1. Signaling Pathways
  2. PI3K/Akt/mTOR
  3. Akt
  4. Akt1 Inhibitors

Akt1 Inhibitors

Akt

Akt1

Akt2

Akt3

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform Akt1 together.

Please try each isoform separately.

Akt1 Specific Inhibitors
Product Name Akt1 Akt Akt2 Akt3 Akt1 Selectivity Purity
A-674563 hydrochloride
Akt1, Ki: 11 nM
      Selective Inhibitor 99.78%
PF-AKT400
PKBα, IC50: 0.5 nM
      Selective Inhibitor 95.75%
Akt1 and Akt2-IN-1
Akt1, IC50: 3.5 nM
 
Akt2, IC50: 42 nM
  Selective Inhibitor 99.71%
DB07107
Akt1, IC50: 360 nM
      Selective Inhibitor
AKT-IN-2
Akt1, IC50: 5 nM
      Selective Inhibitor
MK-2206 dihydrochloride
Akt1, IC50: 8 nM
 
Akt2, IC50: 12 nM
Akt3, IC50: 65 nM
Pan Inhibitor 99.69%
Capivasertib
Akt1, IC50: 3 nM
 
Akt2, IC50: 7 nM
Akt3, IC50: 7 nM
Pan Inhibitor 99.74%
Ipatasertib
Akt1, IC50: 5 nM
 
Akt2, IC50: 18 nM
Akt3, IC50: 8 nM
Pan Inhibitor 98.42%
M2698
Akt1, IC50: 1 nM
   
Akt3, IC50: 1 nM
Pan Inhibitor >99.0%
AKT inhibitor VIII
Akt1, IC50: 58 nM
 
Akt2, IC50: 210 nM
Akt3, IC50: 2119 nM
Pan Inhibitor 98.93%
GSK-690693
Akt1, IC50: 2 nM
 
Akt2, IC50: 13 nM
Akt3, IC50: 9 nM
Pan Inhibitor 99.22%
Oridonin
Akt1, IC50: 8.4 μM
 
Akt2, IC50: 8.9 μM
  Pan Inhibitor 99.85%
A-443654
Akt1, Ki: 160 pM
 
Akt2, Ki: 160 pM
Akt3, Ki: 160 pM
Pan Inhibitor 99.87%
Uprosertib
Akt1, IC50: 180 nM
 
Akt2, IC50: 328 nM
Akt3, IC50: 38 nM
Pan Inhibitor 98.93%
Afuresertib
Akt1 E17K mutant, IC50: 0.2 nM
 
Akt2, Ki: 2 nM
Akt3, Ki: 2.6 nM
Pan Inhibitor 99.23%
Miransertib
Akt1, IC50: 2.7 nM
 
Akt2, IC50: 14 nM
Akt3, IC50: 8.1 nM
Pan Inhibitor 99.77%
Ipatasertib dihydrochloride
Akt1, IC50: 5 nM
 
Akt2, IC50: 18 nM
Akt3, IC50: 8 nM
Pan Inhibitor 99.59%
AT13148
Akt1, IC50: 38 nM
 
Akt2, IC50: 402 nM
Akt3, IC50: 50 nM
Pan Inhibitor 99.54%
BAY1125976
Akt1, IC50: 5.2 nM (at 10 μM ATP)
 
Akt2, IC50: 18 nM (at 10 μM ATP)
Akt3, IC50: 427 nM (at 10 μM ATP)
Pan Inhibitor 99.86%
Afuresertib hydrochloride
Akt1, Ki: 0.08 nM
Akt1 E17K mutant, IC50: 0.2 nM
 
Akt2, Ki: 2 nM
Akt3, Ki: 2.6 nM
Pan Inhibitor 98.02%
AT7867
Akt1, IC50: 32 nM
 
Akt2, IC50: 17 nM
Akt3, IC50: 47 nM
Pan Inhibitor 98.68%
3CAI
Akt1
 
Akt2
  Pan Inhibitor 99.66%
AT7867 dihydrochloride
Akt1, IC50: 32 nM
 
Akt2, IC50: 17 nM
Akt3, IC50: 47 nM
Pan Inhibitor 99.77%
MK-2206
Akt1, : 8 nM
 
Akt2, : 12 nM
Akt3, : 65 nM
Pan Inhibitor
AKT-IN-3
Akt1, IC50: 1.4 nM
 
Akt2, IC50: 1.2 nM
Akt3, IC50: 1.7 nM
Pan Inhibitor
INY-03-041
Akt1, IC50: 2.0 nM
 
Akt2, IC50: 6.8 nM
Akt3, IC50: 3.5 nM
Pan Inhibitor
Uprosertib hydrochloride
Akt1, IC50: 180 nM
 
Akt2, IC50: 328 nM
Akt3, IC50: 38 nM
Pan Inhibitor