2. Recombinant Proteins
  3. Kinases
  4. TK

TK

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Cat. No. Product Name / Synonyms Species Source Image
  • HY-P73422
    Src Protein, Human (Active, sf9, His-GST)

    Proto-oncogene tyrosine-protein kinase Src; Src; p60-Src; SRC1

    		Human Sf9 insect cells
    Src is a non-receptor protein tyrosine kinase that centralizes multiple cellular processes triggered by various receptors. It controls gene transcription, immune response, adhesion, cell cycle, apoptosis, migration and transformation. Src Protein, Human (sf9, His-GST) is the recombinant human-derived Src protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
    (1)
  • HY-P72938
    HGFR Protein, Human (Active, sf9, His-GST)

    Hepatocyte growth factor receptor; HGF receptor; SF receptor; MET

    		Human Sf9 insect cells
    The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. HGFR Protein, Human (sf9, His-GST) is the recombinant human-derived HGFR protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
    (1)
  • HY-P72987
    EGFR Protein, Human (Active, sf9, His-GST)

    Epidermal growth factor receptor; EGFR; ERBB; ERBB1; HER1

    		Human Sf9 insect cells
    EGFR is a transmembrane glycoprotein. EGFR binds to ligands, triggering receptor dimerization, inducing intracellular TK domain autophosphorylation, activating downstream Ras/MAPK, PI3K/Akt and other signaling pathways, and regulating cell proliferation, survival, migration and angiogenesis. EGFR Protein, Human (sf9, His-GST) is a recombinant EGFR protein expressed by Sf9 insect cells with N-His, N-GST tags.
  • HY-P72991
    EphA2 Protein, Human (Active, sf9, His-GST)

    Ephrin type-A receptor 2; Epithelial cell kinase; EPHA2; ECK

    		Human Sf9 insect cells
    EphA2 protein is a receptor tyrosine kinase that participates in bidirectional signaling with various ephrin A ligands, affecting cell migration, adhesion, proliferation and differentiation. It regulates cell adhesion and differentiation by interacting with DSG1 and inhibiting the ERK1/ERK2 signaling pathway. EphA2 Protein, Human (sf9, His-GST) is the recombinant human-derived EphA2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
    (1)
  • HY-P73283
    LYNa Protein, Human (Active, sf9, GST)

    Hck-2; JTK8; Tyrosine-protein kinase Lyn

    		Human Sf9 insect cells
    Lyn protein is a non-receptor tyrosine protein kinase that centrally mediates signals from diverse cell surface receptors, regulating immune responses, hematopoiesis, and integrin signaling. It acts as a negative or positive regulator depending on the context, affecting B cell responses, differentiation and inflammatory responses. LYNa Protein, Human (Active, sf9, GST) is the recombinant human-derived LYNa protein, expressed by Sf9 insect cells , with N-GST labeled tag.
    (1)
  • HY-P73390
    ROR1 Protein, Human (sf9, His)

    Inactive tyrosine-protein kinase transmembrane receptor ROR1; ROR1; NTRKR1

    		Human Sf9 insect cells
    ROR1 protein's minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo. It serves as a receptor for WNT5A, activating NFkB signaling and potentially inhibiting WNT3A signaling. Notably, ROR1 plays a vital role in the inner ear, facilitating innervation of auditory hair cells by spiral ganglion neurons. ROR1 Protein, Human (sf9, His) is the recombinant human-derived ROR1 protein, expressed by Sf9 insect cells , with C-His labeled tag.
  • HY-P73678
    RET Protein, Human (Active, sf9, His-GST)

    Proto-oncogene tyrosine-protein kinase receptor Ret; RET; CDHF12; CDHR16

    		Human Sf9 insect cells
    RET protein is a receptor tyrosine protein kinase that plays a key role in cell proliferation, neuronal navigation, and differentiation upon binding to glial cell-derived neurotrophic factor family ligands. It regulates the delicate balance between cell death and survival, influences positional information, and is critical for intestinal organogenesis, enteric nervous system development, renal organogenesis, and Peyer's patch formation. RET Protein, Human (sf9, His-GST) is the recombinant human-derived RET protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
  • HY-P73244
    Insulin R/CD220 Protein, Human (Active, sf9, His-GST)

    CD 220; HHF5; INSR; Insulin R; Insulin receptor; IR

    		Human Sf9 insect cells
    The insulin R/CD220 protein is a receptor tyrosine kinase that coordinates insulin action by phosphorylating substrates such as IRS and SHC upon insulin binding. Phosphorylated IRS activates PI3K-AKT/PKB to exert metabolic effects, and activates Ras-MAPK to promote growth and differentiation. Insulin R/CD220 Protein, Human (sf9, His-GST) is the recombinant human-derived Insulin R/CD220 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
    (1)
  • HY-P73269
    Lck Protein, Human (Active, sf9, GST)

    Tyrosine-protein kinase Lck; LSK; LCK; Hck-3

    		Human Sf9 insect cells
    The Lck protein is a non-receptor tyrosine protein kinase that is essential for T cell development and function. Lck is constitutively associated with CD4 and CD8 receptors and is recruited to the TCR/CD3 complex following TCR interaction with MHC. Lck Protein, Human (sf9, GST) is the recombinant human-derived Lck protein, expressed by Sf9 insect cells , with N-GST labeled tag.
    (1)
  • HY-P73423
    Src Protein, Mouse (Active, sf9, His-GST)

    Proto-oncogene tyrosine-protein kinase Src; Src; p60-Src; SRC1

    		Mouse Sf9 insect cells
    Src, a non-receptor protein tyrosine kinase, displays a unique ability to phosphorylate synaptophysin with high affinity.Src Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived Src protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
  • HY-P72196
    FGFR-3 Protein, Human (His-B2M)

    ACH; CD 333; CD333; CD333 antigen; CEK 2; CEK2; FGFR 3; FGFR-3; FGFR3; FGFR3_HUMAN; Fibroblast growth factor receptor 3 achondroplasia thanatophoric dwarfism; ; Fibroblast growth factor receptor 3; Heparin binding growth factor receptor; HSFGFR3EX; Hydroxyaryl protein kinase; JTK 4; JTK4; MFR 3; SAM 3; Tyrosine kinase JTK 4; Tyrosine kinase JTK4; Z FGFR 3

    		Human E. coli
    The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 Protein, Human (His-B2M) is the recombinant human-derived FGFR-3 protein, expressed by E. coli , with N-6*His, N-B2M labeled tag.
  • HY-P77308
    ABL1 Protein, Human (Active, sf9, GST)

    Abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine protein kinase 1; Abl 1; ABL; JTK7; p150; Proto oncogene tyrosine protein kinase ABL1

    		Human Sf9 insect cells
    ABL1 is a non-receptor tyrosine protein kinase that coordinates key cellular processes for growth and survival. It affects cytoskeletal remodeling, cell motility, and receptor endocytosis. ABL1 Protein, Human (sf9, GST) is the recombinant human-derived ABL1 protein, expressed by Sf9 insect cells , with N-GST labeled tag.
    (1)
  • HY-P7989
    Janus kinase 2/JAK2 Protein, Human (His)

    JAK2, Janus kinase 2

    		Human E. coli
    Janus kinase 2/JAK2 Protein, Human (His) is a recombinant human JAK2 expressed in E. coli with a His tag at the N-terminus. JAK2 is a non-receptor tyrosine kinase.
    (1)
  • HY-P75542
    ACK1 Protein, Human (Active, sf9, GST)

    Activated CDC42 kinase 1; Tyrosine kinase non-receptor protein 2; TNK2

    		Human Sf9 insect cells
    The ACK1 protein is a non-receptor tyrosine protein and serine/threonine protein kinase that orchestrates cellular physiology by affecting cell spreading, migration, survival, growth, and proliferation. It phosphorylates AKT1, AR, MCF2, WASL and WWOX, affecting various cellular processes. ACK1 Protein, Human (sf9, GST) is the recombinant human-derived ACK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag.
    (1)
  • HY-P74795
    ITK Protein, Mouse (sf9, His-GST)

    Tyrosine-protein kinase ITK/TSK; IL-2-inducible T-cell kinase; ITK; EMT; LYK

    		Mouse Sf9 insect cells
    ITK protein is a tyrosine kinase that plays a crucial role in directing adaptive immune responses by controlling the development, function, and differentiation of conventional T cells and unconventional NKT cells.After T cell receptor (TCR) activation by antigen-presenting cells (APC), ITK is recruited to the cell membrane and phosphorylated by LCK, thereby making it fully activated.ITK Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived ITK protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
  • HY-P78739
    JAK1 Protein, Human (Inactive, sf9, His)

    JAK1; JAK-1; JAK1A; JAK1B; Jak1

    		Human sf9 insect cells
    JAK1 protein is a non-receptor tyrosine kinase that plays a crucial role in IFN-α/β/γ signaling and serves as a kinase partner for IL-2 and IL-10 receptors. It cooperates with the type I interferon receptor IFNAR2 to phosphorylate and activate IFNAR2 upon interferon binding to IFNAR1-IFNAR2. JAK1 Protein, Human (Inactive, sf9, His) is the recombinant human-derived JAK1 protein, expressed by sf9 insect cells , with N-His labeled tag.
    (1)
  • HY-P700583
    JAK1 Protein, Human (P. pastoris, His)

    JAK1; JAK1A; JAK1B; Tyrosine-protein kinase JAK1; Janus kinase 1; JAK-1

    		Human P. pastoris
    JAK1 protein is a non-receptor tyrosine kinase that plays a crucial role in IFN-α/β/γ signaling and serves as a kinase partner for IL-2 and IL-10 receptors. It cooperates with the type I interferon receptor IFNAR2 to phosphorylate and activate IFNAR2 upon interferon binding to IFNAR1-IFNAR2. JAK1 Protein, Human (P. pastoris, His) is the recombinant human-derived JAK1 protein, expressed by P. pastoris , with N-6*His labeled tag.
  • HY-P701102
    Janus kinase 2/JAK2 Protein, Human (381a.a, His)

    JAK 2; JAK-2; JAK2; JAK2_HUMAN; Janus Activating Kinase 2; Janus kinase 2 (a protein tyrosine kinase); Janus kinase 2; JTK 10; JTK10; kinase Jak2; OTTHUMP00000043260; THCYT3; Tyrosine protein kinase JAK2; Tyrosine-protein kinase JAK2

    		Human E. coli
    Janus kinase 2/JAK2 Protein, Human is a recombinant human JAK2 expressed in E. coli with a His tag at the N-terminus. JAK2 is a non-receptor tyrosine kinase.
  • HY-P701643
    TEC Protein, Human (Active, sf9, GST)

    TEC; Tyrosine-protein kinase Tec

    		Human Sf9 insect cells
    TEC proteins are dynamic nonreceptor tyrosine kinases that transduce signals in a variety of cellular processes. In adaptive immunity, TEC regulate T cell development, affecting IL2 gene induction and CD28 signaling. TEC Protein, Human (sf9, GST) is the recombinant human-derived TEC protein, expressed by sf9 insect cells , with N-GST labeled tag.
  • HY-P701682
    FAK1 Protein, Human (Active, sf9, GST)

    PTK2; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK

    		Human Sf9 insect cells
    FAK1 is a nonreceptor protein tyrosine kinase that coordinates multiple cellular processes. FAK1 Protein, Human (sf9, GST) is the recombinant human-derived FAK1 protein, expressed by sf9 insect cells , with N-GST labeled tag.
Cat. No. Product Name Effect Purity