1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Stem Cell/Wnt
    TGF-beta/Smad
  3. ROCK
  4. ROCK1 Inhibitors

ROCK1 Inhibitors

ROCK

ROCK1

ROCK2

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform ROCK1 together.

Please try each isoform separately.

ROCK1 Specific Inhibitors
Product Name ROCK1 ROCK2 ROCK1 Selectivity Purity
Fasudil Hydrochloride
p160ROCK, Ki: 0.33 μM
  Selective Inhibitor 99.91%
GSK180736A
ROCK1, IC50: 100 nM
  Selective Inhibitor 98.05%
Fasudil
p160ROCK, Ki: 0.33 μM
  Selective Inhibitor
Y-27632 dihydrochloride
ROCK-I, Ki: 220 nM
ROCK-II, Ki: 300 nM
Pan Inhibitor 99.83%
Y-27632
ROCK-I, Ki: 220 nM
ROCK-II, Ki: 300 nM
Pan Inhibitor 99.65%
SLx-2119
ROCK1, IC50: 24 μM
ROCK2, IC50: 105 nM
Pan Inhibitor 99.59%
ROCK inhibitor-2
ROCK1, IC50: 17 nM
ROCK2, IC50: 2 nM
Pan Inhibitor
SB-772077B dihydrochloride
ROCK1, IC50: 5.6 nM
ROCK2, IC50: 6 nM
Pan Inhibitor >99.0%
GSK269962A
ROCK1, IC50: 1.6 nM
ROCK2, IC50: 4 nM
Pan Inhibitor 98.01%
RKI-1447
ROCK1, IC50: 14.5 nM
ROCK2, IC50: 6.2 nM
Pan Inhibitor 97.26%
Azaindole 1
ROCK-1, IC50: 0.6 nM
ROCK-2, IC50: 1.1 nM
Pan Inhibitor 99.46%
Ripasudil
ROCK1, IC50: 51 nM
ROCK2, IC50: 19 nM
Pan Inhibitor 99.75%
SR-3677
ROCK-I, IC50: 56 nM
ROCK-II, IC50: 3 nM
Pan Inhibitor 99.46%
AT13148
ROCKI, IC50: 6 nM
ROCKII, IC50: 4 nM
Pan Inhibitor 99.54%
Hydroxyfasudil
ROCK1, IC50: 0.73 μM
ROCK2, IC50: 0.72 μM
Pan Inhibitor 98.13%
BDP5290
ROCK1, IC50: 5 nM
ROCK2, IC50: 50 nM
Pan Inhibitor >98.0%
SAR407899
ROCK-1, IC50: 276 nM
ROCK-2, IC50: 102 nM
Pan Inhibitor 98.43%
Hydroxyfasudil hydrochloride
ROCK1, IC50: 0.73 μM
ROCK2, IC50: 0.72 μM
Pan Inhibitor 99.40%
SAR407899 hydrochloride
ROCK-1, IC50: 276 nM
ROCK-2, IC50: 102 nM
Pan Inhibitor 99.81%
Ripasudil free base
ROCK1, IC50: 51 nM
ROCK2, IC50: 19 nM
Pan Inhibitor