1. PROTAC
  2. PROTAC Linker

PROTAC Linker

The PROTAC linker connects two moieties: a small peptide residue for E3 ubiquitin ligase recognition,and a ligand that can be recognized by a targeted protein.

Unlike the small molecule ligands, the length of the linker has been randomly selected for PROTACs, varying from 12-carbon to over 20-carbon in length. An optimal linker will allow for maximal interaction between the two moieties (target protein and E3 ligase) resulting in efficient ubiquitination of the target protein and its ultimate degradation.

PROTAC Linker Related Products (1):

Cat. No. Product Name Effect Purity
  • HY-108370
    N33-TEG-COOH
    N33-TEG-COOH is a PROTAC linker containing four polyethylene glycol (PEG) units.
Isoform Specific Products

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.