HGF & Receptors
Hepatocyte growth factor (HGF, also known as Scatter Factor) is among a group of factors possessing angiogenic ability. It belongs to the soluble cytokine family and is also a member of the plasminogen-related growth factor family. HGF is secreted by mesenchymal stem cells，and regulates cell growth, cell motility and morphogenesis of epithelial cells, endothelial cells, and haematopoietic stem cells, through its receptor, c-Met. Under normal conditions, HGF/c-Met axis plays an important role in normal biological functions in organism. However, in cancer cells, abnormal activation of HGF/c-Met axis promotes tumor development and progression by stimulating the PI3K/AKT, Ras/MAPK, JAK/STAT, SRC, Wnt/β-catenin, and other signaling pathways.
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HGF & Receptors Recombinant Proteins (59)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
