1. Screening Libraries
  2. Cytoskeleton Compound Library

Cytoskeleton Compound Library

Cat. No.: HY-L060
Library Contents: XLSX PDF SDF

The cytoskeleton is responsible for contraction, cell motility, movement of organelles and vesicles through the cytoplasm, cytokinesis, intracellular signal transduction, and many other functions that are essential for cellular homeostasis and survival. It accomplishes these tasks through three basic structures: F-actin, microtubules, and intermediate filaments (IFs). The cytoskeleton is a dynamic structure where the three major filaments and tubules are under the influence of proteins that regulate their length, state of polymerization, and level of cross-linking. Since cytoskeleton is involved in virtually all cellular processes, cytoskeletal protein aberrations are the underlying reason for many pathological phenotypes, including several cardiovascular disease syndromes, neurodegeneration, cancer, liver cirrhosis, pulmonary fibrosis, and blistering skin diseases.

MCE designs a unique collection of 701 cytoskeleton-related compounds mainly focusing on the key targets in the cytoskeleton signal pathway and can be used in the research of cytoskeleton signal pathway and related diseases.

MCE Cytoskeleton Compound Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 687 compounds supplied in 10 mM solution, 12 compounds supplied in 2 mM solution and 2 compounds supplied in 3 mg/mL solution.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

Get quote In-stock
50 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

Get quote In-stock
100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

Get quote In-stock
2 × 100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

Get quote In-stock

Please contact us at

[email protected]

Top Publications Citing Use of Products
  • Description

  • Product Details

  • Documentation

Description
& Advantages

•   A unique collection of 701 small molecules used for cytoskeleton research.

•   Targets such as Kinesin, Microtubule/Tubulin, Arp2/3 Complex, Bcr-Abl, etc.

•   Bioactivity and safety confirmed by preclinical research and clinical trials, some compounds have been approved by FDA.

•   A useful tool to study cytoskeletal protein aberrations involved diseases such as cardiovascular disease, neurodegeneration, cancer, liver cirrhosis, etc.

•   Structurally diverse, medicinally active, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 701 cytoskeleton compounds supplied as pre-dissolved Solutions or Solid
Solution: 687 compounds supplied in 10 mM solution, 12 compounds supplied in 2 mM solution, 2 compounds supplied in 3 mg/mL solution.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Documentation

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Container *

    Remarks

    Inquiry Online

    Inquiry Information

    Product Name:
    Cytoskeleton Compound Library
    Cat. No.:
    HY-L060
    Quantity:
    MCE Japan Authorized Agent:

    Request SDF File

    Please enter your email address. We will send your requested SDF file to you as soon as possible.

    • 96-well Plate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack