2. Ligand for E3 Ligase

Ligand for E3 Ligase

The PROTAC molecule consists of a ligand, which binds an E3 ubiquitin ligase, connected by a linker to another ligand that binds the target protein.

The association between a protein and an E3 ligase, as induced by a PROTAC molecule, will lead to the transfer of ubiquitin and degradation of the targeted protein.

Ligand for E3 Ligase Related Products (9):

Cat. No. Product Name Effect Purity
  • HY-42424
    E3 ligase Ligand 1 98.19%
    E3 ligase Ligand 1 is a Ligand for E3 Ligase extracted from patent WO/2017/030814A1 compound example 202, used in PROTAC technology.
  • HY-103597
    E3 ligase Ligand 3 98.29%
    E3 ligase Ligand 3 is a ligand of E3 ligase, used in PROTAC technology.
  • HY-100947
    VH-298 99.32%
    VH-298 is a highly potent inhibitor of the VHL:HIF-α interaction with a Kd value of 80 to 90 nM, used in PROTAC technology.
  • HY-103596
    E3 ligase Ligand 2 99.60%
    E3 ligase Ligand 2 is a Ligand for E3 Ligase used in PROTAC technology.
  • HY-41547
    E3 ligase Ligand 4
    E3 ligase Ligand 4 is a ligand of E3 ligase, used in PROTAC technology.
  • HY-112275
    TNF-α-IN-1 is a TNF-α inhibitor extracted from patent US20030096841A1, compound example I-7.
  • HY-112078
    E3 ligase Ligand 1A
    E3 ligase Ligand 1A is a ligand of E3 ligase, used in PROTAC technology; E3 ligase Ligand 1A can be used in the research of cancer.
  • HY-U00425
    E3 ligase Ligand 5
    E3 ligase Ligand 5 is a ligand of E3 ligase, extracted from patent US 20160058872A1, Paragraph 0515. E3 ligase Ligand 5 can be used in PROTAC technology.
  • HY-110402
    Protein degrader 1 TFA
    Protein degrader 1 TFA is a small molecule ligand for VHL, an E3 ligase which has been targeted in numerous PROTACs.
Isoform Specific Products

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.