2. Recombinant Proteins
  3. CD Antigens
  4. NK Cell CD Proteins

NK Cell CD Proteins

NK Cell CD Proteins

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The cluster of differentiation (CD) antigens a protocol used for the identification and investigation of cell surface molecules present on leukocytes. Some CD proteins often act as cell-cell or cell-matrix adhesion molecules, cytokine receptors, ion pores, or nutrient transporters. CD proteins play a variety of roles in immune system function. Natural killer (NK) cells are innate immune cells that show spontaneous cytolytic activity against cells under stress such as tumor cells and virus-infected cells. They are distinguished by their unique functions and expression of surface antigens. NK cells lack the clonotypic T cell receptor (TCR) of T and NKT cells and its associated signal-transducing adaptor, CD3ε. In humans, subsets of NK cells express the activating Fc receptor, CD16 and most express CD56 [neural cell adhesion molecule (NCAM) or Leu-19] . In C57BL/6 mice, NK cells are identified by the presence of NK1.1 (NKR-P1C) and NCR1 (NKp46/CD335), as well as CD49b (DX5, Integrin VLA-2α), are common NK cell markers in other mouse backgrounds.

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Cat. No. Product Name / Synonyms Species Source
  • HY-P70629
    IL-2R alpha Protein, Human (HEK293, Fc)

    IL-2R alpha; IL-2RA; IL-2 R alpha; Interleukin-2 receptor subunit alpha; CD25; p55; TAC antigen; IL2-RA; IL-2R subunit alpha; IL-2-RA; IL-2 receptor subunit alpha

    		Human HEK293
    IL-2R alpha Protein, Human (HEK293, Fc), a recombinant human IL-2RA produced in HEK293 cells, has an Fc fragment at the C-terminus. IL-2RA is a subunit of interleukin-2 receptor, plays a critical role in regulating the IL-2-mediated responses by modulating the affinity of the IL-2R for the ligand.
  • HY-P7374
    IL-2R alpha/CD25 Protein, Human (HEK293, Fc)

    rHuIL-2R α/CD25, Fc Chimera; TAC antigen; IL-2-RA; IL-2 R alpha; IL-2Rα; IL2RA

    		Human HEK293
    IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Human (HEK293, Fc) is a recombinant human IL-2R alpha protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 192 amino acids (E22-C213).
  • HY-P70807
    PVR/CD155 Protein, Human (HEK 293, His)

    Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS

    		Human HEK293
    PVR/CD155 Protein, Human (HEK 293, His) is a recombinant Human PVR expressed in HEK 293 cells with a His tag at the N-terminus. PVR, Human plays a role in cancer cell invasion and migration.
  • HY-P70824
    CD3 epsilon Protein, Human (27a.a, HEK293, Fc)

    T-Cell Surface Glycoprotein CD3 Epsilon Chain; T-Cell Surface Antigen T3/Leu-4 Epsilon Chain; CD3e; CD3E; T3E

    		Human HEK293
  • HY-P7168
    Fas/CD95 Protein, Human (HEK293)

    rHuFASR/TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Fas receptor; CD95; APT1; FAS1; Apo-1

    		Human HEK293
    Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293) has a full length of 157 amino acids (Q26-S172), produced in HEK293 cells with tag free.
  • HY-P72022
    SLAMF2/CD48 Protein, Human (194a.a, HEK293, hFc)

    B-lymphocyte activation marker BLAST-1 BCM1 surface antigen; Leukocyte antigen MEM-102; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2; TCT.1; CD48; BCM1; BLAST1;

    		Human HEK293
  • HY-P70506
    CD3 epsilon Protein, Human (HEK293, His)

    T-Cell Surface Glycoprotein CD3 Epsilon Chain; T-Cell Surface Antigen T3/Leu-4 Epsilon Chain; CD3e; CD3E; T3E

    		Human HEK293
  • HY-P70723
    LAG-3 Protein, Human (HEK293, Fc)

    Lymphocyte activation gene 3 protein; LAG3; LAG-3; Protein FDC; CD223

    		Human HEK293
  • HY-P70762
    CD28 Protein, Human/Cynomolgus (HEK 293, Fc)

    CD28; CD28 antigen; CD28 molecule; T-cell-specific surface glycoprotein CD28; Tp44; TP44

    		Human; Cynomolgus HEK293
  • HY-P7215
    IL-2R alpha/CD25 Protein, Human (191a.a, HEK293, His)

    rHuIL-2Rα, His; TAC-antigen; CD25

    		Human HEK293
    IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Human (191a.a, HEK293, His) is a recombinant human IL-2R alpha protein with a His tag at the C-terminus and is expressed in HEK293 cells. It consists of 191 amino acids (L23-C213).
  • HY-P72353
    CD28 Protein, Human/Cynomolgus (Biotinylated, HEK293, Fc-Avi)

    CD28; CD28 antigen; CD28 molecule; T-cell-specific surface glycoprotein CD28; Tp44; TP44

    		Human; Cynomolgus HEK293
  • HY-P72899
    CD3E-CD3G Heterodimer Protein, Human (HEK293, Fc-Flag & mFc)

    T-cell surface glycoprotein CD3 epsilon chain; CD3E; T3E; CD3 epsilon

    		Human HEK293
  • HY-P73319
    NKG2D/CD314 Protein, Human (sf9, His)

    CD314; KLRK1; NKG2-D type II integral membrane protein; NKG2D

    		Human Sf9 insect cells
  • HY-P75209
    Fc gamma RIIIA/CD16a Protein, Human (208a.a, F176V, HEK293, His)

    Low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3

    		Human HEK293
  • HY-P77710
    IL-18R alpha Protein, Human (HEK293, His-Avi)

    CD218a; IL18Ra; IL18R1; IL1RRP; IL-1 R5; IL-1 Rrp; IL-18 R alpha; IL-18 R1; IL-18Ra

    		Human HEK293
    IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18. IL-18R alpha Protein, Human (HEK293, His-Avi) is a recombinant protein with a His-Avi label that consists of 311 amino acids (A19-R329) and is produced by HEK293 cells.
  • HY-P77714
    IL-21R Protein, Human (217a.a, HEK293, Fc)

    IL-21 receptor; IL-21R; CD360; NILR

    		Human HEK293
  • HY-P7779
    LAMP1/CD107a Protein, Human (HEK293, Fc)

    rHuCD107a, C-Fc; Lysosome-Associated Membrane Glycoprotein 1; LAMP-1; Lysosome-Associated Membrane Protein 1; CD107 Antigen-Like Family Member A; CD107a; LAMP1

    		Human HEK293
    LAMP1/CD107a Protein, Human (HEK293, Fc) is a recombinant human CD107a expressed in HEK 293 cells with a C-Fc tag at the C-terminus. LAMP1/CD107a Protein can be used as a functional marker for the identification of natural killer cell activity.
  • HY-P7780
    Nectin-2/CD112 Protein, Human (HEK293, His)

    rHuCD112, His; Poliovirus Receptor-Related Protein 2; Herpes Virus Entry Mediator B; Herpesvirus Entry Mediator B; CD112; PVRL2; HVEB; PRR2

    		Human HEK293
    CD112 Protein, Human (HEK293, His) is a recombinant human CD112 expressed in HEK 293 cells with a His tag at the N-terminus. Recombinant Human CD112 can be used as cell surface ligands for the human DNAM-1 (CD226) activating molecule.
  • HY-P78064
    B7-2/CD86 Protein, Human (Biotinylated, HEK293, His-Avi)

    CD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; BU63; FUN-1; LAB72; MGC34413; CD28LG2

    		Human HEK293
  • HY-P78084
    PVR/CD155 Protein, Human (Biotinylated, 323a.a, HEK293, His-Avi)

    CD155; HVED; NECL5; Necl-5; nectin-like 5; PVR; PVS; Tage4; PVSFLJ25946; FLJ25946

    		Human HEK293
Cat. No. Product Name Effect Purity