1. Recombinant Proteins
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Selectin

Selectins are cell membrane glycoproteins which mediate cell-cell adhesion by recognizing carbohydrates presented on the cell surface. Selectins bind carbohydrate ligands in a Ca2+-dependent manner. They are expressed on platelets (P-selectins/CD62L), leukocytes (L-selectins/CD62P) and endothelial cells (E- and P-selectins/CD62E). Selectins belong to a group of adhesion molecules mediate adhesion of hematopoietic and cancer cells to endothelial cells, leukocytes, and platelets in flowing blood. These adhesion events play a crucial role in inflammation, infection, cancer, lymphocyte and bone marrow stem cell homing, and immune cell surveillance. Selectins also assist homing of aberrant leukocytes in chronic and acute inflammatory diseases.

Cat. No. Product Name / Synonyms Species Source
  • HY-P74161
    E-Selectin/CD62E Protein, Human (HEK293, His-Fc)

    E-selectin; ELAM-1; LECAM2; CD62E; SELE

    Human HEK293
    E-selectin/CD62E Protein, a cell-surface glycoprotein, crucially mediates immunoadhesion by interacting with SELPLG/PSGL1 for the adhesion of neutrophils to cytokine-activated endothelium. It also potentially influences capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2 through the sialyl Lewis X epitope, independently of SELPLG sulfation. E-Selectin/CD62E Protein, Human (HEK293, His-Fc) is the recombinant human-derived E-Selectin/CD62E protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of E-Selectin/CD62E Protein, Human (HEK293, His-Fc) is 535 a.a., with molecular weight of 140-150 kDa.
  • HY-P78119
    E-selectin/CD62E Protein, Human (Biotinylated, HEK293, His-Avi)

    CD62E; ELAM; ELAM1; ESEL; E-Selectin; LECAM2; SELE; selectin E; RP1-117P20.2

    Human HEK293
    E-selectin/CD62E Protein, a cell-surface glycoprotein, crucially mediates immunoadhesion by interacting with SELPLG/PSGL1 for the adhesion of neutrophils to cytokine-activated endothelium. It also potentially influences capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2 through the sialyl Lewis X epitope, independently of SELPLG sulfation. E-selectin/CD62E Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived E-selectin/CD62E protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of E-selectin/CD62E Protein, Human (Biotinylated, HEK293, His-Avi) is 535 a.a., with molecular weight of 80-100 kDa.
  • HY-P78201
    P-Selectin Protein, Human (Biotinylated, HEK293, His-Avi)

    FLJ45155; GMP140; GRMP; PADGEM; PSEL; P-Selectin; SELP; CD62P; CD62; LECAM3

    Human HEK293
    P-selectin, a Ca(2+)-dependent receptor on myeloid cells, crucially binds to sialyl-Lewis X on neutrophils and monocytes, facilitating the interaction of activated endothelial cells or platelets with leukocytes. This engagement, primarily with SELPLG/PSGL1 and PODXL2, is vital for the rapid rolling of leukocytes during early inflammation. P-selectin's interactions with SNX17 further mediate neutrophil adhesion and rolling, dependent on the sialyl-Lewis X epitope and specific tyrosine sulfation on SELPLG. P-Selectin Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived P-Selectin protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of P-Selectin Protein, Human (Biotinylated, HEK293, His-Avi) is 730 a.a., with molecular weight of 115-140 kDa.
  • HY-P70803
    P-selectin Protein, Human (HEK293, His)

    P-selectin; CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; PADGEM

    Human HEK293
    P-selectin is a Ca(2+)-dependent receptor on myeloid cells that critically binds to sialic acid-Lewis X on neutrophils and monocytes, promoting the interaction between activated endothelial cells or platelets and leukocytes interaction. This binding primarily to SELPLG/PSGL1 and PODXL2 is critical for rapid rolling of leukocytes during early inflammation. P-selectin Protein, Human (HEK293, His) is the recombinant human-derived P-selectin protein, expressed by HEK293 , with C-His labeled tag. The total length of P-selectin Protein, Human (HEK293, His) is 730 a.a., with molecular weight of 95-130 kDa.
  • HY-P72661
    E-selectin/CD62E Protein, Human (HEK293, His)

    E-selectin; ELAM-1; LECAM2; CD62E; SELE

    Human HEK293
    E-selectin/CD62E Protein, a cell-surface glycoprotein, crucially mediates immunoadhesion by interacting with SELPLG/PSGL1 for the adhesion of neutrophils to cytokine-activated endothelium. It also potentially influences capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2 through the sialyl Lewis X epitope, independently of SELPLG sulfation. E-selectin/CD62E Protein, Human (HEK293, His) is the recombinant human-derived E-selectin/CD62E protein, expressed by HEK293 , with C-6*His labeled tag. The total length of E-selectin/CD62E Protein, Human (HEK293, His) is 535 a.a., with molecular weight of ~104 kDa.
  • HY-P73383
    P-Selectin Protein, Mouse (HEK293, Fc)

    P-selectin; GMP-140; LECAM3; PADGEM; CD62P; Selp

    Mouse HEK293
    P-selectin is a Ca(2+)-dependent receptor on myeloid cells that specifically binds to carbohydrates on neutrophils and monocytes. It mediates interactions between activated endothelial cells or platelets and leukocytes by recognizing sialic acid-Lewis X. P-Selectin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived P-Selectin protein, expressed by HEK293 , with C-hFc labeled tag. The total length of P-Selectin Protein, Mouse (HEK293, Fc) is 668 a.a., with molecular weight of ~135 kDa.
  • HY-P70312
    L-selectin/CD62L Protein, Mouse (294a.a, HEK293, C-Fc-His)

    rMuL-selectin, His; L-selectin; Sell; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LECAM1; Lymph node homing receptor; Lymphocyte antigen 22; CD62L

    Mouse HEK293
    L-selectin, a calcium-dependent lectin, binds to glycoproteins on adjacent cells, facilitating lymphocyte attachment to endothelial cells in peripheral lymph nodes. This interaction is essential for leukocyte rolling along the endothelium and requires L-selectin's binding to SELPLG/PSGL1 and PODXL2, dependent on glycan and sulfation modifications. Sulfation of 'Tyr-51' on SELPLG is particularly important for L-selectin binding. L-selectin/CD62L Protein, Mouse (294a.a, HEK293, C-Fc-His) is the recombinant mouse-derived L-selectin/CD62L protein, expressed by HEK293 , with C-6*His, C-Fc labeled tag. The total length of L-selectin/CD62L Protein, Mouse (294a.a, HEK293, C-Fc-His) is 294 a.a., with molecular weight of 90-120 kDa.
  • HY-P72408
    P-selectin Protein, Mouse (Biotinylated, HEK293, Avi-His)

    CD62 antigen-like family member P; GMP-140; LECAM3; PADGEM

    Mouse HEK293
    P-selectin is a Ca(2+)-dependent receptor on myeloid cells that specifically binds to carbohydrates on neutrophils and monocytes. It mediates interactions between activated endothelial cells or platelets and leukocytes by recognizing sialic acid-Lewis X. P-selectin Protein, Mouse (Biotinylated, HEK293, Avi-His) is the recombinant mouse-derived P-selectin protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of P-selectin Protein, Mouse (Biotinylated, HEK293, Avi-His) is 668 a.a., with molecular weight of 102-122 kDa.
  • HY-P73042
    E-Selectin/CD62E Protein, Mouse (HEK293, His)

    E-selectin; ELAM-1; LECAM2; CD62E; SELE

    Mouse HEK293
    E-Selectin/CD62E protein, a cell-surface glycoprotein, mediates the adhesion of blood neutrophils to cytokine-activated endothelium through interaction with SELPLG/PSGL1. It also potentially contributes to capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2. These multifaceted interactions highlight E-Selectin's role in cell adhesion and its potential influence on vascular development. E-Selectin/CD62E Protein, Mouse (HEK293, His) is the recombinant mouse-derived E-Selectin/CD62E protein, expressed by HEK293 , with C-His, C-10*His labeled tag. The total length of E-Selectin/CD62E Protein, Mouse (HEK293, His) is 536 a.a., with molecular weight of 70-110 kDa.
  • HY-P73044
    E-Selectin/CD62E Protein, Rat (HEK293, His)

    E-selectin; ELAM-1; LECAM2; CD62E; SELE

    Rat HEK293
    The E-selectin/CD62E protein is a cell surface glycoprotein that critically mediates immune adhesion by promoting neutrophil adhesion to cytokine-activated endothelial cells through the SELPLG/PSGL1 interaction. It may also contribute to capillary morphogenesis and interact with SELPLG/PSGL1 and PODXL2 via the sialyl Lewis X epitope regardless of SELPLG sulfation. E-Selectin/CD62E Protein, Rat (HEK293, His) is the recombinant rat-derived E-Selectin/CD62E protein, expressed by HEK293 , with C-His labeled tag. The total length of E-Selectin/CD62E Protein, Rat (HEK293, His) is 473 a.a., with molecular weight of ~75-96 kDa.
  • HY-P74768
    L-selectin/CD62L Protein, Human (HEK293, His)

    L-selectin; Sell; CD62 antigen-like family member L; LECAM1; CD62L; LAM-1

    Human HEK293
    L-Selectin, also known as CD62L, is a calcium-dependent lectin that plays a crucial role in mediating cell adhesion by binding to glycoproteins on neighboring cells. Functionally, it facilitates the adherence of lymphocytes to endothelial cells within high endothelial venules in peripheral lymph nodes, promoting the initial tethering and rolling of leukocytes in endothelial tissues. L-Selectin's interaction with SELPLG/PSGL1 and PODXL2 is vital for the recruitment and rolling of leukocytes. This interaction is specifically dependent on the sialyl Lewis X glycan modification of SELPLG and PODXL2, along with tyrosine sulfation modifications of SELPLG. Notably, sulfation on 'Tyr-51' of SELPLG emerges as a critical factor for effective L-Selectin binding. The multifaceted functions of L-Selectin underscore its significance in orchestrating cell adhesion processes and immune cell recruitment. L-selectin/CD62L Protein, Human (HEK293, His) is the recombinant human-derived L-selectin/CD62L protein, expressed by HEK293 , with C-His labeled tag. The total length of L-selectin/CD62L Protein, Human (HEK293, His) is 294 a.a., with molecular weight of 50-75 kDa.
  • HY-P73689
    P-Selectin Protein, Rat (HEK293, His)

    P-selectin; GMP-140; LECAM3; PADGEM; CD62P; Selp

    Rat HEK293
    P-Selectin, a Ca(2+)-dependent receptor on myeloid cells, binds to neutrophils and monocytes via carbohydrates. It interacts with SELPLG to enable rapid leukocyte rolling over vascular surfaces in early inflammation. P-Selectin also interacts with SNX17 and promotes neutrophil adhesion and rolling, requiring SELPLG's sialyl-Lewis X and tyrosine sulfation. P-Selectin Protein, Rat (HEK293, His) is the recombinant rat-derived P-Selectin protein, expressed by HEK293 , with C-His labeled tag. The total length of P-Selectin Protein, Rat (HEK293, His) is 659 a.a., with molecular weight of ~115 kDa.
  • HY-P75220
    E-selectin/CD62E Protein, Cynomolgus (HEK293, His)

    E-selectin; ELAM-1; LECAM2; CD63E; SELE

    Cynomolgus HEK293
    The E-selectin/CD62E Protein, belonging to the selectin/LECAM family, plays a crucial role in mediating cell adhesion processes, particularly interactions between leukocytes and endothelial cells. As a member of this family, E-selectin likely shares conserved features, emphasizing its significance in cellular adhesion. Its study contributes to understanding inflammatory responses, immune cell trafficking, and potential therapeutic interventions. Further exploration of E-selectin/CD62E's role promises insights into its contributions to immune surveillance, inflammation, and broader cellular processes in both normal physiology and pathology. E-selectin/CD62E Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived E-selectin/CD62E protein, expressed by HEK293, with C-His labeled tag. The total length of E-selectin/CD62E Protein, Cynomolgus (HEK293, His) is 535 a.a., with molecular weight of 95-115 kDa.
  • HY-P76638
    L-Selectin/CD62L Protein, Rat (HEK293, His)

    L-selectin; LAM-1; LECAM1; TQ1; gp90-MEL; CD62L; SELL; LNHR; LYAM1

    Rat HEK293
    L-Selectin/CD62L, a calcium-dependent lectin, binds adjacent glycoproteins, enabling lymphocyte adherence to endothelial cells in peripheral lymph nodes. This promotes leukocyte tethering and rolling within endothelial tissues. Interaction with SELPLG/PSGL1 and PODXL2, including glycan and sulfation modifications, is crucial for leukocyte recruitment and rolling. Particularly, sulfation on 'Tyr-51' of SELPLG is vital for L-Selectin binding, emphasizing its role in cellular interactions and adhesion. L-Selectin/CD62L Protein, Rat (HEK293, His) is the recombinant rat-derived L-Selectin/CD62L protein, expressed by HEK293, with C-His labeled tag. The total length of L-Selectin/CD62L Protein, Rat (HEK293, His) is 294 a.a., with molecular weight of ~34.8 kDa.
  • HY-P77483
    L-selectin/CD62L Protein, Cynomolgus (HEK293, His)

    L-selectin; Sell; CD62 antigen-like family member L; LECAM1; CD62L; LAM-1

    Cynomolgus HEK293
    L-selectin/CD62L is a calcium-dependent lectin that aids cell adhesion by binding to neighboring glycoproteins. It mediates lymphocyte adhesion to endothelial cells in peripheral lymph nodes, causing leukocytes to tether and roll. L-selectin/CD62L Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived L-selectin/CD62L protein, expressed by HEK293 , with C-His labeled tag. The total length of L-selectin/CD62L Protein, Cynomolgus (HEK293, His) is 304 a.a., with molecular weight of 52-63 kDa.
  • HY-P73687
    P-Selectin Protein, Rhesus Macaque (HEK293, His)

    P-selectin; GMP-140; LECAM3; PADGEM; CD62P; Selp

    Rhesus Macaque HEK293
    P-Selectin Protein, Rhesus Macaque (HEK293, His) is a member of the selectin family of cell adhesion molecules. P-selectin (CD62P) has an N-terminal lectin domain, an epidermal growth factor motif, (generally) nine regulatory protein repeats, a transmembrane section and a short intracytoplasmic tail. P-selectin mediates leukocyte rolling on stimulated endothelial cells and heterotypic aggregation of activated platelets onto leukocytes. P-selectin mediates heterotypic aggregation of activated platelets to cancer cells and adhesion of cancer cells to stimulated endothelial cells. P-selectin glycoprotein ligand-1 (PSGL-1) is a major ligand for P-selectin. P-Selectin Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived P-Selectin protein, expressed by HEK293 , with C-His labeled tag. The total length of P-Selectin Protein, Rhesus Macaque (HEK293, His) is 730 a.a., with molecular weight of ~81.2 kDa.
  • HY-P73690
    P-Selectin Protein, Human (HEK293, Fc)

    P-selectin; GMP-140; LECAM3; PADGEM; CD62P; Selp

    Human HEK293
    P-selectin, a Ca(2+)-dependent receptor on myeloid cells, crucially binds to sialyl-Lewis X on neutrophils and monocytes, facilitating the interaction of activated endothelial cells or platelets with leukocytes. This engagement, primarily with SELPLG/PSGL1 and PODXL2, is vital for the rapid rolling of leukocytes during early inflammation. P-selectin's interactions with SNX17 further mediate neutrophil adhesion and rolling, dependent on the sialyl-Lewis X epitope and specific tyrosine sulfation on SELPLG. P-Selectin Protein, Human (HEK293, Fc) is the recombinant human-derived P-Selectin protein, expressed by HEK293, with C-hFc labeled tag. The total length of P-Selectin Protein, Human (HEK293, Fc) is 730 a.a., with molecular weight of 130-150 kDa.
  • HY-P74765
    L-selectin/CD62L Protein, Mouse (HEK293, His-hFc)

    L-selectin; Sell; CD62 antigen-like family member L; LECAM1; CD62L; LAM-1

    Mouse HEK293
    L-selectin, a calcium-dependent lectin, binds to glycoproteins on adjacent cells, facilitating lymphocyte attachment to endothelial cells in peripheral lymph nodes. This interaction is essential for leukocyte rolling along the endothelium and requires L-selectin's binding to SELPLG/PSGL1 and PODXL2, dependent on glycan and sulfation modifications. Sulfation of 'Tyr-51' on SELPLG is particularly important for L-selectin binding. L-selectin/CD62L Protein, Mouse (HEK293, His-hFc) is the recombinant mouse-derived L-selectin/CD62L protein, expressed by HEK293, with C-hFc, C-His labeled tag. The total length of L-selectin/CD62L Protein, Mouse (HEK293, His-hFc) is 332 a.a., with molecular weight of 100-110 kDa.
  • HY-P78437
    E-Selectin/CD62E Protein, Human (HEK293, His-Avi)

    CD62E; ELAM; ELAM1; ESEL; E-Selectin; LECAM2; SELE; selectin E; RP1-117P20.2

    Human HEK293
    E-selectin/CD62E Protein, a cell-surface glycoprotein, crucially mediates immunoadhesion by interacting with SELPLG/PSGL1 for the adhesion of neutrophils to cytokine-activated endothelium. It also potentially influences capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2 through the sialyl Lewis X epitope, independently of SELPLG sulfation. E-Selectin/CD62E Protein, Human (HEK293, His-Avi) is the recombinant human-derived E-Selectin/CD62E protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of E-Selectin/CD62E Protein, Human (HEK293, His-Avi) is 535 a.a., with molecular weight of 80-100 kDa.
  • HY-P78511
    P-Selectin Protein, Human (HEK293, His-Avi)

    FLJ45155; GMP140; GRMP; PADGEM; PSEL; P-Selectin; SELP; CD62P; CD62; LECAM3

    Human HEK293
Cat. No. Product Name Effect Purity