CD31/PECAM-1
null CD31, or platelet endothelial cell adhesion molecule-1 (PECAM-1), is a 130 kDa transmembrane glycoprotein of the immunoglobulin superfamily expressed on endothelial cells, platelets, monocytes, neutrophils and subsets of T lymphocytes. Six extracellular Ig-like domains mediate homophilic binding at endothelial junctions, concentrating the molecule at intercellular borders where it governs vascular permeability and the transendothelial migration of leukocytes. CD31 also signals through cytoplasmic immunoreceptor tyrosine-based inhibitory motifs that temper integrin activation and platelet aggregation. Because of its dense expression on vascular endothelium, anti-CD31 staining is the standard method for quantifying microvessel density in tumor angiogenesis studies.
-
CD31/PECAM-1 組換えタンパク質 (5)
- 生物種:
- 由来:
- 生物種:
- 由来:
- 生物種:
- 由来:
- 生物種:
- 由来:
- 生物種:
- 由来:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 分子式: Human
- 分子量: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
