5'(E)-VP-2'-OMe-U phosphoramidite
Based on 1 Customer Validation
5'(E)-VP-2'-OMe-U Phosphoramidite is a phosphoramidite nucleotide precursor compound, mainly used to synthesize stable and functionalized modified oligonucleotides for the research and synthesis of nucleic acid drugs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 2172373-55-4
- Formula: C32H52N4O13P2
- Molecular Weight:762.72
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
All DNA/RNA Synthesis Isoforms
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Biological Activity
5'(E)-VP-2'-OMe-U phosphoramidite is a modified phosphoramidite monomer that can be used for the synthesis of oligonucleotides.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2172373-55-4
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Appearance Solid
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Molecular Weight 762.72
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Formula C32H52N4O13P2
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Color White to off-white
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SMILES
CO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](/C=C/P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)O[C@H]1N2C=CC(NC2=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (131.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (252 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3111 mL | 6.5555 mL | 13.1110 mL | 32.7774 mL |
| 5 mM | 0.2622 mL | 1.3111 mL | 2.6222 mL | 6.5555 mL | |
| 10 mM | 0.1311 mL | 0.6555 mL | 1.3111 mL | 3.2777 mL | |
| 15 mM | 0.0874 mL | 0.4370 mL | 0.8741 mL | 2.1852 mL | |
| 20 mM | 0.0656 mL | 0.3278 mL | 0.6555 mL | 1.6389 mL | |
| 25 mM | 0.0524 mL | 0.2622 mL | 0.5244 mL | 1.3111 mL | |
| 30 mM | 0.0437 mL | 0.2185 mL | 0.4370 mL | 1.0926 mL | |
| 40 mM | 0.0328 mL | 0.1639 mL | 0.3278 mL | 0.8194 mL | |
| 50 mM | 0.0262 mL | 0.1311 mL | 0.2622 mL | 0.6555 mL | |
| 60 mM | 0.0219 mL | 0.1093 mL | 0.2185 mL | 0.5463 mL | |
| 80 mM | 0.0164 mL | 0.0819 mL | 0.1639 mL | 0.4097 mL | |
| 100 mM | 0.0131 mL | 0.0656 mL | 0.1311 mL | 0.3278 mL |