1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. HGF & Receptors

Hepatocyte growth factor (HGF, also known as Scatter Factor) is among a group of factors possessing angiogenic ability. It belongs to the soluble cytokine family and is also a member of the plasminogen-related growth factor family. HGF is secreted by mesenchymal stem cells,and regulates cell growth, cell motility and morphogenesis of epithelial cells, endothelial cells, and haematopoietic stem cells, through its receptor, c-Met. Under normal conditions, HGF/c-Met axis plays an important role in normal biological functions in organism. However, in cancer cells, abnormal activation of HGF/c-Met axis promotes tumor development and progression by stimulating the PI3K/AKT, Ras/MAPK, JAK/STAT, SRC, Wnt/β-catenin, and other signaling pathways.

Cat. No. Product Name / Synonyms Species Source
  • HY-P7121
    HGF Protein, Human (CHO)

    rHuHGF; Hepatopoietin-A; SF

    Human CHO
    HGF Protein, Human (CHO) is a cytokine binding to Met tyrosine kinase receptor, and exhibits biological activities.
  • HY-P73928
    HGF Protein, Mouse (HEK293)

    Hepatocyte growth factor; F-TCF; Hepatopoeitin-A; HGF; HGFB; HPTA; SF

    Mouse HEK293
    HGF Protein, a potent mitogen, stimulates mature hepatocyte cell growth and acts as a hepatotrophic factor for various tissues. As an activating ligand for MET receptor tyrosine kinase, HGF binds and promotes dimerization, activating MAPK signaling through TMPRSS13 cleavage. Structurally, HGF comprises alpha and beta chains connected by a disulfide bond. Interaction with SRPX2 enhances its mitogenic activity. HGF Protein, Mouse (HEK293) is the recombinant mouse-derived HGF protein, expressed by HEK293 , with tag free. The total length of HGF Protein, Mouse (HEK293) is 696 a.a., with molecular weight of ~93 kDa.
  • HY-P70627
    HGF Protein, Human (HEK293, His)

    Hepatocyte growth factor; HPTA; HGF; SF; Scatter factor; Hepatopoietin-A

    Human HEK293
    HGF Protein is a hepatocyte growth factor involved in signaling pathways including MET and MAPK. The HGF Protein consists of 728 amino acids, with an alpha chain containing an n-terminal domain four kringle domains, and a β serine protease domain. HGF Protein, Human (HEK293, His) is the recombinant human-derived HGF protein, expressed by HEK293 , with C-His labeled tag. The total length of HGF Protein, Human (HEK293, His) is 697 a.a., with molecular weight of 32-37 & 52-70 & 80-100 kDa, respectively.
  • HY-P72267
    HGFR Protein, Human (HEK293, hFc)

    HGF receptor; SF receptor; Tyrosine-protein kinase Met

    Human HEK293
    The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. HGFR Protein, Human (HEK293, hFc) is the recombinant human-derived HGFR protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P72938
    HGFR Protein, Human (sf9, His-GST)

    Hepatocyte growth factor receptor; HGF receptor; SF receptor; MET

    Human Sf9 insect cells
    The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. HGFR Protein, Human (sf9, His-GST) is the recombinant human-derived HGFR protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
  • HY-P78490
    HGFR Protein, Human (HEK293, His-Avi)

    MET; oncogene MET; HGF R; HGF/SF receptor; AUTS9; cMET; Met (c-Met); RCCP2; SF receptor

    Human HEK293
    The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. HGFR Protein, Human (HEK293, His-Avi) is the recombinant human-derived HGFR protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
  • HY-P72934
    HGFR Protein, Canine (HEK293, His)

    Hepatocyte growth factor receptor; HGF receptor; SF receptor; MET

    Canine HEK293
    The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF. It regulates proliferation, scattering, morphogenesis, and cell survival. HGFR Protein, Canine (HEK293, His) is the recombinant canine-derived HGFR protein, expressed by HEK293 , with N-His labeled tag. The total length of HGFR Protein, Canine (HEK293, His) is 911 a.a., with molecular weight of ~35-43 kDa & 80-100 kDa, respectively.
  • HY-P72941
    HGFR Protein, Mouse (HEK293, His)

    Hepatocyte growth factor receptor; HGF receptor; SF receptor; MET

    Mouse HEK293
    HGFR Protein, a receptor tyrosine kinase, transduces signals by binding hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. Upon ligand binding, HGFR undergoes autophosphorylation, creating docking sites for downstream molecules like PI3K, PLCG1, SRC, GRB2, STAT3, or GAB1, activating RAS-ERK, PI3K-AKT, and PLCgamma-PKC cascades. HGFR Protein, Mouse (HEK293, His) is the recombinant mouse-derived HGFR protein, expressed by HEK293, with C-His labeled tag. The total length of HGFR Protein, Mouse (HEK293, His) is 905 a.a., with molecular weight of ~34-42 kDa & 79-90 kDa, respectively.
  • HY-P70561
    HGF Protein, Mouse (696a.a, HEK293, His)

    Hepatopoietin-A; Scatter factor; SF; deafness, autosomal recessive 39; DFNB39; F-TCF; hepatocyte growth factor; HGF

    Mouse HEK293
    HGF Protein, a potent mitogen, stimulates mature hepatocyte cell growth and acts as a hepatotrophic factor for various tissues. As an activating ligand for MET receptor tyrosine kinase, HGF binds and promotes dimerization, activating MAPK signaling through TMPRSS13 cleavage. Structurally, HGF comprises alpha and beta chains connected by a disulfide bond. Interaction with SRPX2 enhances its mitogenic activity. HGF Protein, Mouse (696a.a, HEK293, His) is the recombinant mouse-derived HGF protein, expressed by HEK293 , with C-6*His labeled tag. The total length of HGF Protein, Mouse (696a.a, HEK293, His) is 696 a.a., with molecular weight of (50-90) & (30-34) kDa, respectively.
  • HY-P73101
    HGF Protein, Rat (HEK293)

    Hepatocyte growth factor; F-TCF; Hepatopoeitin-A; HGF; HGFB; HPTA; SF

    Rat HEK293
    The HGF gene encodes hepatocyte growth factor (HGF), a protein involved in organ regeneration, angiogenesis, and myelination. It is located in the extracellular space and serves as a biomarker for cholangiocarcinoma. Implicated in various diseases, HGF plays a crucial role in physiological and pathological conditions. It shows biased expression in the liver (RPKM 137.5), lung (RPKM 132.1), and other tissues. HGF Protein, Rat (HEK293) is the recombinant rat-derived HGF protein, expressed by HEK293 , with tag free. The total length of HGF Protein, Rat (HEK293) is 696 a.a., with molecular weight of ~92 kDa.
  • HY-P75809
    HGF Protein, Cynomolgus (HEK293)

    Hepatocyte growth factor; F-TCF; Hepatopoeitin-A; HGF; HGFB; HPTA; SF

    Cynomolgus HEK293
    HGF Protein, a potent mitogen, stimulates mature hepatocyte growth and exhibits hepatotrophic properties for various tissues. It acts as an activating ligand for the receptor tyrosine kinase MET, promoting dimerization upon binding. Structurally, HGF Protein comprises alpha and beta chains linked by a disulfide bond. Additionally, it interacts with SRPX2, enhancing HGF's mitogenic activity. HGF Protein, Cynomolgus (HEK293) is the recombinant cynomolgus-derived HGF protein, expressed by HEK293 , with tag free. The total length of HGF Protein, Cynomolgus (HEK293) is 728 a.a., with molecular weight of ~89 & 58 & 34 & 32 kDa, respectively.
  • HY-P70715
    HGFR Protein, Human (HEK293, Fc)

    Hepatocyte growth factor receptor; HGF receptor; HGF/SF receptor; Proto-oncogene c-Met; Scatter factor receptor; SF receptor; Tyrosine-protein kinase Met; MET

    Human HEK293
    The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. HGFR Protein, Human (HEK293, Fc) is the recombinant human-derived HGFR protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P72942
    HGFR Protein, Rat (HEK293, Fc)

    Hepatocyte growth factor receptor; HGF receptor; SF receptor; MET

    Rat HEK293
    HGFR Protein is a receptor tyrosine kinase that acts as a signal transducer of the extracellular matrix by binding to hepatocyte growth factor /HGF ligands. HGFR Protein participate in the activation of RAS-ERK, PI3 kinase-AKT, and PLCgamma-PKC signaling pathways. HGFR Protein is essential for embryonic development, organogenesis, and wound healing. HGFR Protein, Rat (HEK293, Fc) is the recombinant rat-derived HGFR protein, expressed by HEK293, with C-hFc labeled tag. The total length of HGFR Protein, Rat (HEK293, Fc) is 908 a.a., with molecular weight of ~97 & 39 kDa, respectively.
  • HY-P71688
    HGF Protein, Rat (GST)

    Hgf; Hepatocyte growth factor; Hepatopoietin-A

    Rat E. coli
    HGF Protein, a potent mitogen, stimulates mature hepatocyte cell growth, acting as a hepatotrophic factor for various tissues. It activates MAPK signaling through TMPRSS13 cleavage and activates MET receptor tyrosine kinase by promoting its dimerization. Structurally, HGF comprises alpha and beta chains connected by a disulfide bond. Interaction with SRPX2 enhances its mitogenic activity. HGF Protein, Rat (GST) is the recombinant rat-derived HGF protein, expressed by E. coli , with N-GST labeled tag. The total length of HGF Protein, Rat (GST) is 252 a.a., with molecular weight of ~55.0 kDa.
  • HY-P72940
    HGFR Protein, Mouse (HEK293, Fc)

    Hepatocyte growth factor receptor; HGF receptor; SF receptor; MET

    Mouse HEK293
    The HGFR protein is a receptor tyrosine kinase that transduces signals from the extracellular matrix by binding to hepatocyte growth factor/HGF ligand. This interaction regulates proliferation, scattering, morphogenesis, and cell survival. HGFR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived HGFR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of HGFR Protein, Mouse (HEK293, Fc) is 905 a.a., with molecular weight of ~43 kDa.
  • HY-P701263
    FITC-Labeled HGFR Protein, Human (HEK293, His)

    MET; AUTS9; HGFR; RCCP2; c-Met

    Human HEK293
    The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. FITC-Labeled HGFR Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled HGFR protein, expressed by HEK293 , with His labeled tag. The total length of FITC-Labeled HGFR Protein, Human (HEK293, His) is 908 a.a., with molecular weight of 30-40 kDa & 90-100 kDa & 150 kDa, respectively.
  • HY-P70714
    HGFR Protein, Human (HEK293, His)

    Hepatocyte growth factor receptor; HGF receptor; HGF/SF receptor; Proto-oncogene c-Met; Scatter factor receptor; SF receptor; Tyrosine-protein kinase Met; MET

    Human HEK293
    The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. HGFR Protein, Human (HEK293, His) is the recombinant human-derived HGFR protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P72376
    HGFR Protein, Human (Biotinylated, HEK293, His-Avi)

    Hepatocyte growth factor receptor; Proto-oncogene c-Met; SF receptor; Tyrosine-protein kinase Met; MET

    Human HEK293
    The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. HGFR Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived HGFR protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag.
  • HY-P72624
    HGFR Protein, Human (495a.a, HEK293, His)

    Hepatocyte growth factor receptor; HGF receptor; SF receptor; MET

    Human HEK293
    The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. HGFR Protein, Human (495a.a, HEK293, His) is the recombinant human-derived HGFR protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P72935
    HGFR Protein, Cynomolgus/Rhesus Macaque (HEK293)

    Hepatocyte growth factor receptor; HGF receptor; SF receptor; MET

    Rhesus Macaque; Cynomolgus HEK293
    HGFR Protein, a receptor tyrosine kinase, transduces signals by binding hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. Upon ligand binding, HGFR undergoes autophosphorylation, creating docking sites for downstream molecules like PI3K, PLCG1, SRC, GRB2, STAT3, or GAB1, activating RAS-ERK, PI3K-AKT, and PLCgamma-PKC cascades. HGFR Protein, Cynomolgus/Rhesus Macaque (HEK293) is the recombinant Rhesus Macaque, cynomolgus-derived HGFR protein, expressed by HEK293 , with tag free. The total length of HGFR Protein, Cynomolgus/Rhesus Macaque (HEK293) is 908 a.a., with molecular weight of 73-93 kDa.
Cat. No. Product Name Effect Purity