1. PI3K/Akt/mTOR
    Anti-infection
  2. PI4K
    HCV
  3. GSK-A1

GSK-A1 

Cat. No.: HY-125118
Handling Instructions

GSK-A1 is a selective type III phosphatidylinositol 4-kinase PI4KA (PI4KIIIα) inhibitor with a pIC50 of 8.5-9.8. GSK-A1 inhibits PtdIns(4,5)P2 resynthesis with an IC50 of about 3 nM. GSK-A1 potently decreases the levels of PtdIns(4)P with a negligible effect on PtdIns(4,5)P2. GSK-A1 has the potential for anti-hepatitis C virus (HCV) research.

For research use only. We do not sell to patients.

GSK-A1 Chemical Structure

GSK-A1 Chemical Structure

CAS No. : 1416334-69-4

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Description

GSK-A1 is a selective type III phosphatidylinositol 4-kinase PI4KA (PI4KIIIα) inhibitor with a pIC50 of 8.5-9.8. GSK-A1 inhibits PtdIns(4,5)P2 resynthesis with an IC50 of about 3 nM. GSK-A1 potently decreases the levels of PtdIns(4)P with a negligible effect on PtdIns(4,5)P2. GSK-A1 has the potential for anti-hepatitis C virus (HCV) research[1].

IC50 & Target[1]

PI4KA

8.5-9.8 (pIC50)

PI4KB

7.2-7.7 (pIC50)

PI4K2A

<5 (pIC50)

PI4K2B

<5 (pIC50)

Molecular Weight

574.63

Formula

C29H27FN6O4S

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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GSK-A1
Cat. No.:
HY-125118
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