Amylases

Amylases are crucial enzymes which hydrolyze internal glycosidic linkages in starch and produce as primary products dextrins and oligosaccharides. Amylases are classified into α-amylase, β-amylase, and glucoamylase based on their three-dimensional structures, reaction mechanisms, and amino acid sequences. Amylases have innumerable applications in clinical, medical, and analytical chemistries as well as in food, detergent, textile, brewing, and distilling industries.

Amylases Inhibitors (8)

Amylases Related Products (10):

Cat. No.	Product Name	Effect	Purity

HY-149008

α-Amylase-IN-3	Inhibitor	99.49%
α-Amylase-IN-3 (Compound 4) is a none-competitive type of α-Amylase inhibitor with an IC₅₀ value of 18.04 μM, which also has radical scavenging activities (DPPH and ABTS) with IC₅₀ values of 16.04 μM (DPPH) and 16.99 μM (ABTS), respectively. α-Amylase-IN-3 has good protein–ligand interactions profile against α-Amylase. α-Amylase-IN-3 may have pharmacological activities such as anti-oxidative, anti-inflammatory inhibitory, which is helpful for the development of diabetes and oxidative stress associated disease.

HY-112835

Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside
Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside (pNP-G7) is the substrate of α-amylase. Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside can be used to measure a-amylase activity.

HY-155961

Antidiabetic agent 2	Inhibitor
Antidiabetic agent 2 (Compound 56) is a glucose-uptake promoter. Antidiabetic agent 2 inhibits DPP-4, PTP-1B, α-amylase, and α-glucosidase with IC₅₀s of 0.036, 0.042, 0.241, 0.185 μM. Antidiabetic agent 2 decreases blood glucose levels.

HY-P2968

Bacterial α-Amylase
Bacterial α-Amylase catalyses the hydrolysis of internal α-1,4-glycosidic linkages in starch in low molecular weight products, such glucose, maltose and maltotriose units. Bacterial α-Amylase is often used in biochemical studies.

HY-N9916

8,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside	Inhibitor
8,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside (Compound 3) is natural product that can be isolated from Bidens bipinnata. 8,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside shows 22% inhibition against α-amylase at 0.556 mg/mL.

HY-149313

α‑Amylase-IN-1	Inhibitor
α Amylase-IN-1 (Compound 11) is an α-Amylase inhibitor with an IC₅₀ value of 0.5509 μM. α Amylase-IN-1 has antioxidant activity with an IC₅₀ value of 53.49 μM for scavenging DPPH free radicals. IC₅₀ can be used in the study of diabetes and oxidative stress-related diseases.

HY-143269

HPA-IN-2	Inhibitor
HPA-IN-2 (Compound 2a-1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC₅₀ values of 8.2 μM and 450.7 μM against HPA and α-glucosidase, respectively.

HY-143268

HPA-IN-1	Inhibitor
HPA-IN-1 (Compound 1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC₅₀ values of 12.0 μM and 410.4 μM against HPA and α-glucosidase, respectively.

HY-N11844

Quercetin 3-(6″-caffeoylsophoroside)	Inhibitor
Quercetin 3-(6″-caffeoylsophoroside) is an orally active α-amylase inhibitor, with an IC₅₀ of 73.66 μg/mL. Quercetin 3-(6″-caffeoylsophoroside) presents in thehydro-methanolic extract of Cardamine hirsuta Linn. Quercetin 3-(6″-caffeoylsophoroside) shows the antidiabetic activities by oxidative stress reduction and α-amylase inhibition. Quercetin 3-(6″-caffeoylsophoroside) can be used for diabetes mellitus research.

HY-154972

α-Amylase/α-Glucosidase-IN-3	Inhibitor
α-Amylase/α-Glucosidase-IN-3 (Compound 17) is an α-Amylase/α-Glucosidase dual inhibitor, with IC₅₀s of 0.70 μM and 1.10 μM. α-Amylase/α-Glucosidase-IN-3 can be used for research of type-II diabetes mellitus.

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