1. PROTAC
  2. Ligand for E3 Ligase
  3. VH032-cyclopropane-F

VH032-cyclopropane-F (Synonyms: VHL ligand 3; E3 ligase Ligand 19)

Cat. No.: HY-125905
Handling Instructions

VH032-cyclopropane-F is the VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein (e.g., SMARCA BD ligand) by a linker to form PROTACs (e.g., PROTAC 1). PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4。

For research use only. We do not sell to patients.

VH032-cyclopropane-F Chemical Structure

VH032-cyclopropane-F Chemical Structure

CAS No. : 2306193-99-5

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Description

VH032-cyclopropane-F is the VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein (e.g., SMARCA BD ligand) by a linker to form PROTACs (e.g., PROTAC 1). PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4[1]

IC50 & Target

VHL

 

Molecular Weight

532.63

Formula

C₂₆H₃₃FN₄O₅S

CAS No.

2306193-99-5

SMILES

O=C(NCC1=CC=C(C=C1O)C2=C(N=CS2)C)[[email protected]]3N(C[[email protected]@H](C3)O)C([[email protected]](C(C)(C)C)NC(C4(CC4)F)=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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VH032-cyclopropane-F
Cat. No.:
HY-125905
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