1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Chemokine & Receptors

Chemokines (or chemotactic cytokines, chemoattractant cytokines) are a large family of small, highly conserved cytokines (8 to 12 kDa) with chemotactic activity. Chemokines mediate the migratory patterns and positioning of all immune cells and are critical for the function of the innate immune system. They are usually categorized into four main subfamilies according to the location of N-terminal cysteine residues: CC, CXC, CX3C and C. Chemokine signals are transduced through binding to G protein-coupled receptor (GPCR) superfamily. Chemokines receptors are divided into four families based on the binding-chemokine type: receptors for CC (CCR), CXC (CXCR), C (XCR1), and for CX3C (CX3CR1). The chemokine signaling network is composed of approximately 50 secreted ligands and 20 GPCRs. Research has shown that this complex system is involved in a variety of physiological processes including mediation of cellular migration during immune responses.

Cat. No. Product Name / Synonyms Species Source
  • HY-P7228
    I-TAC/CXCL11 Protein, Human (HEK293)

    rHuI-TAC/CXCL11; C-X-C motif chemokine 11; Beta-R1; H174; IP-9; SCYB11

    Human HEK293
    I-TAC/CXCL11 Protein, Human (HEK293) is a small cytokine belonging to the CXC chemokine family which can be strongly induced by IFN-gamma, and its receptor CXCR3.
  • HY-P7293
    TARC/CCL17 Protein, Mouse

    rMuTARC/CCL17; C-C motif chemokine 17; SCYA17

    Mouse E. coli
    TARC/CCL17 Protein, Mouse is a novel soluble chemokine mediator of regulatory T-cell migration.
  • HY-P7237
    MCP-1/CCL2 Protein, Human

    rHuMCP-1/CCL2; C-C motif chemokine 2; MCAF; MCP-1; SCYA2

    Human E. coli
    MCP-1/CCL2 Protein, Human is a small cytokine that belongs to the CC chemokine family.
  • HY-P7268
    NAP-2/CXCL7 Protein, Human

    rHuNAP-2/CXCL7; C-X-C motif chemokine 7; Platelet basic protein; MDGF; SCYB7

    Human E. coli
    NAP-2/CXCL7 Protein, Human is one of the CXC chemokine subfamily members, and is well known as a functional activator of neutrophils.
  • HY-P7294
    TECK/CCL25 Protein, Human

    rHuTECK/CCL25; C-C motif chemokine 25; SCYA25

    Human E. coli
    TECK/CCL25 Protein, Human is involved in T cell development and cellular migration to the small intestine.
  • HY-P7227
    IP-10/CXCL10 Protein, Mouse

    rMuIP-10/CXCL10; C-X-C motif chemokine 10; Gamma-IP10; Mob-1

    Mouse E. coli
    IP-10/CXCL10 Protein, Mouse is a member of the CXC chemokine family with pro-inflammatory and anti-angiogenic properties.
  • HY-P7166
    Exodus-2/CCL21 Protein, Human

    rHuExodus-2/CCL21; C-C motif chemokine 21; SLC; SCYA21

    Human E. coli
    Exodus-2/CCL21 Protein, Human is a homeostatic lymphoid chemokine instrumental in the recruitment and organization of T cell and dendritic cells into lymphoid T areas.
  • HY-P7131
    BCA-1/CXCL13 Protein, Human

    rHuBCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13

    Human E. coli
    BCA-1/CXCL13 Protein, Human is identified as an efficacious and selective attractant for B lymphocytes, also acts as a B cell homing chemokine.
  • HY-P7235
    MCP-1/CCL2 Protein, Mouse (HEK293)

    rMuMCP-1/CCL2; C-C motif chemokine 2; MCAF; MCP-1; SCYA2

    Mouse HEK293
    MCP-1/CCL2 Protein, Mouse (HEK293) is a small cytokine that belongs to the CC chemokine family.
  • HY-P7262
    MIP-3 alpha/CCL20 Protein, Human

    rHuMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20

    Human E. coli
    MIP-3 alpha/CCL20 Protein, Human is a C-C motif chemokine ligand, and has CCR6 as its sole receptor.
  • HY-P7282
    RANTES/CCL5 Protein, Human (HEK293)

    rHuRANTES/CCL5; C-C motif chemokine 5; SCYA5

    Human HEK293
    RANTES/CCL5 Protein, Human (HEK293) is a potent CC chemokine, plays an important role in rheumatoid arthritis pathogenesis.
  • HY-P70508
    GRO-alpha/CXCL1 Protein, Human (HEK 293, His)

    Growth-Regulated Alpha Protein; C-X-C Motif Chemokine 1; GRO-Alpha(1-73); Melanoma Growth Stimulatory Activity; MGSA; Neutrophil-Activating Protein 3; NAP-3; CXCL1; GRO; GRO1; GROA; MGSA; SCYB1

    Human HEK293
  • HY-P7284
    SDF-1 alpha/CXCL12 Protein, Human (68a.a)

    rHuSDF-1α/CXCL12; C-X-C motif chemokine 12; PBSF

    Human E. coli
    SDF-1 alpha/CXCL12 Protein, Human (68a.a) is a member of CXC chemokine family, binds to CXCR4 and CXCR7, and is implicated in tumor proliferation, survival, vascularization, metastasis, and immunosuppression.
  • HY-P7379
    IL-8/CXCL8 Protein, Human (CHO)

    rHuIL-8/CXCL8; C-X-C motif chemokine 8; NAP-1; IL8; GCP-1

    Human CHO
    IL-8/CXCL8 Protein, Human (CHO) is a proinflammatory CXC chemokine associated with the promotion of neutrophil chemotaxis and degranulation.
  • HY-P7258
    MIP-2/CXCL2 Protein, Mouse

    rMuMIP-2/CXCL2; C-X-C motif chemokine 2; SCYB2

    Mouse E. coli
    MIP-2/CXCL2 Protein, Mouse is a member of the CXC chemokine family, and can recruit neutrophils to infection sites.
  • HY-P7180
    Fractalkine/CX3CL1 Protein, Human

    rHuFractalkine/CX3CL1; Neurotactin; SCYD1; NTT

    Human E. coli
    Fractalkine/CX3CL1 Protein, Human is found to be associated with inflammatory diseases such as rheumatoid arthritis (RA), rheumatoid vasculitis (RV).
  • HY-P7285
    SDF-1 alpha/CXCL12 Protein, Mouse

    rMuSDF-1α/CXCL12; C-X-C motif chemokine 12; PBSF

    Mouse E. coli
    SDF-1 alpha/CXCL12 Protein, Mouse is a member of CXC chemokine family, binds to CXCR4 and CXCR7, and is implicated in tumor proliferation, survival, vascularization, metastasis, and immunosuppression.
  • HY-P7188
    GRO-alpha/CXCL1 Protein, Mouse

    rMuGRO-α/CXCL1; Growth-regulated alpha protein; C-X-C motif chemokine 1; KC; HSF

    Mouse E. coli
    GRO-alpha/CXCL1 Protein, Mouse could play a major role in inflammation, angiogenesis, tumorigenesis, and wound healing.
  • HY-P70469
    SDF-1 alpha/CXCL12 Protein, Human

    Stromal Cell-Derived Factor 1; SDF-1; hSDF-1; C-X-C Motif Chemokine 12; Intercrine Reduced in Hepatomas; IRH; hIRH; Pre-B Cell Growth-Stimulating Factor; PBSF; CXCL12; SDF1; SDF1A; SDF1B

    Human E. coli
  • HY-P70450
    CCL5 Protein, Human

    C-C Motif Chemokine 5; EoCP; Eosinophil Chemotactic Cytokine; SIS-Delta; Small-Inducible Cytokine A5; T Cell-Specific Protein P228; TCP228; T-Cell-Specific Protein RANTES; CCL5; D17S136E; SCYA5

    Human E. coli
Cat. No. Product Name Effect Purity