1. Membrane Transporter/Ion Channel
  2. Calcium Channel

Calcium Channel

Calcium channel is an ion channel which displays selective permeability to calcium ions. It is sometimes synonymous as voltage-dependent calcium channel, although there are also ligand-gated calcium channels. Voltage-gated calcium (CaV) channels catalyse rapid, highly selective influx of Ca2+ into cells despite a 70-fold higher extracellular concentration of Na+. Some calcium channel blockers have the added benefit of slowing your heart rate, which can further reduce blood pressure, relieve chest pain (angina) and control an irregular heartbeat.

Calcium Channel Related Products (66):

Cat. No. Product Name Effect Purity
  • HY-A0064
    Verapamil hydrochloride Antagonist 99.97%
    Verapamil hydrochloride is an L-type calcium channel antagonist.
  • HY-B0407A
    Chlorpromazine hydrochloride Inhibitor 99.85%
    Chlorpromazine Hydrochloride is an antagonist of the dopamine D2 receptors, 5-HT2A receptors, potassium channel, sodium channel, with Ki of 363 nM and 8.3 nM for dopamine D2 receptor and serotonin 5-HT2A receptor, respectively.
  • HY-B0470
    Neomycin sulfate Inhibitor >98.0%
    Neomycin sulfate is an aminoglycoside antibiotic and calcium channel inhibitor.
  • HY-B0284
    Nifedipine Antagonist 99.56%
    Nifedipine is a potent calcium channel blocker and drug of choice for cardiac insufficiencies.
  • HY-15553A
    Mibefradil dihydrochloride Inhibitor >98.0%
    Mibefradil dihydrochloride is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively.
  • HY-101096
    MK-8998 Antagonist 99.82%
    MK-8998 is a potent and selective antagonist of the T-type calcium channel.
  • HY-14656
    Diltiazem hydrochloride Antagonist 98.39%
    Diltiazem hydrochloride is a Ca2+ influx inhibitor (slow channel blocker or calcium antagonist).
  • HY-15124
    Bay-K-8644 (S)-(-)- Activator 98.34%
    Bay-K-8644 ((S)-(-)-) is a Ca2+ channel activator; L-type Ca2+ channel activator.
  • HY-B0282
    Acetylcholine chloride Activator >98.0%
    Acetylcholine is a neurotransmitter that can induce the opening of calcium channels.
  • HY-15125
    Bay-K-8644 (R)-(+)- Activator
    Bay-K-8644 ((R)-(+)-) is a Ca2+ channel activator; L-type Ca2+ channel activator.
  • HY-17404
    Cilnidipine Inhibitor 99.92%
    Cilnidipine(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity.
  • HY-12515A
    Nicardipine Hydrochloride Inhibitor >98.0%
    Nicardipine Hcl(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage.
  • HY-B0265
    Nimodipine Inhibitor 99.58%
    Nimodipine(Nimotop) is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy.
  • HY-12542A
    Dantrolene sodium hemiheptahydrate Inhibitor >98.0%
    Dantrolene sodium hemiheptahydrate is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction.
  • HY-B0317
    Amlodipine Antagonist 99.52%
    Amlodipine is a long-acting calcium channel blocker.
  • HY-B0106
    Levetiracetam Inhibitor
    Levetiracetam(UCB L059) is a novel anticonvulsant with antihyperalgesic efficacy in inflammatory pain.
  • HY-B0317B
    Amlodipine besylate Antagonist 98.16%
    Amlodipine besylate is a long-acting calcium channel blocker.
  • HY-B0320A
    Cromolyn sodium Inhibitor 99.86%
    Cromolyn sodium is an antiallergic drug.
  • HY-17401
    Ranolazine dihydrochloride Inhibitor 99.86%
    Ranolazine(RS-43285) is an antianginal agent with antiarrhythmic properties that achieves its effects via a novel mechanism of action (inhibition of the late phase of the inward sodium current), without affecting heart rate or blood pressure (BP).
  • HY-B0358A
    Flunarizine dihydrochloride Inhibitor 99.85%
    Flunarizine is a selective calcium entry blocker.