1. Recombinant Proteins
  2. CD Antigens
  3. Signal Transduction-related CD Proteins

Signal Transduction-related CD Proteins

The cluster of differentiation (CD) antigens is a protocol used for the identification and investigation of cell surface molecules present on leukocytes. Some CD proteins often act as cell-cell or cell-matrix adhesion molecules, cytokine receptors, ion pores, or nutrient transporters. Some CD proteins play a role in cell signaling, other CD molecules mediate cell adhesion. Signal transduction or cell signaling concerns all biochemical processes by which cells translate extracellular signals originating from their environment into specific responses. MCE offers a variety of recombination CD antigens related to cell signal transduction.

Cat. No. Product Name / Synonyms Species Source
  • HY-P73506
    CD84/SLAMF5 Protein, Mouse (221a.a, HEK293, His)

    CD84; SLAM family member 5; SLAMF5

    Mouse HEK293
    CD84/SLAMF5, a self-ligand receptor of the SLAM family, modulates immune cell activation and differentiation through homo- or heterotypic interactions. Its activities are influenced by SH2D1A/SAP and SH2D1B/EAT-2. CD84/SLAMF5 plays roles in NK cell cytotoxicity, T-cell proliferation, interferon gamma secretion, platelet stimulation, hematopoietic progenitor cell marking, and germinal center functions. It contributes to B cell tolerance, prevents autoimmunity, regulates mast cell signaling, and enhances macrophage responses. The protein forms homodimers and interacts with various signaling molecules. CD84/SLAMF5 Protein, Mouse (221a.a, HEK293, His) is the recombinant mouse-derived CD84/SLAMF5 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of CD84/SLAMF5 Protein, Mouse (221a.a, HEK293, His) is 200 a.a., with molecular weight of 37-42 kDa.
  • HY-P73506A
    CD84/SLAMF5 Protein, Mouse (221a.a, HEK293, C-His)

    CD84; SLAM family member 5; SLAMF5

    Mouse HEK293
    CD84/SLAMF5, a self-ligand receptor of the SLAM family, modulates immune cell activation and differentiation through homo- or heterotypic interactions. Its activities are influenced by SH2D1A/SAP and SH2D1B/EAT-2. CD84/SLAMF5 plays roles in NK cell cytotoxicity, T-cell proliferation, interferon gamma secretion, platelet stimulation, hematopoietic progenitor cell marking, and germinal center functions. It contributes to B cell tolerance, prevents autoimmunity, regulates mast cell signaling, and enhances macrophage responses. The protein forms homodimers and interacts with various signaling molecules. CD84/SLAMF5 Protein, Mouse (221a.a, HEK293, C-His) is the recombinant mouse-derived CD84/SLAMF5 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of CD84/SLAMF5 Protein, Mouse (221a.a, HEK293, C-His) is 200 a.a., with molecular weight of 32-37 kDa.
  • HY-P72465
    CD229/SLAMF3 Protein, Human (HEK293, His)

    CD229; cell-surface molecule Ly-9; hly9; Ly9; SLAMF3; T-lymphocyte surface antigen Ly-9

    Human HEK293
    The CD229/SLAMF3 protein is an autoligand receptor in the SLAM family that regulates immune cell activation and differentiation through cell interactions. Essential for innate and adaptive immune responses, its activity is controlled by SH2D1A/SAP and/or SH2D1B/EAT-2. CD229/SLAMF3 Protein, Human (HEK293, His) is the recombinant human-derived CD229/SLAMF3 protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P72705
    CD82 Protein, Human (HEK293, Fc)

    CD82 antigen; C33 antigen; Tspan-27; CD82; KAI1; SAR2; ST6; TSPAN27

    Human HEK293
    CD82, a vital immune response participant, engages with CD4 or CD8 to provide crucial costimulatory signals in the TCR/CD3 pathway. Its direct interaction with IGSF8 plays a pivotal role in modulating immune functions and mediating cellular responses. CD82 Protein, Human (HEK293, Fc) is the recombinant human-derived CD82 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD82 Protein, Human (HEK293, Fc) is 123 a.a., with molecular weight of 40-60 kDa.
  • HY-P72931
    CD74 Protein, Human (HEK293, His)

    HLA class II histocompatibility antigen gamma chain; CD74; CLIP; DHLAG

    Human HEK293
    CD74 is a key component of the class II major histocompatibility complex and serves as a key chaperone in antigen presentation in the regulation of immune responses. It doubles as a cell surface receptor for macrophage migration inhibitory factor (MIF), initiating survival pathways and cell proliferation. CD74 Protein, Human (HEK293, His) is the recombinant human-derived CD74 protein, expressed by HEK293 , with N-His labeled tag. The total length of CD74 Protein, Human (HEK293, His) is 160 a.a., with molecular weight of 30-40 kDa.
  • HY-P72710
    CD74 Protein, Mouse (160a.a, HEK293, His)

    H-2 class II histocompatibility antigen gamma chain; CD74; CLIP; DHLAG

    Mouse HEK293
    The CD74 protein is significantly expressed in the thymus and lymph nodes, suggesting that it plays a key role in regulating immune system function. Its presence in the thymus, a key site for T cell development, underscores its important role in overseeing key cellular processes required for immune maturation. CD74 Protein, Mouse (160a.a, HEK293, His) is the recombinant mouse-derived CD74 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD74 Protein, Mouse (160a.a, HEK293, His) is 160 a.a., with molecular weight of 25-30 kDa.
  • HY-P77326
    CD84/SLAMF5 Protein, Cynomolgus/Rhesus Macaque (HEK293, His)

    SLAM family member 5; CD84; Ly-9B; SLAMF5

    Rhesus Macaque HEK293
    CD84/SLAMF5 protein is a self-ligand receptor in the SLAM family that regulates the activities of various immune cells through homotypic or heterotypic cell-cell interactions. It fine-tunes its function based on the presence or absence of small cytoplasmic adapter proteins, including SH2D1A/SAP and/or SH2D1B/EAT-2. CD84/SLAMF5 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived CD84/SLAMF5 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD84/SLAMF5 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is 220 a.a., with molecular weight of 35-50 KDa.
  • HY-P78262
    CD74 Protein, Mouse (224a.a, HEK293, His)

    CD74; Ii; DHLAG; HLADG; Ia-GAMMA; p33; CLIP; INVG34; Ia-GAMMA ; II

    Mouse HEK293
    The CD74 protein is significantly expressed in the thymus and lymph nodes, suggesting that it plays a key role in regulating immune system function. Its presence in the thymus, a key site for T cell development, underscores its important role in overseeing key cellular processes required for immune maturation. CD74 Protein, Mouse (224a.a, HEK293, His) is the recombinant mouse-derived CD74 protein, expressed by HEK293 , with N-His labeled tag. The total length of CD74 Protein, Mouse (224a.a, HEK293, His) is 224 a.a., with molecular weight of 40-50 kDa.
  • HY-P76812
    CD82 Protein, Human (HEK293, His)

    CD82 antigen; C33 antigen; Tspan-27; CD82; KAI1; SAR2; ST6; TSPAN27

    Human HEK293
    CD82, a vital immune response participant, engages with CD4 or CD8 to provide crucial costimulatory signals in the TCR/CD3 pathway. Its direct interaction with IGSF8 plays a pivotal role in modulating immune functions and mediating cellular responses. CD82 Protein, Human (HEK293, His) is the recombinant human-derived CD82 protein, expressed by HEK293, with C-His labeled tag. The total length of CD82 Protein, Human (HEK293, His) is 118 a.a., with molecular weight of 25-33 kDa.
  • HY-P78487
    CD229/SLAMF3 Protein, Human (HEK293, His-Avi)

    SLAMF3; CD229; LY9; AI893573; Lgp100; T100

    Human HEK293
    The CD229/SLAMF3 protein is an autoligand receptor in the SLAM family that regulates immune cell activation and differentiation through cell interactions. Essential for innate and adaptive immune responses, its activity is controlled by SH2D1A/SAP and/or SH2D1B/EAT-2. CD229/SLAMF3 Protein, Human (HEK293, His-Avi) is the recombinant human-derived CD229/SLAMF3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of CD229/SLAMF3 Protein, Human (HEK293, His-Avi) is 407 a.a., with molecular weight of 70-80 kDa.
  • HY-P72414
    CD84/SLAMF5 Protein, Human (Biotinylated, HEK293, His-Avi)

    SLAM family member 5; Cell surface antigen MAX.3; Hly9-beta; Signaling lymphocytic activation molecule 5; CD84

    Human HEK293
    The CD84/SLAMF5 protein, a self-ligand receptor in the SLAM family, modulates diverse immune cell activities through homo- or heterotypic cell-cell interactions. It finely tunes its functions based on the presence or absence of small cytoplasmic adapter proteins, including SH2D1A/SAP and/or SH2D1B/EAT-2. CD84/SLAMF5 mediates NK cell cytotoxicity dependent on SH2D1A and SH2D1B, enhances T-cell proliferative responses, and amplifies IFNG secretion. It is crucial for prolonged T-cell:B-cell contact, germinal center formation, and maintaining B-cell tolerance. In mast cells, it negatively regulates immunoglobulin epsilon receptor signaling, and in macrophages, it positively regulates LPS-induced MAPK phosphorylation and NF-kappaB activation. Additionally, CD84/SLAMF5 positively regulates macroautophagy in dendritic cells and forms homodimers, interacting with CD48 molecules and various signaling proteins, including SH2D1A/SAP, SH2D1B/EAT-2, PTPN6/SHP-1, PTPN11/SHP-2, and INPP5D/SHIP1. CD84/SLAMF5 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD84/SLAMF5 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of CD84/SLAMF5 Protein, Human (Biotinylated, HEK293, His-Avi) is 199 a.a., with molecular weight of 40-50 kDa.
  • HY-P72463
    CD84/SLAMF5 Protein, Human (199a.a, HEK293, His)

    SLAM family member 5; CD84; Ly-9B; SLAMF5

    Human HEK293
    CD84/SLAMF5 protein is a self-ligand receptor in the SLAM family that regulates the activities of various immune cells through homotypic or heterotypic cell-cell interactions. It fine-tunes its function based on the presence or absence of small cytoplasmic adapter proteins, including SH2D1A/SAP and/or SH2D1B/EAT-2. CD84/SLAMF5 Protein, Human (199a.a, HEK293, His) is the recombinant human-derived CD84/SLAMF5 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD84/SLAMF5 Protein, Human (199a.a, HEK293, His) is 199 a.a., with molecular weight of 35-43 kDa.
  • HY-P72464
    CD229/SLAMF3 Protein, Mouse (407a.a, HEK293, His)

    CD229; cell-surface molecule Ly-9; hly9; Ly9; SLAMF3; T-lymphocyte surface antigen Ly-9

    Mouse HEK293
    The CD229/SLAMF3 protein is an autoligand receptor in the SLAM family that regulates immune cell activation and differentiation through homotypic or heterotypic interactions. These interactions are mediated by cytoplasmic adapters such as SH2D1A/SAP or SH2D1B/EAT-2 and are critical for coordinating innate and adaptive immune responses. CD229/SLAMF3 Protein, Mouse (407a.a, HEK293, His) is the recombinant mouse-derived CD229/SLAMF3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD229/SLAMF3 Protein, Mouse (407a.a, HEK293, His) is 407 a.a., with molecular weight of 65-75 kDa.
  • HY-P75396
    CD53 Protein, Mouse (HEK293, His)

    Leukocyte surface antigen CD53; Cell surface glycoprotein CD53; CD53

    Mouse HEK293
    CD53 Protein plays a crucial role in efficient myofiber formation during muscle regeneration, specifically facilitating cell fusion. Additionally, CD53 is implicated in growth regulation in hematopoietic cells. Its interaction with SCIMP underscores its involvement in various cellular processes. CD53 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD53 protein, expressed by HEK293 , with N-His labeled tag. The total length of CD53 Protein, Mouse (HEK293, His) is 75 a.a., with molecular weight of ~22 kDa.
  • HY-P76806
    CD53 Protein, Cynomolgus (HEK293, His)

    Leukocyte surface antigen CD53; Cell surface glycoprotein CD53

    Cynomolgus HEK293
    The CD53 Protein, a vital tetraspanin family member, plays an essential role in immune responses, cell adhesion, and signal transduction. Its study enhances understanding of cell membrane organization and function, with potential applications in immunology and cancer research. Classification within the tetraspanin family emphasizes unique contributions to diverse physiological processes. Further exploration promises insights into CD53's role in both normal physiology and pathological conditions. CD53 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD53 protein, expressed by HEK293, with N-His labeled tag. The total length of CD53 Protein, Cynomolgus (HEK293, His) is 75 a.a., with molecular weight of 19-22 kDa.
  • HY-P76807
    CD53 Protein, Cynomolgus (HEK293, Fc)

    Leukocyte surface antigen CD53; Cell surface glycoprotein CD53

    Cynomolgus HEK293
    The CD53 Protein, a vital tetraspanin family member, plays an essential role in immune responses, cell adhesion, and signal transduction. Its study enhances understanding of cell membrane organization and function, with potential applications in immunology and cancer research. Classification within the tetraspanin family emphasizes unique contributions to diverse physiological processes. Further exploration promises insights into CD53's role in both normal physiology and pathological conditions. CD53 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived CD53 protein, expressed by HEK293, with N-mFc labeled tag. The total length of CD53 Protein, Cynomolgus (HEK293, Fc) is 75 a.a., with molecular weight of ~44 kDa.
  • HY-P77325
    CD84/SLAMF5 Protein, Cynomolgus (HEK293, Fc)

    SLAM family member 5; CD84; Ly-9B; SLAMF5

    Cynomolgus HEK293
    CD84/SLAMF5 protein is a self-ligand receptor in the SLAM family that regulates the activities of various immune cells through homotypic or heterotypic cell-cell interactions. It fine-tunes its function based on the presence or absence of small cytoplasmic adapter proteins, including SH2D1A/SAP and/or SH2D1B/EAT-2. CD84/SLAMF5 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived CD84/SLAMF5 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD84/SLAMF5 Protein, Cynomolgus (HEK293, Fc) is 220 a.a., with molecular weight of ~57 & 65 kDa, respectively.
  • HY-P78418
    CD84/SLAMF5 Protein, Human (HEK293, His-Avi)

    Hly9-beta; CD84; SLAMF5; LY9B; CD84 molecule; DKFZp781E2378; Hly9-β

    Human HEK293
    CD84/SLAMF5 protein is a self-ligand receptor in the SLAM family that regulates the activities of various immune cells through homotypic or heterotypic cell-cell interactions. It fine-tunes its function based on the presence or absence of small cytoplasmic adapter proteins, including SH2D1A/SAP and/or SH2D1B/EAT-2. CD84/SLAMF5 Protein, Human (HEK293, His-Avi) is the recombinant human-derived CD84/SLAMF5 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of CD84/SLAMF5 Protein, Human (HEK293, His-Avi) is 204 a.a., with molecular weight of 40-55 kDa.
  • HY-P700672
    CD229/SLAMF3 Protein, Human (Biotinylated, HEK293, His-Avi)

    SLAMF3; CD229; LY9; AI893573; Lgp100; T100

    Human HEK293
    CD229/SLAMF3 Protein, a self-ligand receptor in the SLAM family, modulates immune cell activation and differentiation through cell interactions. Crucial for innate and adaptive immune responses, its activities are controlled by SH2D1A/SAP and/or SH2D1B/EAT-2. It mediates T-cell adhesion, promotes Th17 differentiation with IL-17 secretion requiring SH2D1A, and facilitates RORC recruitment to the IL-17 promoter. CD229/SLAMF3 acts as a negative immune regulator, inhibiting autoantibody responses and CD4(+) T-cell IFN-gamma secretion. It regulates thymic innate CD8(+) T-cell size and iNKT cell development, interacting with SH2D1A, SH2D1B, INPP5D, and PTPN11, blocking PTPN11 interaction with SH2D1A. CD229/SLAMF3 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD229/SLAMF3 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of CD229/SLAMF3 Protein, Human (Biotinylated, HEK293, His-Avi) is 407 a.a., with molecular weight of 70-80 kDa.
Cat. No. Product Name Effect Purity