1. Signaling Pathways
  2. PROTAC
  3. Ligands for E3 Ligase
  4. Cereblon Isoform

Cereblon

 

Cereblon Related Products (35):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-A0003
    Lenalidomide 191732-72-6 99.91%
    Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue.
    Lenalidomide
  • HY-10984
    Pomalidomide 19171-19-8 99.85%
    Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue.
    Pomalidomide
  • HY-130800
    Eragidomide 1860875-51-9 99.65%
    Eragidomide (CC-90009) is a first-in-class GSPT1-selective cereblon (CRBN) E3 ligase modulator, acts as a molecular glue.
    Eragidomide
  • HY-23095
    Thalidomide-5-OH 64567-60-8 98.07%
    Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein.
    Thalidomide-5-OH
  • HY-43722
    Lenalidomide-Br 2093387-36-9 99.86%
    Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein.
    Lenalidomide-Br
  • HY-41547
    Thalidomide 4-fluoride 835616-60-9 99.54%
    Thalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein.
    Thalidomide 4-fluoride
  • HY-131717
    Thalidomide-NH-CH2-COOH 927670-97-1 98.20%
    Thalidomide-NH-CH2-COOH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein.
    Thalidomide-NH-CH2-COOH
  • HY-103597
    Thalidomide-O-COOH 1061605-21-7 99.73%
    Thalidomide-O-COOH (Cereblon ligand 3) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein.
    Thalidomide-O-COOH
  • HY-144841
    CFT7455 2504235-67-8 98.94%
    CFT7455 is an orally active zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3) degrader.
    CFT7455
  • HY-W087383
    Thalidomide 5-fluoride 835616-61-0 99.85%
    Thalidomide 5-fluoride is Thalidomide-based cereblon ligand that incorporates to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
    Thalidomide 5-fluoride
  • HY-A0003B
    Lenalidomide hemihydrate 847871-99-2 99.67%
    Lenalidomide hemihydrate (CC-5013 hemihydrate), a derivative of Thalidomide, acts as molecular glue.
    Lenalidomide hemihydrate
  • HY-126457
    Thalidomide-propargyl 2098487-39-7 99.97%
    Thalidomide-propargyl is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein.
    Thalidomide-propargyl
  • HY-W093272
    Thalidomide-5,6-F 1496997-41-1
    Thalidomide-5,6-F is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein.
    Thalidomide-5,6-F
  • HY-146237
    Golcadomide 2379572-34-4
    Golcadomide (CC-99282) is a potent and orally active cereblon (CRBN) E3 ligase modulator (CELMoD).
    Golcadomide
  • HY-130952
    Thalidomide-O-C8-COOH 2225148-51-4
    Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein.
    Thalidomide-O-C8-COOH
  • HY-103596
    Thalidomide-4-OH 5054-59-1 99.88%
    Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein.
    Thalidomide-4-OH
  • HY-133144
    Lenalidomide-OH 1416990-08-3 99.48%
    Lenalidomide-OH is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein.
    Lenalidomide-OH
  • HY-131385
    KB02-COOH 2375196-30-6 98.88%
    KB02-COOH is a fragment of synthesis of ubiquitin E3 ligase ligand KB02.
    KB02-COOH
  • HY-138040
    CRBN modulator-1 2407829-65-4 98.06%
    CRBN modulator-1, a Thalidomide analog and a CRBN modulator extracted from WO2020006262A1, compound 10, has an IC50 of 3.5 μM and a Ki of 0.98 μM.
    CRBN modulator-1
  • HY-131159
    Thalidomide-O-C8-Boc 2225148-52-5
    Thalidomide-O-C8-Boc is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein.
    Thalidomide-O-C8-Boc