Pattern Recognition Receptors
Pattern Recognition Receptors (PRRs) are a class of receptors capable of recognizing molecules frequently associated with pathogens (Pathogen-Associated Molecular Patterns—PAMPs), or molecules released by damaged cells (the Damage-Associated Molecular Patterns—DAMPs). PRRs bridge nonspecific immunity and specific immunity. PRRs recognize and bind their respective ligands and recruit adaptor molecules through their effector domains, initiating downstream signaling pathways to produce nonspecific anti-infection, antitumor, and other immunoprotective effects. Based on protein domain homology, PRRs can be divided in to five types: Toll-like receptors (TLRs), nucleotide oligomerization domain (NOD)-like receptors (NLRs), retinoic acid-inducible gene-I-like receptors (RLRs), C-type lectin receptors (CLRs), and absent in melanoma-2 (AIM2)-like receptors (ALRs).
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Pattern Recognition Receptors Recombinant Proteins (143)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
