CD3g
CD3g refers to the gamma chain of the CD3 complex, the product of the human CD3G gene. It contains an extracellular immunoglobulin-like domain, a single transmembrane region with an acidic residue that stabilizes association with the T cell receptor, and a cytoplasmic ITAM that couples antigen engagement to Lck and ZAP70 dependent phosphorylation. CD3g typically forms a heterodimer with CD3d, and loss of either partner prevents surface TCR-CD3 expression. CD3G defects therefore block T cell development and produce combined immunodeficiency. Because of its T lineage restriction, CD3g, together with CD3d and CD3e, is routinely used for T cell immunophenotyping.
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CD3g Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
