Boc-NH-PEG3
Based on 1 Customer Validation
Boc-NH-PEG3 (PROTAC Linker 10) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 139115-92-7
- Formula: C11H23NO5
- Molecular Weight:249.30
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 139115-92-7
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Appearance Liquid (Density: 1.071±0.06 g/cm3)
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Molecular Weight 249.30
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Formula C11H23NO5
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)NCCOCCOCCO
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Synonyms
PROTAC Linker 10
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (401.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0112 mL | 20.0562 mL | 40.1123 mL | 100.2808 mL |
| 5 mM | 0.8022 mL | 4.0112 mL | 8.0225 mL | 20.0562 mL | |
| 10 mM | 0.4011 mL | 2.0056 mL | 4.0112 mL | 10.0281 mL | |
| 15 mM | 0.2674 mL | 1.3371 mL | 2.6742 mL | 6.6854 mL | |
| 20 mM | 0.2006 mL | 1.0028 mL | 2.0056 mL | 5.0140 mL | |
| 25 mM | 0.1604 mL | 0.8022 mL | 1.6045 mL | 4.0112 mL | |
| 30 mM | 0.1337 mL | 0.6685 mL | 1.3371 mL | 3.3427 mL | |
| 40 mM | 0.1003 mL | 0.5014 mL | 1.0028 mL | 2.5070 mL | |
| 50 mM | 0.0802 mL | 0.4011 mL | 0.8022 mL | 2.0056 mL | |
| 60 mM | 0.0669 mL | 0.3343 mL | 0.6685 mL | 1.6713 mL | |
| 80 mM | 0.0501 mL | 0.2507 mL | 0.5014 mL | 1.2535 mL | |
| 100 mM | 0.0401 mL | 0.2006 mL | 0.4011 mL | 1.0028 mL |
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