2. Oligonucleotides
  3. Cholesterol

Cholesterol

Cholesterol is a sterol, a type of lipid. Cholesterol is biosynthesized by all animal cells and is an essential structural component of animal cell membranes. Cholesterol is a membrane constituent widely found in biological systems and serves the unique purpose of modulating membrane fluidity, elasticity, as well as permeability. The addition of cholesterol to liposome bilayers prevents a lipid exchange and has an additional stabilizing effect.

Cholesterol (8):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0322
    Cholesterol 57-88-5 98.53%
    Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.
    Cholesterol
  • HY-N0322A
    Cholesterol (Water Soluble)
    Cholesterol Water Soluble can be used for the research of the effects of cholesterol on the potassium currents in inner hair cells (IHCs). Cholesterol is an integral component of the cell membrane and regulates the activity of ion channels in the lipid bilayer.
    Cholesterol (Water Soluble)
  • HY-113217
    Cholesteryl oleate 303-43-5 ≥98.0%
    Cholesteryl oleate is an esterified form of Cholesterol. Cholesteryl oleate can be used in the generation of solid lipid nanoparticle (SLN, a nanoparticle-based method for gene therapy).
    Cholesteryl oleate
  • HY-137131
    DC-Chol hydrochloride 166023-21-8 ≥98.0%
    DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner.
    DC-Chol hydrochloride
  • HY-W127350
    Cholesterol Pelargonate 1182-66-7
    Cholesterol Pelargonate, a Cholesterol derivative, can be used as a triggered release liposome tested.
    Cholesterol Pelargonate
  • HY-W440715
    Cholesterol-PEG-Folate (MW 2000)
    Cholesterol-PEG-Folate (MW 2000) is an excipient and can be used for the preparation of folate-conjugated PEG-liposomes.
    Cholesterol-PEG-Folate (MW 2000)
  • HY-144007
    Chol-PEG 27321-96-6
    Chol-PEG is a nonionic surfactant vesicles and can be used for a blood-persistent drug delivery system.
    Chol-PEG
  • HY-W414069
    Thiocholesterol 1249-81-6
    Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be used for plasma membrane research and drug delivery.
    Thiocholesterol