Thalidomide-cyanine 5
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- Formule: C52H60N6O13S2
- Masse moléculaire:1041.20
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
[2]|
Cereblon-DDB1 121.6 nM (Kd) |
In Vitro
Thalidomide-cyanine 5 binds to purified human DDB1-human CRBN protein complex with a Kd of 121.6 nM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 1041.20
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Formule C52H60N6O13S2
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SMILES
O=C1N(C(C2=CC=CC(OCC(NCCCCNC(CCCCCN(/C3=C/C=C/C=C/C4=[N+](C5=C(C4(C)C)C=C(C=C5)S(=O)([O-])=O)CC)C6=C(C3(C)C)C=C(S(=O)(O)=O)C=C6)=O)=O)=C21)=O)C7CCC(NC7=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Mercer JAM, et al. Continuous evolution of compact protein degradation tags regulated by selective molecular glues. Science. 2024;383(6688):eadk4422. [Content Brief]
[2]. Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014;512(7512):49-53. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thalidomide-cyanine 5 Related Classifications
HY-D3392 Related Classifications
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