73338-86-0
Chemical Structure
Moracin G
- CAS No.: 73338-86-0
- Formula:C19H16O4
- Molecular Weight:308.33
InChIKey: PRQYZCKJWCQXNM-UHFFFAOYSA-N
SMILES: OC1=CC(O)=CC(C2=CC(C=CC3=C4CC=C(C)CO3)=C4O2)=C1
Biological Activity: Moracin G is a plant-derived kinase modulator and receptor ligand that forms stable bindings with multiple key proteins (AKT1, COX2 and Estrogen receptor 1) and competitively inhibits the activity of specific kinases. By binding to MELK to disrupt cell cycle regulation, Moracin G impairs the survival and proliferation of cancer cells, induces cancer cell apoptosis, and thereby exerts anti-tumor potential. Moracin G can be used in research related to periodontitis and breast cancer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Moracin G | Moracin G is a plant-derived kinase modulator and receptor ligand that forms stable bindings with multiple key proteins (AKT1, COX2 and Estrogen receptor 1) and competitively inhibits the activity of specific kinases. By binding to MELK to disrupt cell cycle regulation, Moracin G impairs the survival and proliferation of cancer cells, induces cancer cell apoptosis, and thereby exerts anti-tumor potential. Moracin G can be used in research related to periodontitis and breast cancer. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Wu Z, et al. Exploring the pharmacological components and effective mechanism of Mori Folium against periodontitis using network pharmacology and molecular docking. Arch Oral Biol. 2022;139:105391. [Content Brief]
- [2]. Prasad P, et al. Computational identification of Moracin G and Isolonchocarpin as potent MELK inhibitors for anticancer drug discovery. Sci Rep. 2025;16(1):397. Published 2025 Dec 6. [Content Brief]
Keywords
