1197996-80-7

CBL0137 Chemical Structure
1197996-80-7

Chemical Structure

CBL0137

Synonym(s): Curaxin 137; CBL-C137

  • CAS No.: 1197996-80-7
  • Formula:C21H24N2O2
  • Molecular Weight:336.43

IUPAC Name: 1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one)

InChIKey: JKCSODVERGVDLT-UHFFFAOYSA-N

SMILES: CC(NCCN1C2=C(C3=C1C=CC(C(C)=O)=C3)C=C(C(C)=O)C=C2)C

Biological Activity: CBL0137, a curaxin compound, is a histone chaperone facilitates chromatin transcription (FACT) inhibitor. CBL0137 downregulates NF-κB and activates p53. CBL0137 restores both histone H3 acetylation and trimethylation. CBL0137 is an anticancer agent. CBL0137 induces cancer cell apoptosis[1].

Cat. No. Product Name Purity Description Pricing
HY-18935
CBL0137 99.73% CBL0137, a curaxin compound, is a histone chaperone facilitates chromatin transcription (FACT) inhibitor. CBL0137 downregulates NF-κB and activates p53. CBL0137 restores both histone H3 acetylation and trimethylation. CBL0137 is an anticancer agent. CBL0137 induces cancer cell apoptosis.
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