1. Screening Libraries
  2. Toxins for Antibody-Drug Conjugate Research Library

Toxins for Antibody-Drug Conjugate Research Library

Cat. No.: HY-L023
Library Contents: XLSX PDF SDF

Antibody-Drug Conjugates (ADCs), a new class of treatment for cancer, are composed with a monoclonal antibody, a linker and a cytotoxic agent also referred to as a payload. To date, several ADCs have received market approval and more than 60 ADCs are currently in clinical trials. ADCs are one of the fastest growing classes of oncology drugs worldwide.

The payload or cytotoxic agent is the most important unit in the ADC. ADC has the capability to kill cancer cell depending on the potency of the payload. MCE provides 32 highly potent cytotoxins that contain auristatin derivatives, maytansinoids, calicheamicin, duocarmycin, pyrrolobenzodiazepines (PBDs), etc.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Solid) Price Stock
1 mg Get quote In-stock

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Description
& Advantages

•   A unique collection of 32 ADC cytotoxins for targeted therapy research.

•   Used to develop new antibody-drug conjugates targeting cancer.

•   Bioactivity and safety confirmed by preclinical research and clinical trials.

•   Structurally diverse, medicinally active, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 32 ADC cytotoxins supplied as solid powder
Container:
96-well Storage Tubes with Rack
Storage:
-80°C
Shipping:
Blue ice
Documentation

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    Cat. No.:
    HY-L023
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack