Signaling Pathway

PI4K

PI4K

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PI4K Inhibitors & Modulators (4)

Product Name Catalog No. Brief Description
PI4KIII beta inhibitor 3

HY-15679

PI4KIII beta inhibitor 3 is a novel and high effective PI4KIII beta inhibitor with IC50 of 5.7 nM.

PI4KIIIbeta-IN-10

HY-100198

PI4KIIIbeta-IN-10 is the most potent PI4KIIIβ inhibitor currently reported, with very minor off-target inhibition of PI4KIIIβ related lipid kinases (IC50 = 3.6 nM).

PI4KIIIbeta-IN-9

HY-19798

PI4KIIIβ-IN-9 is a potent PI4KIIIβ inhibitor (IC50 of 7 nM) and is >140-fold selective over PI3Kγ and >20-fold selective over PI3Kδ, and shows no inhibition of vps34 at concentrations up to 20 μM.

PIK-93

HY-12046

PIK-93 is the first potent, synthetic PI4K (PI4KIIIβ) inhibitor with IC50 of 19 nM; shown to inhibit PI3Kα with IC50 of 39 nM.