1. Membrane Transporter/Ion Channel
  2. Calcium Channel

Calcium Channel

Calcium channel is an ion channel which displays selective permeability to calcium ions. It is sometimes synonymous as voltage-dependent calcium channel, although there are also ligand-gated calcium channels. Voltage-gated calcium (CaV) channels catalyse rapid, highly selective influx of Ca2+ into cells despite a 70-fold higher extracellular concentration of Na+. Some calcium channel blockers have the added benefit of slowing your heart rate, which can further reduce blood pressure, relieve chest pain (angina) and control an irregular heartbeat.

Calcium Channel Related Products (111):

Cat. No. Product Name Effect Purity
  • HY-A0064
    Verapamil hydrochloride Antagonist 99.95%
    Verapamil hydrochloride is a calcium channel antagonist.
  • HY-B0470
    Neomycin sulfate Inhibitor >98.0%
    Neomycin sulfate is an aminoglycoside antibiotic used for preventing or treating bacterial infections.
  • HY-B0284
    Nifedipine Antagonist
    Nifedipine (BAY-a-1040) is a potent calcium channel blocker and drug of choice for cardiac insufficiencies.
  • HY-B0282
    Acetylcholine chloride Activator >98.0%
    Acetylcholine (chloride) is a common neurotransmitter found in the central and peripheral nerve system.
  • HY-13434
    Ionomycin >98.0%
    Ionomycin (SQ23377) is a Calcium ionophore and an antibiotic produced by Streptomyces conglobatus ATCC 31005.
  • HY-13433
    Thapsigargin Inhibitor >99.0%
    Thapsigargin is an inhibitor of microsomal Ca2+-ATPase.
  • HY-Z0816
    Dehydronitrosonisoldipine Antagonist 98.79%
    Dehydronitrosonisoldipine is a calcium channel antagonist.
  • HY-B1671
    (+)-Kavain 99.98%
    (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels. (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied.
  • HY-15124
    Bay-K-8644 ((S)-(-)-) Agonist 98.34%
    Bay-K-8644 (S)-(-)- is an agonist of L-type Ca2+ channel. Bay-K-8644 (S)-(-)- activates Ba2+ currents (IBa) (EC50=32 nM).
  • HY-B0265
    Nimodipine Inhibitor 99.87%
    Nimodipine(Nimotop) is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.
  • HY-15553A
    Mibefradil dihydrochloride Inhibitor 99.63%
    Mibefradil dihydrochloride is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively.
  • HY-B0106
    Levetiracetam Inhibitor
    Levetiracetam(UCB L059) is a novel anticonvulsant with antihyperalgesic efficacy in inflammatory pain.
  • HY-12542A
    Dantrolene sodium hemiheptahydrate Inhibitor >98.0%
    Dantrolene sodium hemiheptahydrate is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction.
  • HY-101455
    CDN1163 Activator 99.12%
    CDN1163 is a sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) activator.
  • HY-B0320A
    Cromolyn sodium Inhibitor 99.97%
    Cromolyn (sodium) is an antiallergic drug.
  • HY-14656
    Diltiazem hydrochloride Antagonist 98.39%
    Diltiazem hydrochloride is a Ca2+ influx inhibitor (slow channel blocker or calcium antagonist).
  • HY-B1221
    Flufenamic acid Inhibitor 99.92%
    Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels.
  • HY-B0317B
    Amlodipine besylate Antagonist 98.21%
    Amlodipine besylate is a long-acting calcium channel blocker.
  • HY-B0317
    Amlodipine Antagonist 99.57%
    Amlodipine is a long-acting calcium channel blocker.
  • HY-12515A
    Nicardipine Hydrochloride Inhibitor 99.85%
    Nicardipine Hcl(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage.
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