1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Neurotrophic Factors
  4. Neurotrophins/NGF

The neurotrophin family (Neurotrophins, NTs) is a family of structurally and functionally related peptides which regulates neural survival, development, function, and plasticity. In mammals, NTs consists of nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), NT-4/5. Two additional members, NT-6 and NT-7 have been identified only in fish, but mammalian homologs have not yet been identified. NTs mediate their actions by binding to 2 classes of receptors, the tropomyosin receptor kinase (trk) family of receptor tyrosine kinases, and a member of the tumour necrosis factor (TNF)-α family of receptors, p75. NGF binds TrkA, BDNF and NT-4 bind TrkB, and NT-3 binds TrkA, TrkB, and TrkC. In addition, all NTs activate p75 with low affinity, enhancing the activation of Trk receptors. Through these, NTs activate many signaling pathways, including those mediated by ras and members of the cdc-42/ras/rho G protein families, and the MAP kinase, PI-3 kinase, and Jun kinase cascades.

Cat. No. Product Name / Synonyms Species Source
  • HY-P7116A
    BDNF Protein, Human

    rHuBDNF/Brain-derived neurotrophic factor; Abrineurin

    Human E. coli
    BDNF Protein, Human is a neurotrophin binding to the high-affinity tropomyosin-related receptor kinase B (TrkB) receptor to regulate neurodevelopmental processes, including neuronal survival, neuronal differentiation, and synaptic plasticity.
  • HY-P7661
    Beta-NGF Protein, Mouse (120a.a)

    rMuBeta-NGF; Beta-nerve growth factor; Beta-NGF;

    Mouse E. coli
    Beta-NGF Protein, Mouse (120a.a) expresses in E. coli. Beta-Nerve Growth Factor is an important member of the NGF family, which displays the biological activity of NGF.
  • HY-P7660
    Beta-NGF Protein, Human (HEK293)

    rHuBeta-NGF; Beta-Nerve Growth Factor; Beta-NGF;

    Human HEK 293
    Beta-NGF Protein, Human (HEK293) is recombinant human beta-nerve growth factor produced in HEK293 cells. Beta-NGF Protein plays a major role in bone remodeling.
  • HY-P70456
    Neurotrophin-3 Protein, Human

    Neurotrophin-3; NT-3; HDNF; Nerve Growth Factor 2; NGF-2; Neurotrophic Factor; NTF3

    Human E. coli
    Neurotrophin-3 Protein, Human is a recombinant Neurotrophin-3 protein expressed in E. coli system. Neurotrophin-3 is widely expressed in the nervous system. Neurotrophin-3 reduces cellular damage, improves neuronal regeneration in different models of lesions.
  • HY-P72489
    BDNF Protein, Human (R125A,R127A,R128A)

    Brain-derived neurotrophic factor; BDNF; Abrineurin; ProBDNF

    Human E. coli
  • HY-P70449
    Beta-NGF Protein, Human (120a.a)

    Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB

    Human E. coli
  • HY-P74383
    BDNF Protein, Mouse (R129A, R130A, HEK293, His)

    Brain-derived neurotrophic factor; BDNF; ProBDNF

    Mouse HEK293
  • HY-P70530
    Beta-NGF Protein, Mouse (110a.a)

    Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB

    Mouse E. coli
  • HY-P72488
    pro-Beta-NGF Protein, Human (223a.a)

    Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB

    Human E. coli
  • HY-P7271
    NGFR Protein, Human (HEK293)

    rHuNGFR; Gp80-LNGFR; p75 ICD; CD271; TNFRSF16

    Human HEK293
    NGFR Protein, Human (HEK293) is a member of tumor necrosis factor receptor superfamily, acts as a marker of cells with tumor-initiating capacity in multiple malignancies, including head and neck squamous cell carcinoma.
  • HY-P7272
    Neurotrophin-4 Protein, Human

    rHuNT-4; NT-5; NTF4; NTF5; NT4

    Human E. coli
    NT-4 Protein, Human is a member of neurotrophins family, binding with two distinct receptors: TrkB, high affinity receptor and p75 low-affinity neurotrophin receptor (p75NTR).
  • HY-P7273
    NT-4 Protein, Mouse

    rMuNT-4; NT-5; NTF4; NTF5

    Mouse E. coli
    NT-4 Protein, Mouse is a member of neurotrophins family, binding with two distinct receptors: TrkB, high affinity receptor and p75 low-affinity neurotrophin receptor (p75NTR).
  • HY-P73316
    Beta-NGF Protein, Human (CHO)

    Beta-NGF; Beta-Nerve Growth Factor; NGF; NGFB

    Human CHO
  • HY-P73317
    Beta-NGF Protein, Mouse (CHO)

    Beta-NGF; Beta-Nerve Growth Factor; NGF; NGFB

    Mouse CHO
  • HY-P73318
    NGFR Protein, Human (HEK293, Fc)

    NGFR; Gp80-LNGFR; p75 ICD; CD271; TNFRSF16

    Human HEK293
  • HY-P74699
    NGFR Protein, Rabbit (HEK293, His)

    NGFR; Gp80-LNGFR; p75 ICD; CD271; TNFRSF16

    Rabbit HEK293
  • HY-P74700
    NGFR Protein, Rabbit (HEK293, hFc)

    NGFR; Gp80-LNGFR; p75 ICD; CD271; TNFRSF16

    Rabbit HEK293
  • HY-P77102
    NGL-1/LRRC4C Protein, Human (HEK293, His)

    Leucine-rich repeat-containing protein 4C; Netrin-G1 ligand; KIAA1580; NGL1

    Human HEK 293
  • HY-P77103
    NGL-1/LRRC4C Protein, Mouse (HEK293, His)

    Leucine-rich repeat-containing protein 4C; Netrin-G1 ligand; KIAA1580; NGL1

    Mouse HEK 293
Cat. No. Product Name Effect Purity