Selectin
Selectins are cell membrane glycoproteins which mediate cell-cell adhesion by recognizing carbohydrates presented on the cell surface. Selectins bind carbohydrate ligands in a Ca2+-dependent manner. They are expressed on platelets (P-selectins/CD62L), leukocytes (L-selectins/CD62P) and endothelial cells (E- and P-selectins/CD62E). Selectins belong to a group of adhesion molecules mediate adhesion of hematopoietic and cancer cells to endothelial cells, leukocytes, and platelets in flowing blood. These adhesion events play a crucial role in inflammation, infection, cancer, lymphocyte and bone marrow stem cell homing, and immune cell surveillance. Selectins also assist homing of aberrant leukocytes in chronic and acute inflammatory diseases.
-
Selectin Recombinant Proteins (28)
- 1
- 2
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 1
- 2
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
