HGF
Hepatocyte growth factor (HGF, also known as Scatter Factor) is among a group of factors possessing angiogenic ability. HGF was originally discovered as a fibroblast-derived cell motility factor for epithelial cells. It is synthesized by mesenchymal cells, fibroblasts, and smooth muscle cells. Active HGF is a heterodimer consists of a heavy chain (α chain, 62 kDa) and a light chain (β chain, 32-36 kDa), which are covalently linked by a disulfide bridge. HGF exerts its biological functions (i.e., proliferation/differentiation/survival/motogenesis) mediated by binding to the c-Met receptor. The HGF/c-Met signaling axis contributes in a paracrine manner to the development of epithelial organs, exerts regenerative effects on the epithelium, and promotes the regression of fibrosis in numerous organs. Additionally, the HGF/c-Met signaling pathway is correlated with the biology of cancer, neurons and immunity.
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HGF Recombinant Proteins (11)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 1
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
