2. ペプチド
  3. Peptide and Derivatives
  4. Hormones and Neuropeptides

Hormones and Neuropeptides

カスタムペプチド

Hormonal peptides are synthesized and secreted by endocrine cells into bloodstream or interstitial fluid. By binding to specific receptors, they regulate a wide range of physiological processes including metabolism, immune function, and reproduction. They are characterized by rapid onset of effect with short sustainability.
Neuropeptides are short-chain peptides produced by neurons and stored in vesicles. Acting as neurotransmitters and neuromodulators, they modulate synaptic transmission and influence functions such as pain perception, emotion, appetite, etc.

Hormones and Neuropeptides (888):

製品番号 製品名 CAS 番号 純度 構造式
  • HY-P0035
    Insulin (human)

    ヒト インスリン

    		11061-68-0 99.92%
    Insulin (human) is a polypeptide hormone that regulates the level of glucose. Insulin (human) can be used for the diabetes mellitus.
    Insulin (human)
  • HY-P1156
    Insulin(cattle)

    Insulin(cattle)

    		11070-73-8
    Insulin cattle is a two-chain polypeptide hormone produced in vivo in the pancreatic β cells. Insulin cattle has often been used as growth supplement in culturing cells.
    Insulin(cattle)
  • HY-P0252
    α-MSH

    α-MSH

    		581-05-5 99.98%
    α-MSH (α-Melanocyte-Stimulating Hormone), an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC).
    α-MSH
  • HY-P0201
    Substance P

    サブスタンスＰ

    		33507-63-0 99.60%
    Substance P (Neurokinin P) is a CNS-penetrant neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R).
    Substance P
  • HY-P0082
    Glucagon (1-29), bovine, human

    グルカゴン

    		16941-32-5 99.91%
    Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis. Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation.
    Glucagon (1-29), bovine, human
  • HY-P11477
    Nesfatin-1 (24-53), human 98.21%
    Nesfatin-1 (24-53), human is a fragment of human Nesfatin-1. Human Nesfatin-1 protein can rapidly inhibit food intake.
    Nesfatin-1 (24-53), human
  • HY-P1389S
    Neuropeptide S (human)-13C2,15N
    Neuropeptide S (human)-13C2,15N is the 13C- and 15N-labeled Neuropeptide S (human) (HY-P1389). Neuropeptide S human, a neuropeptide, is a potent cognate neuropeptide S receptor (NPSR) agonist. Neuropeptide S human can be used for Alzheimer's disease (AD) research.
    Neuropeptide S (human)-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N
  • HY-P11463
    Des-threoninol-octreotide 160841-00-9
    Des-threoninol-octreotide (Compound 13) is a Somatostatin analog. Des-threoninol-octreotide inhibits cloned somatostatin receptors with IC50 values of 13.62 nM, 10.63 nM, 10.95 nM for mSSTR2b, rSSTR5 and hSSTR5, respectively.
    Des-threoninol-octreotide
  • HY-P0035A
    Insulin solution (human) 11061-68-0
    Insulin solution (human) is a polypeptide hormone that regulates the level of glucose. Insulin solution (human) can be used for the diabetes mellitus.
    Insulin solution (human)
  • HY-17571
    Oxytocin 50-56-6 99.87%
    Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma.
    Oxytocin
  • HY-P0059
    Teriparatide

    テリパラチド

    		52232-67-4 99.98%
    Teriparatide (Human parathyroid hormone-(1-34)) is a PTH1 receptor agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research.
    Teriparatide
  • HY-P0276
    GIP, human

    GIP, human

    		100040-31-1 99.94%
    GIP, human, a peptide hormone consisting of 42 amino acids, is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP, human acts as an incretin hormone released from intestinal K cells in response to nutrient ingestion.
    GIP, human
  • HY-P1071
    α-CGRP (human)

    α-CGRP(human)

    		90954-53-3 99.87%
    α-CGRP (human) (Calcitonin gene-related peptide) is a regulatory neuropeptide of 37 amino acids. α-CGRP (human) is widely distributed in the central and peripheral nervous system. α-CGRP (human) is a potent vasodilator and has inotropic and chronotropic effects.
    α-CGRP (human)
  • HY-P0203
    α-CGRP (mouse, rat) 83651-90-5 99.80%
    α-CGRP (mouse, rat), a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP (mouse, rat) can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. α-CGRP (mouse, rat) has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies.
    α-CGRP (mouse, rat)
  • HY-P0090
    Calcitonin (salmon)

    Calcitonin (salmon)

    		47931-85-1 99.96%
    Calcitonin salmon, a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption.
    Calcitonin (salmon)
  • HY-P0206
    Bradykinin

    ブラジキニン

    		58-82-2 99.98%
    Bradykinin is an effective endothelium-dependent vasodilator that can lower blood pressure. Bradykinin can induce contraction of bronchial and intestinal non-vascular smooth muscle, increase vascular permeability, and participate in the mechanism of pain.
    Bradykinin
  • HY-P1464
    Amylin, amide, rat 124447-81-0 99.99%
    Amylin, amide, rat is a potent and high affinity ligand of Amylin receptor AMY1 and AMY3 receptors and variably of AMY2 receptors; binding studies are generally used for the latter receptor.
    Amylin, amide, rat
  • HY-P0055
    GLP-1(7-37) 106612-94-6 99.89%
    GLP-1(7-37) is an intestinal insulinotropic hormone that augments glucose induced insulin secretion.
    GLP-1(7-37)
  • HY-P2273
    Calcitonin (human)

    Calcitonin (human)

    		21215-62-3 99.97%
    Calcitonin (human) is a hypocalcemic hormone. Calcitonin can lower blood calcium levels and inhibit bone resorption. Calcitonin can be used in hypercalcemia or osteoporosis research.
    Calcitonin (human)
  • HY-P0221
    PACAP (1-38), human, ovine, rat

    PACAP 1-38 (human, ovine, rat)

    		137061-48-4 99.99%
    PACAP (1-38), human, ovine, rat is a PAC1 receptor agonist. PACAP (1-38), human, ovine, rat binds to PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2 with IC50s of 4 nM, 2 nM, and 1 nM, respectively. PACAP (1-38), human, ovine, rat increases the α-secretase activity. PACAP (1-38), human, ovine, rat elevates cytosolic Ca2+, increases proliferation and increases phosphorylation of extracellular regulates kinase (ERK) and the epidermal growth factor receptor (EGFR). PACAP (1-38), human, ovine, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP (1-38), human, ovine, rat can be used for neurotrophic and neuroprotective research.
    PACAP (1-38), human, ovine, rat