867017-68-3
867017-68-3
Chemical Structure
BAY-549
Synonym(s): ROCK-IN-2; Azaindole 1; TC-S 7001
- CAS No.: 867017-68-3
- Formula:C18H13ClF2N6O
- Molecular Weight:402.79
IUPAC Name: 6-chloro-N4-(3,5-difluoro-4-((3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)pyrimidine-2,4-diamine
InChIKey: NRSGWEVTVGZDFC-UHFFFAOYSA-N
SMILES: NC1=NC(Cl)=CC(NC2=CC(F)=C(OC3=C4C(NC=C4C)=NC=C3)C(F)=C2)=N1
Biological Activity: BAY-549 (Azaindole 1), a chemical probe, is an orally active and ATP-competitive ROCK inhibitor with IC50s of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BAY-549 | 98.16% | BAY-549 (Azaindole 1), a chemical probe, is an orally active and ATP-competitive ROCK inhibitor with IC50s of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2, respectively. | ||||||||||||||||||||
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BAY-549 (Standard) | ≥98% | BAY-549 (Standard) is the analytical standard of BAY-549 (HY-10319). This product is intended for research and analytical applications. BAY-549 (Azaindole 1), a chemical probe, is an orally active and ATP-competitive ROCK inhibitor with IC50s of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2, respectively. | ||||||||||||||||||||
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