cIAP1 ligand 1
Based on 1 Customer Validation
cIAP1 ligand 1 is the LCL161 derivative based IAP ligand. cIAP1 ligand 1 can be connected to the ABL ligand for protein by a linker to form SNIPER. cIAP1 ligand 1 can be used in prostate cancer research.
For research use only. We do not sell to patients.
- Purity: 99.07%
- CAS No.: 2095244-42-9
- Formula: C31H42N4O6S
- Molecular Weight:598.75
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Anti-Cancer Compound Library
HY-L025
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Ubiquitination Compound Library
HY-L050
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Anti-Prostate Cancer Compound Library
HY-L124
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E3 Ligase Ligand Library
HY-L128
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Heterocyclic Compound Library
HY-L138
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MCE Bioactive Compound Library
HY-L001V
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High-Throughput Bioactive Compound Library
HY-L205
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Posttranslational Modification Library
HY-L226
Biological Activity
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cIAP1 |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2095244-42-9
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Appearance Solid
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Molecular Weight 598.75
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Formula C31H42N4O6S
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Color White to off-white
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SMILES
OC1=CC(C(C2=CSC([C@H]3N(CCC3)C([C@@H](NC([C@@H](N(C(OC(C)(C)C)=O)C)C)=O)C4CCCCC4)=O)=N2)=O)=CC=C1
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Synonyms
E3 ligase Ligand 12
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (167.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6701 mL | 8.3507 mL | 16.7015 mL | 41.7537 mL |
| 5 mM | 0.3340 mL | 1.6701 mL | 3.3403 mL | 8.3507 mL | |
| 10 mM | 0.1670 mL | 0.8351 mL | 1.6701 mL | 4.1754 mL | |
| 15 mM | 0.1113 mL | 0.5567 mL | 1.1134 mL | 2.7836 mL | |
| 20 mM | 0.0835 mL | 0.4175 mL | 0.8351 mL | 2.0877 mL | |
| 25 mM | 0.0668 mL | 0.3340 mL | 0.6681 mL | 1.6701 mL | |
| 30 mM | 0.0557 mL | 0.2784 mL | 0.5567 mL | 1.3918 mL | |
| 40 mM | 0.0418 mL | 0.2088 mL | 0.4175 mL | 1.0438 mL | |
| 50 mM | 0.0334 mL | 0.1670 mL | 0.3340 mL | 0.8351 mL | |
| 60 mM | 0.0278 mL | 0.1392 mL | 0.2784 mL | 0.6959 mL | |
| 80 mM | 0.0209 mL | 0.1044 mL | 0.2088 mL | 0.5219 mL | |
| 100 mM | 0.0167 mL | 0.0835 mL | 0.1670 mL | 0.4175 mL |
cIAP1 ligand 1 Related Classifications
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