-DMT-Bz-rA is an intermediate for cyclic di-nucleotide compounds synthesis.

HY-W010702

5'-O-DMT-N2-ibu-dG	68892-41-1	≥98.0%
5'-O-DMT-N2-ibu-dG (N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine) is a deoxynucleoside which can be used in the preparation of oligonucleotides.

HY-W013077

N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine 64325-78-6 ≥98.0%

N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine can be used as an intermediate.
HY-W570885

2'-O-MOE-rC 251647-54-8 ≥98.0%

2'-O-MOE-rC is a 2'-O-MOE modified nucleoside. 2'-O-MOE-rC can be used for synthesis of DNA.

N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine	64325-78-6	≥98.0%
N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine can be used as an intermediate.

2'-O-MOE-rC	251647-54-8	≥98.0%
2'-O-MOE-rC is a 2'-O-MOE modified nucleoside. 2'-O-MOE-rC can be used for synthesis of DNA.

HY-46317

DMT-5Me-dC(Bz)-CE Phosphoramidite	105931-57-5	98.36%
DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding.

HY-148506

5'-ODMT cEt m5U Phosphoramidite (Amidite)	1197033-22-9	99.25%
5'-ODMT cEt m5U Phosphoramidite Amidite is a locked nucleic acid (LNA) analog. 5'-ODMT cEt m5U Phosphoramidite Amidite shows excellent safety and antisense activity.

HY-148505

5'-ODMT cEt N-Bzm5 C Phosphoramidite (Amidite)	1197033-17-2	99.17%
5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite is a potent nucleic acid analog. 5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite blongs to modified antisense oligonucleotide.

HY-138607

5'-O-DMT-N2-DMF-dG 40094-22-2 99.09%

5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
HY-138601

5'-O-DMT-N4-Bz-5-Me-dC 104579-03-5 98.72%

5'-O-DMT-N4-Bz-5-Me-dC is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
HY-138608

5'-O-DMT-rI 119898-59-8 99.17%

5'-O-DMT-Ri can be used in the synthesis of oligoribonucleotides.
HY-138614

5'-O-DMT-2'-O-TBDMS-Ac-rC 121058-85-3 99.80%

5'-O-DMT-2'-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.

Name
Email *

	Sorry, but the email address you supplied was invalid.