Signaling Pathway

Histone Acetyltransferase

Histone Acetyltransferase

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Histone Acetyltransferase Inhibitors & Modulators (4)

Product Name Catalog No. Brief Description


C646 is a selective competitive histone acetyltransferase p300 inhibitor with Ki of 400 nM; less potent for other acetyltransferases.

Histone Acetyltransferase Inhibitor II


Histone Acetyltransferase Inhibitor II, insulin producing cells capable of secreting blood glucose regulating hormones, specially insulin, in response to physiological signals, method of production of said cells and uses thereof.



I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor, that targets the CBP/p300 bromodomains.

MG 149


MG149 is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM); little potent for PCAF and p300(IC50 >200 uM).