1. MAPK/ERK Pathway
  2. Mixed Lineage Kinase

Mixed Lineage Kinase

Mixed Lineage Kinase Related Products (2):

Cat. No. Product Name Effect Purity
  • HY-100573
    Necrosulfonamide Inhibitor >98.0%
    Necrosulfonamide is a pharmacological inhibitor of MLKL with IC50 values of 124 nM in human HT-29.
  • HY-12599
    URMC-099 Inhibitor 99.82%
    URMC-099 is an orally bioavailable, brain penetrant inhibitor of Mixed Lineage Kinase 3(MLK3) with IC50 of 14 nM; inhibits LPS-induced TNFα release in microglial cells, HIV-1 Tat-induced release of cytokines in human monocytes, and up-regulation of phospho-JNK in Tat-injected brains of mice.